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Preparation method of total-effect easy-to-absorb nanometer pelelith powder calcium tablet

A technology of powdered calcium tablets and volcanic stones, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, active ingredients of phosphorus compounds, etc., can solve the problems of high phosphorus content in calcium phosphate, difficult to dissolve, and not active calcium, etc., to achieve promotion Lipid metabolism, good absorption effect, no toxic side effects

Inactive Publication Date: 2018-06-08
ZHONG HONG NANO FIBER TECH DANYANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, the vast majority of natural calcium and synthetic calcium preparations are not easily soluble in water, so they are not active calcium. They must be converted into active calcium (ionized calcium) by gastric acid before they can be absorbed and then exerted. Physiological function, not suitable for those with achlorhydria
Among them, the most commonly used calcium gluconate has a large water solubility, so it contains more active calcium, but unfortunately its calcium content is only 10%; calcium carbonate is synthetic calcium, which is the natural calcium contained in oyster shells, and its calcium content reaches 40%. It is the highest among all calcium preparations, and because of the abundant raw materials, the price is cheap, and the market is the largest, but it is difficult to dissolve in water, not active calcium, it must be taken orally after meals and converted into active calcium by gastric acid to be effective; phosphoric acid High in calcium and phosphorus, but not suitable for chronic renal insufficiency

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A preparation method of full-effect and easily absorbable nano volcanic stone powder calcium tablet, the steps are as follows:

[0031] (1) Calculated by weight percentage: volcanic rock powder 22%, bamboo leaf extract 10%, lecithin 1.5%, magnesium stearate 0.2%, tricalcium phosphate 2%, choline 4%, gelatin 5% and the rest Amount of water as raw material;

[0032] (2) Mix grape seed powder, lecithin, magnesium stearate, tricalcium phosphate, choline and water at 40°C for 15 minutes to obtain a mixture A;

[0033] (3) Add edible calcium carbonate powder to mixed solution A, and continue to stir for 40 minutes to obtain mixed solution B;

[0034] (4) After lowering the temperature to 25°C, add gelatin to the mixture B and stir for 10 minutes to obtain the mixture C;

[0035] (5) Filtering the mixture C, removing the filter residue, and freeze-drying to obtain freeze-dried particles;

[0036] (6) Grinding the freeze-dried particles into particles with a particle size of...

Embodiment 2

[0048] A preparation method of full-effect and easily absorbable nano volcanic stone powder calcium tablet, the steps are as follows:

[0049] (1) Calculated by weight percentage: volcanic rock powder 32%, bamboo leaf extract 12%, lecithin 2.6%, magnesium stearate 0.1%, tricalcium phosphate 1.3%, choline 3%, gelatin 3% and the rest Amount of water as raw material;

[0050] (2) Mix grape seed powder, lecithin, magnesium stearate, tricalcium phosphate, choline and water at 35°C for 20 minutes to obtain a mixture A;

[0051] (3) Add edible calcium carbonate powder to mixed solution A, and continue to stir for 30 minutes to obtain mixed solution B;

[0052] (4) After lowering the temperature to 30°C, add gelatin to the mixture B and stir for 20 minutes to obtain the mixture C;

[0053] (5) Filtering the mixture C, removing the filter residue, and freeze-drying to obtain freeze-dried particles;

[0054] (6) Grinding the freeze-dried particles into particles with a particle size ...

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Abstract

The invention provides a preparation method of a total-effect easy-to-absorb nanometer pelelith powder calcium tablet. The method comprises the following steps of mixing grape seed powder, lecithin, magnesium stearate, tricalcium phosphate, choline and water for 10 to 20min at 35 to 48 DEG C to obtain a mixed liquor A; adding edible calcium carbonate powder into the mixed liquor A, and continuously stirring for 30 to 50min to obtain a mixed liquor B; after reducing the temperature to be 25 to 30 DEG C, adding gelatin into the mixed liquor B, and stirring for 10 to 20min to obtain a mixed liquor C; filtering the mixed liquor C, removing a filter residue, and freeze-drying to obtain a freeze-dried particle; grinding the freeze-dried particle to obtain particles with the particle size being 100 to 200 nanometer, adding vitamin D powder, mixing uniformly, and tabletting forming through a tablet machine. The total-effect easy-to-absorb nanometer pelelith powder calcium tablet provided by the invention is good in absorption effect, has an oxidation resisting effect, and can be used for preventing multiple diseases.

Description

technical field [0001] The invention relates to a preparation method of calcium tablets, in particular to a preparation method of full-effect and easily absorbed nano-volcanic stone powder calcium tablets. Background technique [0002] Calcium is originally present in the 60 trillion cells of the human body and is an important nutrient for all functions of the body. In other words, once the calcium is insufficient, the body cannot function normally, which in turn causes various problems. Since calcium is an important nutrient that is life-threatening even if there is a deficiency, once calcium is deficient, it will be absorbed from the bones. The human body excretes calcium from sweat and urine every day. The consumed calcium must also be supplemented from the daily intake of nutrients to achieve the balance of calcium in the body. [0003] At present, there are many calcium supplement products on the market, which can be divided into synthetic calcium and natural calcium:...

Claims

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Application Information

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IPC IPC(8): A61K33/10A61K36/899A61K9/20A61P39/06A61P3/02A61P3/12A61P3/14A61K31/59A61K33/42
CPCA61K33/10A61K9/2063A61K31/59A61K33/42A61K36/899A61K2300/00
Inventor 崔建中
Owner ZHONG HONG NANO FIBER TECH DANYANG
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