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Plant extract composition having efficacy of resisting inflammation and relieving itching and preparation method and application of plant extract composition

A technology of plant extracts and compositions, which is applied in the direction of drug combinations, anti-inflammatory agents, skin care preparations, etc., can solve the problems of inconvenience and inflammation, and achieve the effect of simple process, small skin irritation, and reasonable and scientific formula

Active Publication Date: 2019-06-11
上海珈凯生物股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to solve the problems of inflammation caused by scalp irritation and inconvenience to people’s lives, the present invention provides a plant extract composition with anti-inflammatory and antipruritic effects, which is reasonable in compatibility, light in color, light in smell, and has no obvious formula contraindications. The composition is of pure natural plant origin and has high safety. While having anti-inflammatory and anti-itching effects, it also has the functions of protecting the scalp, repairing damage, fundamentally repairing the scalp barrier and maintaining the homeostasis of the scalp

Method used

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  • Plant extract composition having efficacy of resisting inflammation and relieving itching and preparation method and application of plant extract composition
  • Plant extract composition having efficacy of resisting inflammation and relieving itching and preparation method and application of plant extract composition
  • Plant extract composition having efficacy of resisting inflammation and relieving itching and preparation method and application of plant extract composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] (1) take by weighing raw material 100g according to the following mass proportions: Vitex 1g, gentian 1g and Polygonum multiflorum 98g, be 80% ethanol aqueous solution with 500g volume percentage under 80 ℃ of temperature conditions to soak and extract, and the extraction times are 3 times, The time of each soaking and extraction is controlled at 48h, and the ethanol extract is obtained by combining;

[0043] (2) filtering and concentrating the ethanol extract obtained in step (1) to 10 times, using macroporous adsorption resin for purification and elution, and the eluent used in the elution step is an aqueous ethanol solution with a volume percentage of 70% to obtain elution liquid;

[0044] (3) after the eluent is concentrated 45 times, diluted with an equal volume of ethanol;

[0045] (4) 0.5g of tartaric acid was added into 500mL water and stirred to obtain a tartaric acid solution; 0.1% tartaric acid solution was added to the eluent obtained in step (3) under a te...

Embodiment 2

[0050] (1) take by weighing raw material 100g according to the following mass proportions: Vitex 98g, gentian 1g and Polygonum multiflorum 1g, use 2000g volume percent to be 90% ethanol aqueous solution to soak and extract under 30 ℃ of temperature conditions, and the extraction times are 3 times , the time of each soaking and extraction is controlled at 2h, and the ethanol extract is combined;

[0051] (2) filtering and concentrating the ethanol extract obtained in step (1) to 50 times, using polyamide resin for purification and elution, and the eluent used in the elution step is an aqueous ethanol solution with a volume percentage of 95% to obtain an eluent ;

[0052] (3) after the eluent is concentrated 45 times, diluted with an equal volume of ethanol;

[0053] (4) 2.0g tartaric acid was added into 500mL water and stirred to obtain a tartaric acid solution; 0.4% tartaric acid solution was added to the eluent obtained in step (2) under a temperature condition of 70 ° C, an...

Embodiment 3

[0058] (1) take by weighing raw material 100g according to the following mass proportions: Vitex 1g, gentian 98g and Polygonum multiflorum 1g, be 75% ethanol aqueous solution with 1000g volume percentage to soak and extract under 55 ℃ of temperature conditions, and the extraction times are 3 times, The time of each soaking and extraction is controlled at 24h, and the ethanol extract is obtained by combining;

[0059] (2) filtering and concentrating the ethanol extract obtained in step (1) to 30 times, using macroporous adsorption resin to purify and elute, and the eluent used in the elution step is an aqueous ethanol solution with a volume percentage of 85% to obtain elution liquid;

[0060] (3) after the eluent is concentrated 20 times, diluted with 2 times the volume of ethanol;

[0061] (4) 50g tartaric acid was added into 500mL water and stirred to obtain a tartaric acid solution; the eluent obtained in step (2) was added with 10.0% tartaric acid solution under a temperat...

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Abstract

The invention relates to the technical field of cosmetics, in particular to a plant extract composition having efficacy of resisting inflammation and relieving itching and a preparation method and anapplication of the plant extract composition. The plant extract composition having efficacy of resisting inflammation and relieving itching is prepared from the following components in percentage by mass of 1-98% of vitex trifolia fruits, 1-98% of radix gentianae and 1-98% of fleeceflower roots. The invention provides the plant extract composition having the efficacy of resisting inflammation andrelieving itching, which is reasonable in compatibility, light in color, light in smell and free from obvious formula contraindications; the composition is from purely natural plants and high in safety, has the efficacy of resisting inflammation and relieving itching, concurrently has the effects of protecting scalp, repairing damage, fundamentally repairing scalp protective screens and maintaining steady state of the scalp, and really meets requirements of consumers for products capable of resisting inflammation and relieving itching for the scalp.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a plant extract composition with anti-inflammatory and antipruritic effects and a preparation method and application thereof. Background technique [0002] As one of the thinnest parts of human skin, the scalp, coupled with the high-density distribution of skin appendages such as pilosebaceous glands, makes it easy for external stimuli such as ultraviolet (UV) and pollutants (PM2.5) to penetrate into the scalp, causing damage to the scalp structure. Damage, resulting in a weaker barrier function of the scalp than that of the trunk skin. At the same time, the scalp is one of the three major oil-producing areas of the human body. The sebum secreted in large quantities can be utilized by microorganisms such as Malassezia, resulting in a large number of microorganisms; while the peroxides produced by old sebum under the action of UV, such as horny peroxide Squalene, malondialdehyd...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/00A61P17/04A61P29/00
Inventor 谢红王光寅卢伊娜
Owner 上海珈凯生物股份有限公司
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