Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medical copolyester and preparation method thereof

A technology of copolyester and esterification, which is applied in the field of materials, can solve the problems of inability to sterilize with steam or boiling water, low disinfection efficiency of medical utensils, and low disinfection temperature, so as to improve the disinfection effect and disinfection efficiency, and is easy to implement and can be used. well controlled effect

Active Publication Date: 2019-09-24
NINGBO MEDICAL CENT LIHUILI HOSPITACL
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the glass transition temperature (Tg) of PET is about 67°C to 81°C. Therefore, the disinfection temperature of medical utensils such as square plates and trays made of PET is low, generally 50°C to 60°C, and water vapor cannot be sterilized. Or boiling water disinfection, resulting in low disinfection efficiency and poor disinfection effect of medical utensils

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medical copolyester and preparation method thereof
  • Medical copolyester and preparation method thereof
  • Medical copolyester and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0022] The invention provides a medical copolyester and a preparation method thereof, which are mainly used to replace polyethylene terephthalate to prepare medical utensils such as square plates and trays, so that the medical utensils can realize high-temperature rapid disinfection and boiling water disinfection, and improve Disinfection effect and disinfection efficiency.

[0023] The preparation method of medical copolyester provided by the invention mainly comprises the following steps:

[0024] (1) Terephthalic acid or its esterified product, triphenyl ether tetracarboxylic acid diimide-bis N-hydroxyethyl, 1,3-propanediol, 1,4-cyclohexanedimethanol and esterification catalyst Mix, and carry out esterification reaction, obtain the first intermediate product, wherein, the structural formula of described triphenyl ether tetracarboxylic acid diimide-two N-hydroxyethyl is as shown in formula (1):

[0025]

[0026] (2) The first intermediate product is subjected to polycond...

Embodiment 1

[0050] 97.0g of dimethyl terephthalate, 24.4g of triphenylene ether tetracarboxylic acid diimide-bis N-hydroxyethyl, 57.0g of 1,3-propanediol and 21.6g of 1,4-cyclohexanedimethanol It was added to the polymerization reactor, and then 0.15% of anhydrous zinc acetate based on the molar amount of dimethyl terephthalate was added. Under an inert atmosphere, react at 180° C. for 4 hours to obtain the first intermediate product.

[0051] Add 0.2% antimony trioxide, 0.15% triphenyl phosphate and 0.1% antioxidant 1010 based on the molar weight of dimethyl terephthalate to the first intermediate product, and gradually reduce the vacuum to below 100Pa , gradually raised the temperature to 270°C, and reacted for 3.5 hours to obtain medical copolyester.

[0052] After testing, the relative number average molecular mass of the medical copolyester is 28000g / moL, and the relative weight average molecular mass is 51200g / moL. 1 H-NMR determines the mol ratio=10:100 of the structural unit of ...

Embodiment 2

[0054] Dimethyl terephthalate 97.0g, triphenylene ether tetracarboxylic acid diimide-bis N-hydroxyethyl 36.6g, 1,3-propanediol 55.1g and 1,4-cyclohexanedimethanol 21.6g It was added to the polymerization reactor, followed by 0.20% tetrabutyl titanate based on the molar amount of dimethyl terephthalate. Under an inert atmosphere, react at 190° C. for 4 h to obtain the first intermediate product.

[0055] Add 0.20% triphenyl phosphate and 0.1% antioxidant 1010 based on the molar weight of dimethyl terephthalate to the first intermediate product, gradually reduce the vacuum to below 80Pa, gradually raise the temperature to 280°C, and react for 4.0 h to obtain medical copolyester.

[0056] After testing, the relative number-average molecular mass of the medical copolyester is 27000g / moL, and the relative weight-average molecular mass is 49200g / moL. 1H-NMR confirms that triphenylene ether tetracarboxylic acid diimide-bis N-hydroxyethyl The molar ratio of the structural unit to th...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Glass transition temperatureaaaaaaaaaa
Relative number average molecular massaaaaaaaaaa
Glass transition temperatureaaaaaaaaaa
Login to View More

Abstract

The invention relates to a medical copolyester and a preparation method thereof. The preparation method of the medical copolyester comprises the following steps: (1) mixing terephthalic acid or an esterified product of the terephthalic acid, triphenyldiether tetracarboxylic acid diimide-bisN-hydroxyethyl, 1,3-propanediol, 1,4-cyclohexanedimethanol and an esterification catalyst, performing an esterification reaction to obtain a first intermediate product, wherein the triphenyldiether tetracarboxylic acid diimide-bisN-hydroxyethyl has a structural formula represented by a formula (1) shown in the description; and performing a polycondensation reaction on the first intermediate product to obtain the medical copolyester. The medical copolyester provided by the invention not only has excellent mechanical properties such as strength, modulus and toughness, but also excellent high-temperature resistance, so that medical utensils prepared by adopting the medical copolyester can be used for disinfection by water vapor or boiling water, wherein the disinfection temperature can reach 100 DEG C or above, and the disinfection effect and the disinfection efficiency are effectively improved.

Description

technical field [0001] The invention relates to the field of material technology, in particular to a medical copolyester and a preparation method thereof. Background technique [0002] At present, medical utensils such as square plates and trays are mostly made of metal and polymer materials. Among them, the polymer material is mainly polyethylene terephthalate (PET). However, the glass transition temperature (Tg) of PET is about 67°C to 81°C. Therefore, the disinfection temperature of medical utensils such as square plates and trays made of PET is low, generally 50°C to 60°C, and water vapor cannot be sterilized. Or boiling water disinfection, resulting in low disinfection efficiency and poor disinfection effect of medical utensils. Contents of the invention [0003] Based on this, it is necessary to provide a medical copolyester and a preparation method thereof for the above-mentioned problems; -Hydroxyethyl, obtained by melting polycondensation of 1,3-propanediol and...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08G63/685
CPCC08G63/6856
Inventor 沈志森裘世杰吴益栋邓红霞崔翔
Owner NINGBO MEDICAL CENT LIHUILI HOSPITACL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com