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Air flow assisting handheld portable electrostatic spinning device and application thereof

An electrospinning, portable technology, applied in the field of hand-held portable electrospinning equipment, can solve the problems of use and product size and shape restrictions, inaccurate coating, large volume, etc., to avoid environmental problems, high degree of integration, The effect of the small size of the device

Active Publication Date: 2018-08-24
GENERAL HOSPITAL OF PLA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the spinning process of this equipment needs to be carried out in a relatively closed environment, and its use and product size and shape will be limited by the equipment
The Chinese patent "An Electrospinning Device" (CN104695031A) discloses a classic spinning device with a compact structure, a high degree of integration, and an adjustable voltage flow rate. The device consists of a drive unit, a propulsion unit, an electrospinning unit and The heat dissipation unit is composed of a miniaturized adjustable high-voltage electrostatic generator module to replace the traditional high-voltage power supply, and it is modularly integrated with other functional units to design and integrate it; however, the device is also equipped with a heat dissipation module and a control module, which increases the The size and weight of the device are not convenient for handheld use
When electrospinning technology is applied in the medical field, this problem will lead to inaccurate coating and loss of drugs
The Chinese patent "A Airflow-guided Directional In-Situ Thermostatic Electrostatic Spraying Device and Its Application" (CN104225738A) discloses an airflow-guided directional in-situ thermolytic electrostatic spraying device. Liquid and medical biomaterials are directly sprayed at the target point, orientation, and in situ, but the device has a low structural integration and a large volume, which is not conducive to portable use

Method used

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  • Air flow assisting handheld portable electrostatic spinning device and application thereof
  • Air flow assisting handheld portable electrostatic spinning device and application thereof
  • Air flow assisting handheld portable electrostatic spinning device and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Such as figure 1 As shown, an airflow-assisted handheld portable electrospinning device according to the present invention includes an insulating shell 1, a large-capacity secondary battery 2, a charging jack 3, a high-voltage wire 4, a high-voltage static electricity generating unit 5, and a high-voltage static electricity generating switch 6 , airflow conduit connector 7, airflow conduit 8, syringe fixing bracket 9, disposable syringe 10, needle fixing bracket 11, stainless steel needle 12, airflow directional cover 13; the handle part of the insulating shell 1 is provided with a detachable insulating cover The large-capacity secondary battery 2 is connected to the high-voltage static electricity generation unit 5 and the charging jack 3 through the high-voltage wire 4; the high-voltage static electricity generation unit 5 is connected to the high-voltage static electricity generation switch 6 through the high-voltage wire 4; The inner side of the handle; the airflow ...

Embodiment 2

[0025]Weigh 2.0 g of polyethylene glycol and mix it with 8.0 g of deionized water, and stir it magnetically in a water bath at 40° C. for 5 hours to completely dissolve the polyethylene glycol to obtain a uniform and transparent spinning solution. Use a disposable syringe 10 to draw an appropriate amount of spinning solution, install it on the syringe fixing bracket 9, adjust the position of the stainless steel needle 12 so that its top is 5 mm away from the front opening of the airflow directional cover 13; connect the electrospinning equipment through the airflow conduit The device 7 is externally connected to an airflow generator, and the gas flow rate in the airflow conduit is 5 L / min; point the front end of the electrospinning equipment vertically to the collector, and the distance from the collector is 11 cm; press the high-voltage static electricity generation switch 6 with the index finger to make the high-voltage static electricity generation unit 5 The generated high-...

Embodiment 3

[0027] 1.0 g of polyvinylpyrrolidone (PVP) was weighed and mixed with 9.0 g of absolute ethanol, and magnetically stirred for 3 hours at room temperature to completely dissolve the PVP to obtain a uniform and transparent spinning solution. Use a disposable syringe 10 to draw an appropriate amount of spinning solution, install it on the syringe fixing bracket 9, adjust the position of the stainless steel needle 12 so that the top is 4 mm away from the front opening of the airflow directional cover 13; connect the electrospinning equipment through the airflow conduit The device 7 is externally connected to an airflow generator, and the gas flow rate in the airflow conduit is 6L / min; point the front end of the electrospinning equipment vertically to the collecting pole, and the distance from the collecting pole is 8 cm; press the high-voltage static electricity generating switch 6 with the index finger to make the high-voltage static electricity generating unit 5 The generated hig...

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PUM

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Abstract

The invention relates to the technical field of electrostatic spinning, in particular to an air flow assisting handheld portable electrostatic spinning device and application thereof. The electrostatic spinning device comprises an insulating shell, a large-capacity secondary battery, a charging slot, a high-voltage wire, a high-voltage static electricity generating unit, a high-voltage static electricity generating switch, an air flow guide pipe connector, an air flow guide pipe, an injector fixing support, a disposable injector, a needle fixing support, a stainless steel needle and an air flow oriented cover. The large-capacity secondary battery is adopted as the power supply, and high-voltage static electricity is generated through the high-voltage static electricity generating unit; theelectrostatic spinning device is externally connected with an air flow generator through the air flow guide pipe connector, the stainless steel needle and the air flow guide pipe are fixedly locatedon the same axis, and electrostatic spinning is conducted with the aid of air flow. The electrostatic spinning device is high in integration degree, convenient to carry and capable of being held by one hand, and the orientation, uniformity and high-efficiency deposition of electrostatic spinning fibers are realized with the aid of air flow.

Description

technical field [0001] The invention relates to an electrostatic spinning device and its application, in particular to a hand-held and portable electrostatic spinning device assisted by an air flow. Background technique [0002] Electrospinning technology is one of the methods for preparing micro-nano fibers and fiber membranes. Its principle is to use a high-voltage electric field to make the polymer solution form a charged jet and eject it from the nozzle. The jet will split and stretch when it flies to the substrate. At the same time, the solvent evaporates, dries, and solidifies, and finally falls to the substrate to form micro-nano fibers. Electrospinning technology has simple process, low cost and high efficiency. Micro-nano fibers and fiber membranes prepared by this technology have the characteristics of high specific surface area, large length / diameter ratio, and high porosity. Therefore, electrospinning technology has shown great application potential in the field...

Claims

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Application Information

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IPC IPC(8): D01D5/00A61M11/02A61M35/00
CPCA61M11/02A61M35/003D01D5/0069D01D5/0092
Inventor 姜凯陈照军沈国震姜源杜辉曹玉杰鲁鸽
Owner GENERAL HOSPITAL OF PLA
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