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Compound probiotics lactobacillus powder for treating irritable bowel syndrome (IBS) and application thereof

A technology of irritable bowel syndrome and compound probiotics, which is applied in the direction of anti-inflammatory agents, powder delivery, drug combination, etc., can solve the problems of different curative effects, different content, hidden safety hazards, etc., achieve broad market prospects and reduce inflammatory reactions , the effect of improving symptoms

Active Publication Date: 2019-08-27
BEIJING SCITOP BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although drug therapy (such as rifaximin, etc.) has a good curative effect, it is difficult to apply it on a large scale because of its high price and side effects
Although the low-fermentable carbohydrate (FOODMAP) diet therapy has been widely praised by the medical community, its curative effect on different individuals is quite different, and it is difficult to implement strict restrictions on dietary ingredients
Although fecal bacteria transplantation has achieved certain results in some patients, it has certain safety hazards
From the perspective of regulating the intestinal flora, the use of probiotics to treat irritable bowel syndrome (IBS) can achieve significant results, but the curative effects vary due to the different strains and contents of probiotics

Method used

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  • Compound probiotics lactobacillus powder for treating irritable bowel syndrome (IBS) and application thereof
  • Compound probiotics lactobacillus powder for treating irritable bowel syndrome (IBS) and application thereof
  • Compound probiotics lactobacillus powder for treating irritable bowel syndrome (IBS) and application thereof

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Effect test

Embodiment 1

[0058] Embodiment 1: The present invention can effectively treat irritable bowel syndrome (IBS), improve symptoms, reduce inflammatory response Response and regulation of the characteristics of intestinal flora .

[0059] 1. Research object

[0060] A total of 76 patients with IBS who met the Rome III diagnostic criteria in the outpatient and inpatient departments of the Department of Gastroenterology of a hospital were selected as the research objects, aged 18-80 years, regardless of gender. All patients have completed blood and urine routine, liver and kidney function, abdominal ultrasound, chest plain film, gastrointestinal endoscopy, and capsule endoscopy, and no obvious organic changes were found. Exclusion criteria: accompanied by other gastrointestinal lesions, heart, liver and kidney insufficiency, malignant tumors, diabetes, patients with a history of abdominal surgery, pregnant or breastfeeding women, taking drugs that affect the observation of this test within 4...

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Abstract

The application provides compound probiotics powder for treating irritable bowel syndrome (IBS). The compound probiotics powder is prepared from lactobacillus casei Zhang, bifidobacterium animalis subsp. lactis V9 and lactobacillus plantarum P-8; the compound probiotics powder is obtained through optimizing, compounding and combining nutrient substances with different properties; the compound probiotics powder can regulate intestinal flora, effectively treats the IBS, can obviously improve symptoms, and reduces inflammatory responses, thereby solving the problems that existing compound probiotics lactobacillus powder is single in flora composition, low in viable count, and poor in probiotics safety, and is lacking in probiotics preparations which effectively treat the IBS; the compound probiotics powder has wide market prospects.

Description

technical field [0001] The application belongs to the field of biological preparations, in particular to a compound probiotic powder for treating irritable bowel syndrome and its application. Background technique [0002] In recent years, with the in-depth research on intestinal flora and the rapid development of high-throughput sequencing technology, "intestinal flora" has appeared more and more frequently in people's sight, and its important role in the host body has continued. It was revealed that it is called "the forgotten organ" and has become an important term related to human health. The intestinal flora not only participates in the formation of body functions such as energy metabolism regulation, heterologous substance metabolism, cell repair and cognitive system in the host, but more importantly, there is a certain interaction between the intestinal flora and the immune system, making the intestinal The microbiota is closely related to the health of the host. The...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K9/19A61P1/00A61P29/00A61K31/7004A61K31/702A61K31/718A61K35/745
CPCA61K9/19A61K31/7004A61K31/702A61K31/718A61K35/745A61K35/747A61P1/00A61P29/00A61K2300/00
Inventor 马杰张凌宇杨慧娟张建军宋继宏
Owner BEIJING SCITOP BIO TECH CO LTD
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