Vaginal gel containing multi-effect factors and preparation method thereof

Abstract

The invention relates to the technical field of preparation of medicines for treating vaginitis, particularly relates to a vaginal gel containing multi-effect factors and a preparation method thereof,and solves the technical problems that the antibacterial, lubricating and moisturizing effects of the existing vaginal gel products are not ideal. The vaginal gel contains a conditioned medium extracting solution of mesenchymal stem cells and traditional Chinese medicine extract, can effectively inhibit the propagation of vaginitis-related bacteria and improve the vaginal moistness, is used for treating vaginal inflammation and relieving vaginal dry symptoms or serves as a human body lubricant, simultaneously has the effect of promoting the repair of the squamous epithelial cell layer of thevaginal mucosa, can enable the vaginal mucosa layer to be thinned and repair small injuries in the vagina, can recover the elasticity of the vaginal mucosa and enable the vaginal mucosa to restore elasticity and softness, and is suitable for people suffering from vaginitis and colpoxerosis.

Description

technical field [0001] The invention relates to the technical field of preparation of vaginitis medicines, in particular to a preparation method of vaginal gel containing compound traditional Chinese medicine extracts and pleiotropic factors of mesenchymal stem cells. Background technique [0002] Vaginitis is a common and frequently-occurring disease in women, including bacterial vaginosis, fungal vaginitis and trichomonas vaginitis. The clinical symptoms of vaginitis are mainly manifested as increased vaginal discharge with peculiar smell, genital itching, and causing cervical and uterine infection and pelvic inflammatory disease. The main population of vaginal dryness or atrophic vaginitis is postmenopausal women. According to survey statistics, about half of postmenopausal women have vaginal dryness. The vaginal mucosa is composed of glycogen-rich nonkeratinized stratified squamous epithelium and a fibrous basement membrane. During the reproductive period, the stratifi...

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Problems solved by technology

[0003] Existing treatment products for vaginitis or vaginal dryness are divided into three categories: 1. Western medicines, such as metronidazole, chlorhexidine, miconazole and ketoconazole, etc., are bactericidal and antibacterial. Western medicines have quick effects but are prone to drug resistance and There are side effects; 2. Traditional Chinese medicines, such as Cnidium Fructus Cnidii, Sophora Sophora, Phellodendron Phellodendron, Alum, Licorice Root, Borneol and Kochia Kochia, etc. have the functions of clearing away heat and detoxification, killing insects and relieving itching, and the simple use of traditional Chinese medicines is slow to take effect and cannot relieve symptoms in time; 3. Devices There are two types, one is treatment with ozone or red light and other physiotherapy equipment, which requires patients to go to the hospital for treatment regularly or purchase treatment equipment by themselves, which is more costly; the other is vaginal antibacterial gel such as chitosan and silver ions, Using biological antibacterial raw materials, instant, convenient, fast and economical treatment of vaginitis, the use and curative effect of the gel have been widely recognized

However, the antibacterial, lubricating and moisturizing effects of current vaginal gel products are not ideal enough

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