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Medicine for treating kidney deficiency and collateral stasis type diabetic nephropathy in IV stage

A technology for diabetic nephropathy and drugs, applied in drug combination, urinary system diseases, metabolic diseases, etc., can solve the problem that the curative effect needs to be improved.

Active Publication Date: 2020-08-14
上海市嘉定区中医医院
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

A large number of clinical studies have confirmed that traditional Chinese medicine has relatively obvious advantages in reducing the leakage of DN protein and improving renal function, especially according to the etiology and pathogenesis of DN, combined with clinical experience, an empirical prescription for the treatment of diabetic nephropathy (stage IV) with kidney deficiency and collateral stasis has been summarized. Zifen Yishen formula has achieved certain curative effect on improving patients’ symptoms such as backache, edema, dizziness and fatigue, but its curative effect still needs to be improved on improving patients’ renal function and reducing urinary protein

Method used

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  • Medicine for treating kidney deficiency and collateral stasis type diabetic nephropathy in IV stage
  • Medicine for treating kidney deficiency and collateral stasis type diabetic nephropathy in IV stage

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Embodiment Construction

[0010] The present invention is made by removing scrophulariaceae, atractylodes atractylodes, kudzu root, safflower, Alisma, golden cherry, and adding raw oyster, hedyotis, ghost arrow feather, salvia miltiorrhiza, and mulberry octopus on the basis of Ziyue Yishen prescription.

[0011] Zixi Yishen formula uses astragalus to nourish qi and nourish the root, and can also promote water; dogwood and yam strengthen the kidney and nourish the spleen, plus rehmannia glutinosa and crocodile to nourish the kidney and clear away heat, atractylodes invigorates the spleen and dampness, strengthens the root and lowers blood sugar, and kudzu root strengthens the spleen Yang; Gorgon fruit and golden cherry fruit are used together to invigorate the kidney and astringent essence; safflower promotes blood circulation and dredges collaterals; Modern pharmacological studies have shown that Astragalus has the functions of dilating blood vessels, increasing renal blood flow, inhibiting platelet agg...

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Abstract

The invention discloses a medicine for treating kidney-deficiency and collateral stasis-type diabetic nephropathy in IV stage. The medicine is prepared from 25 to 35g of radix astragali seu hedysari,25 to 35g of raw oysters, 25 to 35g of rhizoma smilacis glabrae, 25 to 35g of semen euryales, 13 to 18g of hedyotis diffusa, 8 to 15g of winged euonymus twigs, 8 to 13g of radix salviae miltiorrhizae,8 to 12g of radix rehmanniae, 7 to 12g of Chinese yams, 8 to 12g of cornus officinalis and 5 to 12g of mantis egg-case. The medicine is prepared by removing radix scrophulariae, rhizoma atractylodis,radix puerariae, flos carthami, rhizoma alismatis and fructus rosae laevigatae and adding the raw oysters, the hedyotis diffusa, the winged euonymus twigs, the salviae miltiorrhizae and the mantis egg-case on the basis of a pancreas-nourishing and kidney tonifying formula, so that the effects of promoting blood circulation to remove stasis, removing blood stasis, dredging collaterals and clearingaway heat and toxic materials are enhanced, and the effects of improving kidney function and reducing urine protein are achieved.

Description

technical field [0001] The invention relates to a medicine for treating the fourth stage of diabetic nephropathy of kidney deficiency and collateral stasis type, in particular a medicine prepared by adding and subtracting prescriptions on the basis of empirical prescription Zibi Yishen prescription. Background technique [0002] Diabetic nephropathy (DN) is a common and refractory microvascular complication of diabetes, and it is one of the main causes of death and disability in patients. Early detection of kidney damage, seeking active and effective treatment, and maximizing the control of DN (stage IV) disease are of great significance for delaying the progression of the disease and improving the quality of life of patients. Modern studies have shown that the occurrence and development of DN are closely related to protein non-enzymatic glycosylation, high blood viscosity, and hemodynamic abnormalities caused by high blood sugar. At present, the "Guidelines for the Prevent...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61P3/10A61P13/12A61K35/618A61K35/64
CPCA61K36/481A61K35/618A61K36/90A61K36/896A61K36/62A61K36/748A61K36/80A61K36/28A61K36/11A61K36/19A61K36/34A61K36/37A61K36/537A61K36/804A61K36/8945A61K36/40A61K35/64A61P3/10A61P13/12A61K2300/00
Inventor 胡春平严军蔡以生张艺冯珍凤陈见纺刘曼曼师金娟
Owner 上海市嘉定区中医医院
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