Solid dispersion containing fermented cordyceps sinensis fungus powder (Cs-4) and preparation method of tablets of solid dispersion

Abstract

The invention relates to a solid dispersion of fermented cordyceps sinensis fungus powder (Cs-4) and preparation of the solid dispersion. The solid dispersion has a formula comprising the following raw materials in parts by weight: 3-12 parts of fermented cordyceps sinensis fungus powder (Cs-4), 3-60 parts of a water-soluble matrix and 0-3 parts of an antioxidant, wherein the water-soluble matrixis selected from polyethylene glycol, polyvinylpyrrolidone, urea, alcohol, hydrolyzed gelatin, sugar, organic acid and a surfactant; the antioxidant is selected from sulfite, vitamins and amino acids;and a preparation method of the solid dispersion comprises the following steps: mixing the water-soluble matrix with the fermented cordyceps sinensis fungus powder (Cs-4), heating and melting, placing into an ice bath for cooling rapidly, solidifying and drying, and grinding to obtain fine powder that is the solid dispersion of the invention. The invention further provides a preparation of the solid dispersion containing the fermented cordyceps sinensis fungus powder (Cs-4).

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a solid dispersion containing fermented Cordyceps powder (Cs-4), and simultaneously the invention also relates to the solid dispersion containing fermented Cordyceps powder (Cs-4) Method for the preparation of tablets. technical background [0002] Cordyceps sinensis (Latin scientific name: cordyceps sinensis) is a rare Chinese medicinal material unique to my country. In fact, it is neither a bug nor a grass, but some special fungi (Cordyceps fungus) invade the larvae of the genus Hepialus living in the soil of the alpine meadow on the Qinghai-Tibet Plateau, and after a winter of growth, it becomes rich in hyphae. The medicinal material of the microbial ascus of the body (it becomes the Chinese medicinal material "Cordyceps sinensis" when the ascus grows from May to July every year). Because the insects of the genus Hepialus are the main hosts of Cordyceps sinensis, they have ...

AI Technical Summary

Problems solved by technology

[0005] Fermented Cordyceps powder (Cs-4), as a drug with Chinese characteristics, represents the new achievements of drug research and application in my country, but with the rapid development of science and technology and the continuous improvement of people's material and cultural needs, hard capsules of traditional technology And tablets seem to be a fly in the ointment, slow onset, and slight adverse effects

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