Mesoporous silica (SiO2) and preparation method thereof

Abstract

The invention provides mesoporous silica (SiO2) and a preparation method and application thereof, and belongs to the field of silicone fillers. The specific surface area of the mesoporous SiO2 is 367-407 m2 / g, and the average pore diameter is 11.26-13.65 nm; and the content of surface hydroxyl is 0.498-0.541 mmol / g. The method for preparing the mesoporous SiO2 comprises the steps: a natural mineral (olivine or serpentine) is adopted as a silicon source, the mesoporous SiO2 is prepared through a one-step method, firstly the natural mineral silicon source is added into an acid, surfactant and porogenic agent mixed solution, the mixture is stirred for a period of time at the specific temperature to sufficiently react, after reacting is completed, centrifugal separation is conducted, a silicon-containing precursor is obtained, the silicon-containing precursor is subjected to still standing, filtered, washed and dried and then calcined at the high temperature, then the mesoporous SiO2 is obtained, and then the obtained mesoporous SiO2 is bonded to C18 and then used for high performance liquid chromatography fillers.

Description

technical field [0001] The invention belongs to the field of silica gel fillers, and in particular relates to a mesoporous silica and a preparation method thereof. Background technique [0002] With the continuous development of science and technology fields such as machinery, optics and electronics, the separation of various substances by chromatography has been rapidly developed and widely used in various industries. In particular, high performance liquid chromatography (HPLC), as an important branch of chromatography, has played a pivotal role in the fields of food, biology, medicine and chemical industry, and has become an indispensable detection method in current research. In this field, the chromatographic column plays a very key role, and the chromatographic column packing, as the key to restricting the separation performance of high performance liquid chromatography, has become the direction of the majority of researchers. [0003] At present, commonly used chromato...

AI Technical Summary

Problems solved by technology

The development of this material mainly stems from the fact that in the 1960s, Stober et al. used alkali-catalyzed hydrolysis of ethyl orthosilicate to prepare SiO2 materials, and SiO2 prepared by the sol-gel method. Not only has high purity, but also has good uniformity. The disadvantage is that the preparation process takes a long time, the cost is high, and the prepared SiO2 has no pores. If it is used as a liquid chromatography packing matrix A series of operations such as hole expansion are also required

However, the preparation process has to go through multiple steps such as crushing, mixing and pulping, magnetic separation, stirring and modified stirring, pickling and pressure filtration, washing and drying, and the preparation process is complicated, which greatly increases the production cost.

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