A kind of medical n-butyl ester glue with high impact resistance and high hydrophilicity
A high impact resistance, n-butyl ester technology, used in the field of medical adhesives, can solve the problems of poor impact resistance and low hydrophilic properties, and achieve the effects of excellent bonding effect, complete hemostasis, and improved water resistance.
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Embodiment 1
[0032] The medical n-butyl glue with high impact resistance and high hydrophilicity of this embodiment is composed of the following raw materials: flexible copolymer modified α-ethyl cyanoacrylate, hydrophilic modified α- n-octyl cyanoacrylate, n-butyl α-cyanoacrylate and additive package.
[0033] The mass ratio of the flexible copolymer modified ethyl α-cyanoacrylate, hydrophilic modified n-octyl α-cyanoacrylate, n-butyl α-cyanoacrylate and composite additives is 4:6:88:2 .
[0034] The flexible copolymer uses 2-carboxyethyl acrylate and butyl acrylate as monomers, and is synthesized by solution copolymerization. The degree of polymerization of the flexible copolymer is 1200.
[0035] The obtained flexible copolymer is reacted with ethyl α-cyanoacrylate by graft modification to obtain flexible copolymer modified α-ethyl cyanoacrylate, and the graft ratio of the flexible copolymer is 30 %.
[0036] The molar ratio of the 2-carboxyethyl acrylate to butyl acrylate is 2:1. ...
Embodiment 2
[0043] The medical n-butyl glue with high impact resistance and high hydrophilicity of this embodiment is composed of the following raw materials: flexible copolymer modified α-ethyl cyanoacrylate, hydrophilic modified α- n-octyl cyanoacrylate, n-butyl α-cyanoacrylate and additive package.
[0044] The mass ratio of the flexible copolymer modified ethyl α-cyanoacrylate, hydrophilic modified n-octyl α-cyanoacrylate, n-butyl α-cyanoacrylate and composite additives is 3:5:91:1 .
[0045] The flexible copolymer uses 2-carboxyethyl acrylate and butyl acrylate as monomers, and is synthesized by solution copolymerization. The degree of polymerization of the flexible copolymer is 800.
[0046]The obtained flexible copolymer is reacted with ethyl α-cyanoacrylate by graft modification to obtain flexible copolymer modified α-ethyl cyanoacrylate, and the graft ratio of the flexible polymer is 15 %.
[0047] The molar ratio of 2-carboxyethyl acrylate to butyl acrylate is 1:1.
[0048]...
Embodiment 3
[0054] The medical n-butyl glue with high impact resistance and high hydrophilicity of this embodiment is composed of the following raw materials: flexible copolymer modified α-ethyl cyanoacrylate, hydrophilic modified α- n-octyl cyanoacrylate, n-butyl α-cyanoacrylate and additive package.
[0055] The mass ratio of the flexible copolymer modified ethyl α-cyanoacrylate, hydrophilic modified n-octyl α-cyanoacrylate, n-butyl α-cyanoacrylate and composite additives is 8:2:86:4 .
[0056] The flexible copolymer uses 2-carboxyethyl acrylate and butyl acrylate as monomers, and is synthesized by solution copolymerization. The degree of polymerization of the flexible copolymer is 1500.
[0057] The obtained flexible copolymer is reacted with ethyl α-cyanoacrylate by graft modification to obtain flexible copolymer modified α-ethyl cyanoacrylate, and the graft ratio of the flexible polymer is 45 %.
[0058] The molar ratio of the 2-carboxyethyl acrylate to butyl acrylate is 3:1.
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