A kind of preparation method of Wushenqi oral solution and application thereof
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A technology of filtrate and temperature control, applied in the field of medicine, can solve the problems of undisclosed effect and research, and achieve the effect of obvious effect and obvious therapeutic effect.
Active Publication Date: 2022-02-08
HUBEI WEISHI BIO PHARMA
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There is no research on the treatment of gastric ulcer with Wushenqi Oral Liquid, and there is no published research on the effect and research on the preparation process of porcine protein-free serum in Wushenqi Oral Liquid on its efficacy in treating gastric ulcer
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preparation example Construction
[0017] 1. Preparation of porcine protein-free serum
[0018] In order to obtain porcine protein-free serum that meets the requirements, it will be prepared through pretreatment, column mixed bed treatment, ultrafiltration treatment and post-treatment.
[0019] A preparation method of pig protein-free serum, comprising the following steps:
[0020] Pretreatment: Take pig blood for anticoagulation treatment, add purified water to adjust the pH value, add adsorbent for adsorption, heat and boil for denaturation treatment, and collect the first filtrate by filtration;
[0021] Column-mixed bed treatment: the first filtrate is concentrated to obtain a first concentrate, and after centrifugation, the supernatant is taken, passed through a column-mixed bed, and the effluent is collected, and the effluent is insulated and filtered to obtain a second filtrate;
[0022] Ultrafiltration treatment: passing the second filtrate through an ultrafiltration column to collect the permeate;
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Embodiment 1
[0034] Example 1: 10 parts of porcine protein-free serum, 20 parts of ginseng, 10 parts of astragalus, 10 parts of codonopsis, 8 parts of crocodile, 4 parts of red ginseng, 5 parts of safflower, 5 parts of Ophiopogon japonicus, 15 parts of Schisandra chinensis in Example 1 , 8 parts of Acanthopanax, 5 parts of Banzhilian, 5 parts of Salvia, 3 parts of Lycium barbarum, 3 parts of Rehmannia glutinosa and 3 parts of honey.
Embodiment 2
[0035] Example 2: 20 parts of pig protein-free serum, 10 parts of ginseng, 8 parts of astragalus, 7 parts of codonopsis, 7 parts of crocodile, 8 parts of red ginseng, 10 parts of safflower, 3 parts of Ophiopogon japonicus, 1 part of Schisandra chinensis in Example 1 , Acanthopanax 5 parts, Scutellaria barbata 3 parts, Salvia miltiorrhiza 1 part, Lycium barbarum 1 part, Rehmannia glutinosa 2 parts and honey 2 parts.
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Abstract
The invention discloses a preparation method and application of Wushenqi oral solution. The preparation method of the pig protein-free serum comprises: taking pig blood for anticoagulant treatment and denaturation treatment, collecting the first filtrate; the first filtrate is concentrated to obtain the first concentrated solution, and after centrifugation, the supernatant is taken to flow through the column mixed bed, and the effluent is collected. Liquid, filtered to obtain the second filtrate; flow the second filtrate through the ultrafiltration column to collect the permeate; concentrate the permeate to obtain the second concentrate, add pharmaceutical grade activated carbon for adsorption treatment, heat up to 80 °C and filter, the filtrate is passed through After preparation, fill it into an oral liquid bottle and seal it, and store it in a cool place after sterilization. The pig protein-free serum obtained by the preparation method of the invention has dry matter content and trace element content as high as 75.1% and 0.092% respectively, and the trace element content is higher than the average level of trace element contained in human serum. The Wushenqi oral solution prepared by the pig protein-free serum provided by the invention has obvious therapeutic effects on gastric and duodenal ulcers.
Description
technical field [0001] The invention relates to the technical field of medicine, in particular to a preparation method and application of Wushenqi oral solution. Background technique [0002] Wushenqi Oral Liquid is formulated with ginseng, Codonopsis radix, Scrophulariaceae, red ginseng and Salvia miltiorrhiza as the five ginseng, supplemented with astragalus and porcine protein-free serum. It is used for shortness of breath, laziness, fatigue, dizziness, soreness of the waist and knees caused by deficiency of qi and blood and deficiency of kidney yang. It can also enhance the body's immunity, nourish the lungs and kidneys, and has obvious effects on lung cancer and liver cancer. inhibition. Clinically, it has curative effects on chronic cough due to lung deficiency, asthma, hemoptysis due to tuberculosis, night sweat, waist and knee pain due to kidney deficiency, impotence and nocturnal emission, neurasthenia, and red blood cell drop after chemotherapy and radiotherapy. ...
Claims
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