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Preparation method of soft capsules for resisting aging and improving sleep

A technology for improving sleep and soft capsules, used in capsule delivery, medical preparations containing active ingredients, antidote, etc. It can solve problems such as thrombophlebitis, easy diarrhea, and gastrointestinal dysfunction, and achieve free cell removal base, improve bioavailability, and promote the effect of effective absorption

Inactive Publication Date: 2019-09-10
YUNNAN LVXIN BIOLOGICAL PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Trace elements are an important part of anti-aging drugs, but taking a large amount of various trace element preparations for a long time may cause asexuality, fatigue, gastrointestinal dysfunction, nervousness, mental depression, etc.; although vitamin E has anti-aging effects , but daily oral administration of more than 100 mg for more than 6 months may cause gastrointestinal dysfunction, angular cheilitis, muscle weakness, cheilitis, and may cause hypoglycemia, thrombophlebitis, blood lipids and cholesterol higher
Diarrhea or precipitation with oxalate in the urethra is the most likely to occur after taking a large amount of vitamin C, but middle-aged and elderly people often do not pay attention to the above symptoms, and it is not uncommon to have difficulty urinating; More than 3 grams of ginseng can cause "ginseng abuse syndrome", mainly manifested as hypertension accompanied by nervousness, restlessness, insomnia, agitation or mental confusion, chest tightness, abdominal distension, etc.; Slight abdominal pain, nausea, and vomiting, individual patients have limb numbness, rash, etc. after taking it

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 1) Preparation of inner material liquid

[0029] Mix and stir 100g of cannabidiol, 100g of astaxanthin, and 200g of hemp oil evenly to obtain the inner material liquid of the soft capsule, which is set aside.

[0030] 2) Preparation of gelatin solution

[0031] Add 450g of gelatin, 425g of purified water, and 150g of glycerin into the flask in sequence, heat to 75°C and keep stirring until completely dissolved to make a gelatin mixture; filter the gelatin mixture with a 100-mesh filter cloth, and filter the filtrate at a vacuum degree of -0.08MPa , at a temperature of 60.0°C, stir until no bubbles are released from the solution; slowly break the vacuum, and filter the resulting gelatin solution through a 100-mesh filter cloth again; keep the filtrate at 60°C for 14 hours, and set aside.

[0032] 3) Pressed pills

[0033] Put the inner material liquid and gelatin liquid prepared in step 1) and step 2) in a soft capsule pill press machine, adjust the discharge speed, co...

Embodiment 2

[0037] 1) Preparation of inner material liquid

[0038] Mix and stir 100g of cannabidiol, 100g of astaxanthin, and 200g of peanut oil evenly to obtain the inner material liquid of the soft capsule, which is set aside.

[0039] 2) Preparation of gelatin solution

[0040]Add 450g of gelatin, 425g of purified water, and 150g of glycerin into the flask in sequence, heat to 75°C and keep stirring until completely dissolved to make a gelatin mixture; filter the gelatin mixture with a 100-mesh filter cloth, and filter the filtrate at a vacuum degree of -0.08MPa , at a temperature of 60.0°C, stir until no bubbles are released from the solution; slowly break the vacuum, and filter the resulting gelatin solution through a 100-mesh filter cloth again; keep the filtrate at 60°C for 14 hours, and set aside.

[0041] 3) Pressed pills

[0042] Put the inner material liquid and gelatin liquid prepared in step 1) and step 2) in a soft capsule pill press machine, adjust the discharge speed, c...

Embodiment 3

[0046] 1) Preparation of inner material liquid

[0047] Mix and stir 100g cannabidiol, 200g astaxanthin, and 300g castor oil evenly to obtain the material liquid in the soft capsule, which is set aside.

[0048] 2) Preparation of gelatin solution

[0049] Add 450g of gelatin, 425g of purified water, and 150g of glycerin into the flask in sequence, heat to 75°C and keep stirring until completely dissolved to make a gelatin mixture; filter the gelatin mixture with a 100-mesh filter cloth, and filter the filtrate at a vacuum degree of -0.08MPa , at a temperature of 60.0°C, stir until no bubbles are released from the solution; slowly break the vacuum, and filter the resulting gelatin solution through a 100-mesh filter cloth again; keep the filtrate at 60°C for 14 hours, and set aside.

[0050] 3) Pressed pills

[0051] Put the inner material liquid and gelatin liquid prepared in step 1) and step 2) in a soft capsule pill press machine, adjust the discharge speed, control the inn...

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PUM

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Abstract

The invention discloses a preparation method of soft capsules for resisting aging and improving sleep. The soft capsules comprise soft capsule shells and inner capsule material liquid. Each part of the inner capsule material liquid is prepared by mixing, by weight, 1 part of cannabidiol, 0.2-5 parts of astaxanthin and 2-5 parts of vegetable oil; each part of the capsule shells is prepared from, byweight, 1 part of gelatin, 0.5-2 parts of purified water and 0.2-1 part of glycerinum; the soft capsules are prepared through dissolution, degasification, pelleting, shape fixation, cleaning and drying. According to the preparation method, the nerve protection and anxiety resistance effects of the cannabidiol and the antioxidation effect of the astaxanthin are combined; through combined use of the cannabidiol and the astaxanthin, a good sleep resistance effect is achieved, free radicals of cells are scavenged, and aging is delayed.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a preparation method of anti-aging and sleep-improving soft capsules. Background technique [0002] With the rapid development of society, people's work pressure and life pressure are increasing, resulting in many people's nervousness, heart palpitations, trance, restless sleep and food. Insomnia and easy aging are common conditions for most people in today's society. According to relevant statistics, about 50% of people around the world suffer from insomnia. Among them, about 20-30% are caused by different sleep disorders, and the proportion in developed countries and cities may be higher. Insomnia can cause fatigue, restlessness, general malaise, listlessness, sluggish response, headache, and inability to concentrate. In severe cases, it can lead to functional diseases such as schizophrenia, depression, anxiety, and autonomic dysfunction. [0003] Although there...

Claims

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Application Information

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IPC IPC(8): A61K31/122A61K9/48A61P39/06A61K31/05
CPCA61K9/4816A61K9/4858A61K31/05A61K31/122A61P39/06A61K2300/00
Inventor 王钲霖刘胜贵李智高付彬彬孔令羽
Owner YUNNAN LVXIN BIOLOGICAL PHARMA CO LTD
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