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Oral care composition containing hops extract

A hop extract and oral care technology, applied in the field of oral care, can solve the problems of low bioavailability of active ingredients, and achieve the effects of increasing the residence time and the amount of residence

Active Publication Date: 2020-09-01
HAWLEY & HAZEL BVI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, commonly used oral care products, such as toothpaste, mouthwash, etc., are generally only used for 1-3 minutes. The method affects the residence amount and residence time of the hop extract on the tooth surface, making the bioavailability of the active ingredient extremely low, so how to increase the residence amount of the extract on the tooth surface and prolong the residence time, thereby improving the active ingredient of the extract in the oral cavity Bioavailability in is one of the problems that those skilled in the art need to solve

Method used

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  • Oral care composition containing hops extract
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-4、 comparative example 1-3

[0066] A kind of oral care composition that comprises hops extract, comprises the raw material of following table 1 proportioning, and total amount is prepared into toothpaste by 100 parts; Each gets following each example toothpaste 20g, then gets 40g water, magnetic stirring is evenly obtained 7 A sample of toothpaste slurry, ready to use.

[0067] Table 1:

[0068] .

[0069] After the above 7 corresponding toothpaste pastes were treated with HAp tablets for 2 minutes, the active ingredient residues of the hop extract were detected, and the data are shown in Table 2 below:

[0070] Table 2:

[0071]

[0072] After treating the above 7 corresponding toothpaste pastes with HAp tablets for 5 minutes, the active ingredient residues of the hop extract were detected, and the data are shown in Table 3 below:

[0073] table 3:

[0074]

[0075] The 5 corresponding toothpaste pastes in the above table 3 were treated with the HAp sheet for 10 minutes to detect the residua...

Embodiment 5-8

[0080] A kind of oral care composition that comprises hop extract, comprises the raw material of following table 5 proportioning, and total amount is prepared into toothpaste by 100 parts; Each gets following each example toothpaste 20g, gets 40g water again, magnetic stirring is evenly obtained 4 A sample of toothpaste slurry, ready to use.

[0081] table 5:

[0082]

[0083]

[0084] After the above four toothpaste pastes were treated with HAp tablets for 2 minutes, the active ingredient residues of the hop extract were detected, and the data are shown in Table 6 below:

[0085] Table 6:

[0086]

[0087] After the above four toothpaste pastes were treated with HAp tablets for 5 minutes, the active ingredient residues of the hop extract were detected, and the data are shown in Table 7 below:

[0088] Table 7:

[0089]

[0090] After the above four toothpaste pastes were treated with HAp tablets for 10 minutes, the active ingredient residues of the hop extract ...

Embodiment 9-10

[0095] A kind of oral care composition that comprises hops extract, comprises the raw material of following table 9 proportioning, and total amount is prepared into toothpaste by 100 parts; Each takes 20g of following each example toothpaste, then takes 40g water, magnetically stirs evenly to obtain 2 A sample of toothpaste slurry, ready to use.

[0096] Table 9:

[0097] .

[0098] After the above two toothpaste slurries were treated with HAp tablets for 2 minutes, the residual amount of the active ingredient of the hop extract was detected, and the data are shown in Table 10 below:

[0099] Table 10:

[0100]

[0101] After the above two toothpaste slurries were treated with HAp tablets for 5 minutes, the residual amount of the active ingredient of the hop extract was detected, and the data are shown in Table 11 below:

[0102] Table 11:

[0103]

[0104] After the above two toothpaste slurries were treated with HAp tablets for 10 minutes, the residual amount of ...

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Abstract

The invention discloses an oral care composition containing a hops extract. The oral care composition comprises a hops extract, sodium chloride and an orally acceptable carrier. The oral care composition provided by the invention can significantly improve the retention amount and retention time of the hops extract on the tooth surface.

Description

technical field [0001] The invention relates to the technical field of oral care, in particular to an oral care composition containing hop extract. Background technique [0002] Hops come from the family Cannabaceae, Humulus lupulus Linn., which belongs to the genus Moraceae. It is a perennial winding herb. It has many common names such as hops, hops, yeast flowers, and Hubuzi in China. Hops are mainly distributed in the northern hemisphere, between 30°-60° north latitude, concentrated in Europe, Asia and North America, and only 1 variety is distributed in Morocco in North Africa. Also found in northern and northeastern Asia, and eastern America. China is mainly concentrated in Xinjiang, Gansu and other places. Hops extract means an extract obtained from the extraction of dried flowers, vines, vines or other parts of the plant by any method known in the art, or a synthetic or semi-synthetic equivalent of such an extract or its active components thing. Extracts are commer...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/20A61Q11/00
CPCA61K8/9789A61K8/20A61Q11/00
Inventor 黄美艳岳红雷周康丁学芬
Owner HAWLEY & HAZEL BVI
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