A kind of preservation fixative solution for pathological tissue

Abstract

The invention belongs to the technical field of specimen processing, and in particular relates to a preservation fixative for pathological tissue. The preservation fixative for pathological tissue according to the present invention (expressed in parts by mass) is composed of the following components: 10-15 parts of furfural, 8-12 parts of hydroxyl compounds, 4-6 parts of mannitol extract, 6- parts of alliin 10 parts, 6-8 parts of trimethylglycine, 1-3 parts of carbonyl-4, 4-diisoidene-fatty alcohol-phosphate chelate polymer, and 50-60 parts of water. The preservation fixative does not contain formaldehyde and ethanol, does not need to be replaced, is non-toxic, and has no impact on the working environment; the preservation effect of the specimen is good, the bacteriostatic effect is remarkable, it is not mildewed, does not shrink, the color is natural, the tissue is flexible and moist; at the same time, The properties are stable, and the specimens are stored for 6 months at 40℃. The specimens are free of mold spots and rancidity. The preservation solution is clear.

Description

technical field [0001] The invention belongs to the technical field of specimen processing, and in particular relates to a pathological tissue preservation fixative. Background technique [0002] Biopsy pathological diagnosis is the first diagnosis in surgery and is the gold standard. Doctors can make a correct diagnosis based on the test results of the specimens and formulate the next treatment plan for the disease. The accuracy of pathology reports plays a decisive role in the diagnosis and treatment of diseases to a considerable extent. Correct handling of pathological specimens can not only provide an effective guarantee for pathological diagnosis and clinical diagnosis, but also maintain the patient's body and mind, and prevent disputes caused by improper specimen handling. Existing surveys have shown that the current specimen handling methods in the operating room cannot effectively prevent nursing errors. [0003] The most critical steps in the processing of pathol...

AI Technical Summary

Problems solved by technology

However, the long-term use of ethanol-containing preservation solution will easily cause the specimen to lose water, condense and deform. This may be due to the small molecular weight of ethanol, which will penetrate into the interior of the specimen after long-term use.

At the same time, due to the volatility of ethanol, the preservation solution will gradually become invalid, especially in hot areas, the preservation solution is difficult to promote

[0006] Chinese patent CN1047061C discloses an antiseptic preservation solution for corpse specimens. The components of the preservation solution are formulated from benzoate, ethanol, potassium nitrate and glycerol. Although the preservation solution has reliable antiseptic properties, it is safe and non-toxic , the advantage of no bad irritating smell, but the preservation solution has no fixation effect on the tissues of human specimens, and it is easy to cause deformation of the tissue shape, which does not serve the purpose of preserving the original shape of the specimens, which is not conducive to the development of research

However, after 6 months of simulated accelerated storage at 40°C, the specimens appear cloudy and begin to deform. It is not suitable for high temperature and long-term storage.

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