Polyethyleneimine based chloramines type antibacterial cellulose membrane, preparation method and application

Abstract

The invention discloses a polyethyleneimine based chloramines type antibacterial cellulose membrane, a preparation method and application. The preparation method comprises the following steps: step 1,preparing a cellulose solution with the mass concentration being 5wt percent; step 2, performing casting on a base plate to form a regenerated cellulose membrane after the cellulose solution is defoamed, and washing after solidification, so as to obtain a regenerated cellulose gel membrane; step 3, oxidizing the regenerated cellulose gel membrane through a sodium periodate aqueous solution, so asto obtain dialdehyde cellulose gel membrane with the aldehyde group amount being 1 to 3mmol / g; step 4, dipping the dialdehyde cellulose gel membrane into a polyethyleneimine aqueous solution to perform grafting reaction, so as to obtain a polyethyleneimine grafted cellulose membrane; step 5, chloridizing the polyethyleneimine grafted cellulose membrane, so as to obtain the polyethyleneimine basedchloramines type antibacterial cellulose membrane. The preparation method is performed in an aqueous solution, reaction conditions are mild, the technology is simple to operate, and the preparation processes are environmentally friendly; the formed antibacterial cellulose membrane has good biocompatibility and breathability, and the antibacterial and bactericidal properties are excellent.

Description

technical field [0001] The invention relates to the field of polymer material preparation, in particular to a polyethyleneimine chloramine type antibacterial cellulose film, a preparation method and application. Background technique [0002] In recent years, a variety of bacterial diseases caused by microorganisms have brought great harm and panic to human beings; therefore, antibacterial agents with high efficiency and broad spectrum are urgently needed to be developed and applied; among many antibacterial agents, N-halamine antibacterial agents are new Antibacterial agent has the advantages of high efficiency, long-lasting, broad-spectrum, renewable and non-toxic; N-halamine refers to the compound containing N-X bond (X can be Cl, Br, I), which can be composed of The precursor compound of amide or imide group is obtained by reacting with an oxidizing agent (such as hypochlorite); its antibacterial mechanism is due to the release of strong oxidizing halogen cations by N-hal...

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Problems solved by technology

Patent 201410769240.8 uses a chemical oxidation polymerization method to initiate the polymerization of heterocyclic N-halamine antibacterial agent monomers on the surface of nano-bacterial cellulose, and finally obtains a polymer halide antibacterial agent composite nanocellulose film through a halogenation reaction; but the above-mentioned patent involves The precursor of haloamine is a cyclic compound, and the amine undergoing chlorination reaction is a secondary amine

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