Animal wound hemostasis model

Abstract

The invention discloses an animal wound hemostasis model. The animal wound hemostasis model is constructed by using a beagle. The animal wound hemostasis model is constructed by the following steps: S1, weighing and grouping; S2, forming a wound surface; S3, grouping according to a hemostasis mode; and S4, counting the time required for blood flow stopping and the time required for wound recovery,and constructing an animal model. The animal wound hemostasis model has the beneficial effects that the cross wound surface is formed, so that the accuracy of the animal model is reflected; the length, the depth and the width of the wound surface are limited, so that the application range of the model is expanded; through different hemostasis means, the animal wound hemostasis model with different sizes of wound surfaces correspondingly taking different hemostasis measures is constructed; by using an inhibition hemostasis group of an anticoagulant, through cross comparison, the accuracy of constructing the model is reflected, and meanwhile, a delay error is eliminated; and ventilation is carried out in time by using a ventilation pipe, so that dyspnea is avoided, and the consistency of experimental animals is ensured.

Description

technical field [0001] The invention relates to the field of wound hemostasis, in particular to an animal wound hemostasis model. Background technique [0002] With the continuous deepening of global mechanization, safety accidents are prone to occur in urban construction and construction, causing traumatic bleeding. At the same time, heavy machinery oppresses or cuts construction workers, which is very prone to internal or external bleeding; the characteristic of arterial bleeding is fast bleeding. The pressure is high, and it is easy to produce ejection phenomenon when trauma occurs, which affects blood coagulation, and can easily lead to excessive blood loss and shock to death; while venous bleeding is characterized by a slow bleeding speed, and the pressure depends on the specific location of the trauma, but it lasts for a long time, and some parts Air embolism can lead to shock and death; capillary hemorrhage is characterized by osmotic bleeding, less bleeding and short...

AI Technical Summary

Problems solved by technology

[0005] Existing animal trauma models, such as the invention: a method for constructing a miniature pig injury hemostasis animal model and a method for evaluating hemostatic products using the animal model (application number: CN201610900455.8), discloses a method for constructing a miniature pig injury hemostasis animal model And a method for evaluating hemostatic products using the animal model, wherein the method for constructing a miniature pig injury hemostatic animal model includes: fasting the miniature pig without food and water for 24 hours; weighing and anesthetizing the miniature pig; exposing both sides of the groin and The neck and skin preparation were performed; the sensor was inserted into the carotid artery for physiological monitoring; an incision was made at the vertical groin of one femoral artery, and the intermuscular connective tissue was bluntly dissected to expose and separate the femoral artery. Use arterial clips at the heart end to block the blood flow; cut part of the arterial wall between the two arterial clips, release the arterial clip at the distal end first, and then release the arterial clip at the proximal end to obtain a miniature pig injury hemostasis animal model; although using Carotid artery builds a hemostatic model, but for powdered hemostatic products such as hemostatic powder, the arterial clamp is used to apply the drug after clamping, and then the arterial clamp is released, which cannot truly simulate the simulated environment of external trauma. Time-delay error, at the same time, the blood pressure of the carotid artery is too high, and the wound is prone to the risk of large-scale tearing, which is likely to affect the accuracy of the animal model constructed; therefore, there is an urgent need for an animal trauma model with small delay error and accurate simulation.

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