Preparation method and application of chewable tablet containing fruit-vegetable natural polypeptide composition

A technology of polypeptide composition and chewable tablet, which is applied in the field of fruit and vegetable natural polypeptide composition chewable tablet and its preparation, can solve the problems of loss of polypeptide biological activity and function, reduction of polypeptide biological activity, cumbersome operation steps, etc., and avoid polypeptide activity Damaged, fast-absorbed, good-tasting effects

Inactive Publication Date: 2019-04-26
北京中科卓明生物医学研究所有限公司
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  • Abstract
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AI Technical Summary

Problems solved by technology

Simple acid hydrolysis, alkaline hydrolysis and enzymatic hydrolysis to extract polypeptides, if the selected solution system is too acidic or alkaline, may cause irreversible denaturation or excessive hydrolysis and significant changes in molecular conformation of the extracted, making it gradually lose The biological activity and function of the peptide
Moreover, in order to prevent the enzymatic hydrolysis method from continuing to hydrolyze the protease added after the polypeptide extraction, boiling is usually required to inactivate the enzyme, which may reduce or destroy the biological activity of the polypeptide to a certain extent.
[0004] The important thing is that the above methods are all obtained by decomposing proteins to obtain peptides. Overall, the operation steps are cumbersome, more media are introduced, and there are many problems in the biological activity of the obtained peptides.

Method used

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  • Preparation method and application of chewable tablet containing fruit-vegetable natural polypeptide composition
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  • Preparation method and application of chewable tablet containing fruit-vegetable natural polypeptide composition

Examples

Experimental program
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Effect test

Embodiment 1

[0038] Embodiment 1 A kind of preparation method of sweet potato leaf natural active polypeptide extract, the steps are as follows:

[0039] (1) Take sweet potato leaves, cut into cubes, homogenate in an ice bath at 4°C, then add 0.05mol / L pH7.0 phosphate buffer solution twice the weight of pre-cooled sweet potato leaves to soak, and place in a refrigerator at 4°C for 12 hours Afterwards, refrigerate and centrifuge at 4°C, and the supernatant is the crude extract containing natural polypeptides from sweet potato leaves;

[0040](2) Slowly add the eluent to the crude extract containing the sweet potato leaf polypeptide obtained in step (1) to be diluted to a solution containing 50 mg / mL of the polypeptide, and use Sephadex G-50 column, inner diameter 1cm , the column length is 60cm, the eluent is 0.05mol / L, phosphate buffer solution of pH7.0, containing 0.15mol / L sodium chloride solution, the flow rate is 2mL / min, the injection volume is 1mL, and the detection wavelength is 280...

Embodiment 2

[0042] Example 2 Preparation of Natural Polypeptides from Various Fruits and Vegetables

[0043] According to the operation steps of Example 1, respectively extract wolfberry polypeptide, bitter gourd polypeptide, peony seed polypeptide, loquat fruit polypeptide, yacon fruit polypeptide, oat polypeptide, onion polypeptide, perilla polypeptide, tea seed polypeptide, black bean polypeptide, pumpkin flower polypeptide, walnut polypeptide , black fungus polypeptide, peanut polypeptide, dragon fruit polypeptide, golden pear polypeptide, blueberry polypeptide, spirulina polypeptide, grape skin polypeptide, seabuckthorn polypeptide, yam polypeptide, pine pollen polypeptide, wild kiwifruit polypeptide, taro polypeptide, broccoli polypeptide, for use .

Embodiment 3

[0044] Example 3 A preparation method of a chewable tablet of fruit and vegetable natural polypeptide composition:

[0045] (1) Grind the fruit and vegetable natural peptide powder, red dates, and milk powder through a 60-mesh sieve;

[0046] (2) Sequentially weigh 1.5g of wolfberry polypeptide, 1.5g of sweet potato leaf polypeptide, 2.5g of peony seed polypeptide, 1.4g of yacon fruit polypeptide, 3.8g of oat polypeptide, 1.8g of perilla polypeptide, 67.5g of pure red date powder, 20g of milk powder, well mixed;

[0047] (3) Tablet compression: The uniformly mixed raw materials are directly compressed by a tablet machine to obtain finished round chewable tablets with a diameter of 2.5 cm.

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Abstract

The invention provides a chewable tablet containing a fruit-vegetable natural polypeptide composition, and a preparation method of the chewable tablet, and belongs to the field of functional foods. The chewable tablet contains natural active polypeptide powder of various fruits and vegetables, wherein pure red date powder and milk powder are added into the powder. The preparation method comprisesthe following steps: mixing the natural active polypeptide powder of the various fruits and vegetables, the pure red date powder and the milk powder, which are sieved, according to a certain ratio, uniformly mixing, and directly tabletting the mixture into the chewable tablet containing the fruit-vegetable natural polypeptide composition by a tabletting machine after . The chewable tablet has an integral shape, bright and clean appearance, moderate hardness and a good taste, and is convenient to take; by chewing the tablet, active ingredients of the tablet can be directly dispersed in the oralcavity and the digestive tract, thereby being quickly absorbed. The chewable tablet containing the fruit-vegetable natural polypeptide composition has the advantages that the physiological activity of natural polypeptide of the fruits and vegetables is well maintained, and the chewable tablet can be used for preparing health food and food.

Description

technical field [0001] The invention belongs to the technical field of functional foods, and in particular relates to a chewable tablet of fruit and vegetable natural polypeptide composition and a preparation method thereof. Background technique [0002] Peptides are divided into oligopeptides and polypeptides, which are a type of biologically active substances that are condensed by two or more amino acids and connected by peptide bonds. Peptides are structural and functional fragments that make up proteins. Peptides with a molecular weight of 180-10000 Da are usually called small molecule active peptides. Compared with other substances in organisms, their biggest feature is that they have high biological activity and diversity. In organisms, many biologically active substances mostly exist in the form of molecular structure and natural conformation of polypeptides, and also play an important role in the body in the form of natural biological activity. Peptides play a vital...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C9/18A23C9/152A23C9/156A23J3/14A23J3/16A23J3/20A23J3/32
CPCA23C9/18A23C9/1526A23C9/156A23J3/14A23J3/16A23J3/20A23J3/32
Inventor 菅晓勇
Owner 北京中科卓明生物医学研究所有限公司
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