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Preparation method and applications of traditional Chinese medicine oral liquid for preventing and treating chicken colibacillosis

A technology for chicken colibacillosis and traditional Chinese medicine oral liquid, which is applied in the directions of antibacterial drugs, pharmaceutical formulations, and drug delivery to achieve the effects of saving labor costs, low prices, and ensuring food safety.

Inactive Publication Date: 2018-10-09
哈尔滨绿达生动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Dissolving Radix Radix Micropowder in water to prepare oral liquid overcomes the shortcomings of droplets and uneven stirring in Radix Radix Micropowder mixing material, and greatly improves the clinical curative effect of Radix Radix Micropowder

Method used

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Embodiment Construction

[0007] A method for preparing a traditional Chinese medicine oral liquid for preventing and treating chicken colibacillosis and its application embodiments are described in detail.

[0008] A traditional Chinese medicine oral liquid for preventing and treating chicken colibacillosis and its preparation method. The implementation plan is as follows: (1) Weigh a certain amount of Radix Radix Radix decoction pieces and put them into an ultrafine pulverizer for pulverization, with a particle size of more than 300 mesh; (2) Mix the micro-powder of Radix isatidis and warm water (about 50-60 degrees) at a ratio of 1:10, mix well, and let stand for more than 8 hours. (3) Take out the supernatant, concentrate it in a sandwich concentrator, and finally prepare an oral solution with a concentration of 2g / mL, sterilize it, and put it into a 250mL opaque special medicine bottle.

[0009] Toxicity or side effects: Acute toxicity and long-term toxicity tests were carried out on mice, and the...

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Abstract

The invention discloses a preparation method and applications of a traditional Chinese medicine oral liquid for preventing and treating chicken colibacillosis, and belongs to the technology of veterinary traditional Chinese medicine. The preparation method comprises: carrying out ultrafine crushing on Radix Isatidis to achieve a particle size of more than 300 mesh, and extracting at a room temperature to prepare the oral liquid. According to the present invention, the disadvantages of energy consumption, damage on active components by high temperature, and the like of the decoction method forpreparing the oral liquid are overcome; the bioavailability of the active components of Radix Isatidis is improved; with the application of the traditional Chinese medicine oral liquid in the treatment of chicken colibacillosis, the traditional Chinese medicine oral liquid with the content of 2.0 g / mL is added to water, and the obtained mixture is drunk by chicken, wherein each chicken is administered according to a ratio of 6 g oral liquid / 1000 g body weight, the oral liquid added with a small amount of water is drunk at one once in a short time, and the chicken colibacillosis can be cured after the oral liquid is continuously taken for 3-5 days; the oral liquid can be used for preventing chicken colibacillosis when chicken colibacillosis is prevalent, wherein each chicken is administeredaccording to a ratio of 4 g oral liquid / 1000 g body weight, the oral liquid added with a small amount of water is drunk at one once in a short time, and the chicken colibacillosis can be prevented after the oral liquid is continuously taken for 3 days; and the clinical treatment effects show that the effective rate is 100%, the prevention rate is more than 90%, and the cure rate is more than 85%in the application of the oral liquid in the treatment of chicken colibacillosis.

Description

technical field [0001] The invention belongs to veterinary drugs, and mainly relates to a preparation method and application of traditional Chinese medicine oral liquid for preventing and treating chicken colibacillosis. Background technique [0002] Escherichia coli disease is a common infectious disease in chickens, which seriously endangers the production performance of chickens. The use of chemical drugs to treat the disease is the main measure taken at home and abroad. Although the treatment effect is good, but because of its high toxicity and long residence time in animals, it is easy to cause animal-derived food and drug residues, pollute the environment, and endanger human health. The development of safe and efficient natural medicines for the prevention and treatment of chicken colibacillosis is an objective requirement of food safety. This traditional Chinese medicine oral liquid comes from the natural plant Radix Isatidis. Medicinal properties, low price. Conte...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/315A61K9/08A61P31/04
CPCA61K9/0053A61K9/08A61K36/315
Inventor 于文会苏景姜晓文郝敬友刘海瑞马晓野徐馨
Owner 哈尔滨绿达生动物药业有限公司
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