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Bacteriostatic solution and preparation method thereof

A solution and solution mixing technology, applied in the direction of pharmaceutical formulations, antibacterial drugs, antifungal agents, etc., can solve the problems of slow effect, general effect, multiple effects, etc., achieve strong inhibitory effect, good skin itching, skin itching relief and inhibition The effect of bacteria

Inactive Publication Date: 2019-08-16
周林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Application No. 201810759137.3 patent "A fungus spirit antibacterial solution for treating skin inflammation", the antibacterial solution is composed of centipede, scorpion, realgar, light powder, neem bark, camphor, hibiscus bark, rhubarb, nepeta , cicada slough, cnidium, oyster, flavescens, pituitary bark, acetic acid and water. There are many kinds of raw materials, but the effect is average and the effect is slow. How to prepare a raw material with simple composition, quick effect and antibacterial effect A good antibacterial solution has become an urgent problem for people to solve

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  • Bacteriostatic solution and preparation method thereof
  • Bacteriostatic solution and preparation method thereof
  • Bacteriostatic solution and preparation method thereof

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preparation example Construction

[0027] The present invention also provides the preparation method of above-mentioned antibacterial liquid, comprises the steps:

[0028] (1) Grind Sophora flavescens, Cortex Phellodendri, Fructus Cnidii, and aloe vera, then add them to 3000-5000 parts of boiled deionized water, soak and concentrate, filter, take the filtrate, and record it as solution A;

[0029] (2) chlorhexidine acetate is mixed with ethanol solution to obtain B solution;

[0030] (3) Menthol, ethylparaben, solution A and solution B are mixed to obtain a bacteriostatic solution.

[0031] In the present invention, first mix and pulverize Sophora flavescens, Cortex Phellodendri, Fructus Cnidii, and Aloe Vera until the particle size is 500-800 μm, more preferably 500-650 μm; the application has no special requirements for the specific method of pulverization, and conventional The above-mentioned raw materials can be crushed to the specified particle size; after the crushing is completed, it is soaked and conce...

Embodiment 1

[0036] Weigh 12g of Sophora flavescens, 15g of Phellodendron Phellodendri, 6g of Fructus Cnidii, and 5g of Aloe Vera, and grind them in a mortar until the particle diameter of the raw materials reaches 550 μm; Ionized water is always in a boiling state. When the total volume of the mixed solution is 650ml, stop soaking and concentrating, then filter the mixed solution, remove the filter residue by suction filtration, and obtain the filtrate as solution A;

[0037] Weigh 3g of chlorhexidine acetate and 32g of ethanol with a volume fraction of 75%, mix the two, and stir at a speed of 100rpm for 1.5h, so that the two are completely miscible, and obtain B solution;

[0038] Take menthol 2g, ethylparaben 7g, mix the two raw materials with the above-mentioned A solution and B solution, stir at a speed of 60rpm for 0.5h, filter to remove impurities in the mixed solution, and the obtained filtrate is recorded as pH bacteria liquid.

[0039] The bacteriostatic solution prepared above ...

Embodiment 2

[0041] Weigh 18g of Sophora flavescens, 20g of Phellodendron Phellodendri, 10g of Fructus Cnidii, and 8g of aloe, mix them, and grind them in a mortar until the particle diameter of the raw materials reaches 750 μm; Ionized water is always in a boiling state, stop soaking and concentrating when the total volume of the mixed solution is 700ml, then filter the mixed solution, filter with suction to remove the filter residue, and obtain the filtrate as solution A;

[0042] Weigh 5 g of chlorhexidine acetate and 50 g of ethanol with a volume fraction of 70%, mix the two, and stir at a speed of 120 rpm for 2.5 h to make the two completely miscible to obtain solution B;

[0043] Take menthol 6g, ethylparaben 10g, mix the two raw materials with the above-mentioned A solution and B solution, stir at a speed of 70rpm for 1h, filter to remove impurities in the mixed solution, and the obtained filtrate is recorded as antibacterial liquid.

[0044]The bacteriostatic solution prepared abo...

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Abstract

The invention provides a bacteriostatic solution, which is prepared from the following effective components: radix sophorae flavescentis, cortex phellodendri, fructus cnidii, aloe, chlorhexidine acetate, ethanol, menthol, ethylparaben and a right amount of water. The bacteriostatic solution is simple in raw material composition; under the action of a certain amount of the radix sophorae flavescentis, the cortex phellodendri, the chlorhexidine acetate, the ethylparaben, the aloe and the menthol, the bacteriostatic solution has good relief and inhibition effects on skin itching caused by bacterial or fungal infection; a good compatibility between the raw materials is achieved; the results of the embodiments show that after being applied to the diseased part for 4-5 times, the bacteriostaticsolution is proved to have a stronger inhibitory effect on staphylococcus aureus, escherichia coli and candida albicans by means of detection of skin infection, the bacteriostasis rate reaches 100%, and the symptoms of redness, swelling and itching of the skin disappear completely; furthermore, the bacteriostatic solution has the effects of cooling and refreshing as well as cleaning and nursing.

Description

technical field [0001] The invention relates to a bacteriostatic liquid, in particular to a bacteriostatic liquid for skin itching. Background technique [0002] Dermatitis refers to skin inflammation caused by various internal and external infections. Bacterial infection has become an important public health problem. When people's skin is infected with bacteria, local redness, swelling, local itching and other symptoms will appear. The reasons are all skin infections. Therefore, the primary problem in the treatment of skin redness and itching is to inhibit the growth and reproduction of bacteria or fungi. [0003] Application No. 201810759137.3 patent "A fungus spirit antibacterial solution for treating skin inflammation", the antibacterial solution is composed of centipede, scorpion, realgar, light powder, neem bark, camphor, hibiscus bark, rhubarb, nepeta , cicada slough, cnidium, oyster, flavescens, pituitary bark, acetic acid and water. There are many kinds of raw mate...

Claims

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Application Information

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IPC IPC(8): A61K36/886A61K36/896A61K9/08A61K47/10A61P17/04A61P31/02A61P31/04A61P31/10A61K31/045A61K31/155
CPCA61K9/0014A61K9/08A61K31/045A61K31/155A61K36/234A61K36/489A61K36/756A61K36/886A61K36/896A61K47/10A61P17/04A61P31/02A61P31/04A61P31/10A61K2300/00Y02A50/30
Inventor 周林
Owner 周林
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