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Medicinal composition for treating alcoholic liver injury

A technology for alcoholic liver injury and composition, which can be used in drug combinations, pharmaceutical formulations, plant raw materials, etc., and can solve unseen problems.

Inactive Publication Date: 2014-04-16
CHINA THREE GORGES UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the protective effect of bamboo ginseng polysaccharides on alcoholic liver injury has not been reported, and there is no technology to optimize the combination of the two effective components of bamboo ginseng total saponins and bamboo ginseng polysaccharides to synergistically treat alcoholic liver disease

Method used

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  • Medicinal composition for treating alcoholic liver injury
  • Medicinal composition for treating alcoholic liver injury
  • Medicinal composition for treating alcoholic liver injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Example 1 : the preparation of granules of the present invention

[0079] This embodiment is carried out according to the following steps:

[0080] Bamboo ginseng pre-treatment: use the far-infrared heater produced by Baoding Sanhuan Power Equipment Co., Ltd. to dry the bamboo ginseng produced in Enshi Autonomous Prefecture, Hubei Province at a temperature of 60°C for 40 minutes, and then use Shandong Qingzhou Yikang Traditional Chinese Medicine Machinery The crushing equipment produced by Manufacturing Co., Ltd. crushed it to 40 mesh.

[0081] Then, the obtained bamboo ginseng powder is soaked in 60% ethanol aqueous solution for 2 hours according to the ratio of ethanol aqueous solution volume milliliters to bamboo ginseng powder weight grams of 10, and then heated and refluxed for 3 times, each refluxed extraction for 3 hours, separated removing the extraction residue to obtain an extract; using a liquid drying device to evaporate and dry the obtained extract to ob...

Embodiment 2

[0084] Example 2 : the preparation of granules of the present invention

[0085] This embodiment is carried out according to the following steps:

[0086] Bamboo Participation Treatment:

[0087] Using the far-infrared heater produced by Baoding Sanhuan Power Equipment Co., Ltd., the bamboo ginseng produced in Enshi Autonomous Prefecture, Hubei Province was dried at a temperature of 75°C for 25 minutes, and then crushed with the ginseng produced by Shandong Qingzhou Yikang Traditional Chinese Medicine Machinery Manufacturing Co., Ltd. The equipment crushes it to 25 mesh;

[0088] Then, the obtained bamboo ginseng powder is soaked in 40% ethanol aqueous solution with a concentration of 40% by weight for 3 hours according to the ratio of ethanol aqueous solution volume milliliters to bamboo ginseng powder weight grams, and then heated and refluxed for 4 times, each time refluxed for 4 hours, separated removing the extraction residue to obtain an extract; using a liquid dryin...

Embodiment 3

[0091] Example 3 : the preparation of granules of the present invention

[0092] This embodiment is carried out according to the following steps:

[0093] Bamboo ginseng pretreatment: use far-infrared heaters produced by Baoding Sanhuan Power Equipment Co., Ltd., and dry bamboo ginseng produced in Enshi Autonomous Prefecture, Hubei Province at a temperature of 68°C for 32 minutes, and then use Yikang traditional Chinese medicine machinery in Qingzhou City, Shandong Province to manufacture The crushing equipment produced by Co., Ltd. crushes it to 32 mesh;

[0094] Then, the obtained bamboo ginseng powder is soaked in 80% ethanol aqueous solution with a concentration of 80% by weight for 2 hours according to the ratio of ethanol aqueous solution volume milliliters to bamboo ginseng powder weight gram ratio of 15, and then heated and refluxed for 3 times, each refluxed extraction for 3 hours, separated removing the extraction residue to obtain an extract; using a liquid dryin...

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Abstract

The invention relates to a medicinal composition for treating alcoholic liver injury. The medicinal composition contains Japanese ginseng total saponins and Japanese ginseng polysaccharides serving as active ingredients and a pharmaceutically acceptable carrier. Due to the adoption of a Japanese ginseng total saponin-polysaccharide composition, certain phenomena can be overcome remarkably, the liver function indexes can be lowered very remarkably, MDA (Methylene Dioxyamphetamine) in liver tissues is reduced, SOD (Superoxide Dismutase) and GSH-Px activity are enhanced, and the inflammatory infiltration and fat vacuoles of liver tissues are reduced.

Description

【Technical field】 [0001] The invention belongs to the technical field of traditional Chinese medicine. More specifically, the present invention relates to a pharmaceutical composition for treating alcoholic liver injury. 【Background technique】 [0002] In my country, with the development of society and economy, the accelerated pace of people's work and life, and the influence of cultural customs, China's alcohol consumption has grown rapidly, and the surge in alcohol intake has become an increasingly serious threat to the health of Chinese residents. As early as 2006, China's alcohol consumption has reached 1.8 million tons, and my country's spirits consumption market has leapt to the top in the world, of which 65% of the drinking population is unhealthy drinking, and their single drinking volume is twice the international safe drinking standard; Moreover, the mortality rate and incidence of various diseases caused by alcohol are higher than that of smoking, and the cost of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/258C08B37/00A61P1/16A61K31/715
Inventor 袁丁张长城王洪武何毓敏贺海波李守超罗春华余枫华代艳文张海滨狄国杰曾晓关乔中
Owner CHINA THREE GORGES UNIV
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