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Composition with blood lipid lowering effect and preparation method of composition

A composition and blood lipid-lowering technology, which are applied in the direction of medical preparations containing active ingredients, drug combinations, applications, etc., can solve problems such as blood pressure rebound and elevated blood pressure, and achieve increased intestinal peristalsis, lower blood lipids, and inhibit blood pressure. Effects of endogenous lipid synthesis

Active Publication Date: 2018-08-21
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine does not solve the pathological factors that cause blood pressure to rise. Once the drug is stopped, the blood pressure will rebound quickly and the patient must take the drug for life

Method used

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  • Composition with blood lipid lowering effect and preparation method of composition
  • Composition with blood lipid lowering effect and preparation method of composition
  • Composition with blood lipid lowering effect and preparation method of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Weigh the following raw materials in parts by weight: 10 parts of cistanche, 5 parts of tartary buckwheat, 2 parts of green tea, 1 part of lotus leaf, and 2 parts of ebony plum; the above raw materials are mixed, and water of 12 times the total weight of raw materials is added as an extraction solvent. Extract twice at 95°C, each time for 1.5h, filter, and combine the filtrate; the filtrate is concentrated under reduced pressure at 70°C and a relative vacuum of -0.07MPa to obtain a concentrated solution with a density of 1.1g / mL, which is spray-dried and controlled The hot air inlet temperature during spray drying is 180° C. to obtain the material; the material is crushed and passed through an 80-mesh sieve to obtain the traditional Chinese medicine composition.

Embodiment 2

[0029] Weigh the following raw materials in parts by weight: 20 parts of cistanche, 5 parts of tartary buckwheat, 3 parts of green tea, 1 part of lotus leaf, and 2 parts of ebony plum; the above raw materials are mixed, and water of 14 times the total weight of raw materials is added as an extraction solvent. Extract at 100°C for 3 hours, and obtain the filtrate after filtration; the filtrate is concentrated under reduced pressure at 60°C and a relative vacuum of -0.09MPa to obtain a concentrated solution with a density of 1.2g / mL, and the concentrated solution is stored at 80°C and a relative vacuum of -0.07MPa Vacuum drying, crushing through an 80-mesh sieve to obtain a traditional Chinese medicine composition.

Embodiment 3

[0031] Weigh the following raw materials in parts by weight: 12 parts of cistanche, 6 parts of tartary buckwheat, 2 parts of green tea, 2 parts of lotus leaf, and 4 parts of ebony plum; the above raw materials are mixed, and water of 16 times the total weight of raw materials is added as an extraction solvent. Extract at 95°C for 3 times, each time for 1h, filter, and combine the filtrate; the filtrate is concentrated under reduced pressure at 70°C and a relative vacuum of -0.08MPa to obtain a concentrated solution with a density of 1.08g / mL. The concentrated solution is spray-dried and sprayed under control. The hot air inlet temperature during drying is 200° C. to obtain the material; the material is crushed and passed through an 80-mesh sieve to obtain a traditional Chinese medicine composition.

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Abstract

The invention discloses composition with a blood lipid lowering effect. The composition is prepared from the following raw materials in parts by weight: 5-30 parts of herba cistanche, 1-20 parts of tartary buckwheat, 1-20 parts of green tea, 1-20 parts of lotus leaves and 0.2-15 parts of dark plum. The invention further discloses an application of the composition in preparation of medicines or health food with the blood lipid lowering effect. The composition is prepared from the herba cistanche, the tartary buckwheat, the green tea, the lotus leaves and the dark plum, all the five raw materials belong to traditional medicinal and edible materials, and are safe and secure to eat; the herba cistanche as the monarch drug, the tartary buckwheat, the green tea and the lotus leaves as the minister drugs and the dark plum as the adjuvant drug are complementary to one another, and accordingly, scientific compatibility of the monarch, the minister and the adjuvant is realized, effective components with the blood lipid lowering effect such as flavone, polyphenol, active polysaccharide, alkaloid and the like in the five raw materials are effectively enriched, and the synergistic blood lipid lowering effect is achieved by inhibiting exogenous lipid absorption, inhibiting endogenous lipid synthesis, promoting lipid transport and excretion and regulating lipid metabolism.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine health care products, in particular to a composition with hypolipidemic effect and a preparation method thereof. Background technique [0002] Hyperlipidemia is a common and frequently occurring metabolic disease, which refers to excessive blood lipid levels, which can directly cause some diseases that seriously endanger human health, such as atherosclerosis, coronary heart disease, pancreatitis, etc. Hyperlipidemia is common in middle-aged and elderly people, but with changes in diet structure and increased alcohol consumption, the prevalence rate among young people is also increasing year by year. Therefore, people pay more and more attention to the prevention and treatment of hyperlipidemia. [0003] There is no disease name for hyperlipidemia in traditional Chinese medicine. Hyperlipidemia is believed to be caused by deficiency in origin and excess in superficiality, and b...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61P3/06A23L33/105
CPCA23V2002/00A61K36/62A61K36/64A61K36/70A61K36/736A61K36/82A61K2236/331A61K2236/39A61K2236/51A23L33/105A61P3/06A61K2300/00A23V2200/30A23V2250/21
Inventor 萧伟邓辰辰王婧刘世娟许明君高如意柏伟荣
Owner JIANGSU KANION PHARMA CO LTD
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