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Raspberry extract and preparation method and application thereof

A raspberry, extract technology, applied in the field of medicine, to achieve good application prospects, reduce MDA content, enhance the effect of SOD activity

Inactive Publication Date: 2018-12-25
国珍健康科技(北京)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Modern studies have confirmed that raspberries have the effects of nourishing the kidney, strengthening yang and impotence, strengthening brain and intelligence, beautifying the skin, and preventing and treating cancer, but there are no reports on the effects of raspberries on anti-oxidation of the liver and protection of liver damage

Method used

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  • Raspberry extract and preparation method and application thereof
  • Raspberry extract and preparation method and application thereof
  • Raspberry extract and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A preparation method of raspberry extract, comprising the following steps:

[0041] S1, take the raspberry medicinal material, remove impurities, wash with water, dry, pulverize and pass through an 800-mesh sieve to obtain raspberry powder;

[0042] S2. Add the raspberry powder into an ethanol aqueous solution with a volume percentage concentration of 70% according to a liquid-to-material ratio of 20mL / g, stir evenly, perform ultrasonic extraction at 25kHz, 450W, and 45°C for 45min, and extract twice;

[0043] S3, filtering the alcohol extraction mixture in step S2 to obtain a raspberry alcohol extract, which is then concentrated to obtain a raspberry concentrate whose volume is 1 / 8-1 / 6 of the volume of the raspberry alcohol extract;

[0044] S4. Freeze-dry the raspberry concentrate at -30--40° C. for 25 minutes, grind it into powder and pass it through a 200-mesh sieve to obtain the raspberry extract.

[0045] After testing, the content of raspberry ketone in the rasp...

Embodiment 2

[0047] A preparation method of raspberry extract, comprising the following steps:

[0048] S1, take the raspberry medicinal material, remove impurities, wash with water, dry, pulverize and pass through an 800-mesh sieve to obtain raspberry powder;

[0049] S2. Add the raspberry powder into an aqueous ethanol solution with a concentration of 70% by volume at a liquid-to-material ratio of 25mL / g, stir evenly, perform ultrasonic extraction at 35kHz, 500W, and 50°C for 30min, and extract twice;

[0050] S3, filtering the alcohol extraction mixture in step S2 to obtain a raspberry alcohol extract, which is then concentrated to obtain a raspberry concentrate whose volume is 1 / 8-1 / 6 of the volume of the raspberry alcohol extract;

[0051] S4. Freeze-dry the raspberry concentrate at -40--50° C. for 35 minutes, grind it into powder and pass it through a 200-mesh sieve to obtain the raspberry extract.

[0052] After testing, the content of raspberry ketone in the raspberry extract prep...

Embodiment 3

[0054] A preparation method of raspberry extract, comprising the following steps:

[0055] S1, take the raspberry medicinal material, remove impurities, wash with water, dry, pulverize and pass through an 800-mesh sieve to obtain raspberry powder;

[0056] S2. Add the raspberry powder into an ethanol aqueous solution with a volume percentage concentration of 70% according to a liquid-to-material ratio of 30mL / g, stir evenly, perform ultrasonic extraction at 25kHz, 550W, and 55°C for 50min, and extract twice;

[0057] S3, filtering the alcohol extraction mixture in step S2 to obtain a raspberry alcohol extract, which is then concentrated to obtain a raspberry concentrate whose volume is 1 / 8-1 / 6 of the volume of the raspberry alcohol extract;

[0058] S4. Freeze-dry the raspberry concentrate at -50~-60° C. for 40 minutes, grind it into powder and pass it through a 200-mesh sieve to obtain the raspberry extract.

[0059] After testing, the content of raspberry ketone in the rasp...

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Abstract

The invention relates to a raspberry extract and a preparation method and application thereof, in particular to a raspberry extract prepared by taking raspberries as raw materials which are sequentially subjected to ultrasonic alcohol extraction, concentration and freeze drying and the application of the raspberry extract in preparing health products or drugs that can resist liver tissue oxidationand protect liver tissue from damage. By the arrangement, the content of GSH (glutathione) of the raspberry extract can be greatly increased, SOD (superoxide dismutase) is enhanced, CAT (catalase) activity is remarkably improved, the content of MDA (methane dicarboxylic aldehyde) is reduced, ALT (alanine transaminase), AST (aspartate aminotransferase) and LDH (lactic dehydrogenase) activity can be remarkably decreased, and the raspberry extract has the potential to be developed into health supplement or drugs that protect against liver oxidation and liver damage.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a raspberry extract and its preparation method and application, in particular to a raspberry extract, its preparation method and its application in resisting liver oxidation and protecting liver damage. Background technique [0002] According to statistics released by the World Health Organization in 2016, about 400,000 people die of hepatitis-related complications in my country every year. According to statistics, as of 2016, there were 90 million chronic hepatitis B patients in China, of which 28 million needed treatment, and 7 million needed emergency treatment due to severe liver disease and cancer risk; at the same time, fatty liver and alcoholic liver have become The second largest liver disease, the total number of patients reached 120 million, of which men accounted for more than 80% of the proportion. Almost 1 out of every 13 Chinese people has liver problems, which are ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P1/16A23L33/105A61K131/00
CPCA23V2002/00A61K36/73A61K2236/333A23L33/105A61P1/16A23V2200/32
Inventor 张丽梅李永强侯思远李颖党艳婷温霖李爱民杨晓珺
Owner 国珍健康科技(北京)有限公司
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