Collagen material for promoting survival of skin with degloving injuries and avulsion injuries

Abstract

Disclosed is a collagen material for promoting the survival of the skin with degloving injuries and avulsion injuries. The collagen material is composed of a collagen sponge and a nutrient solution. Specifically, bovine achilles tendons and pig achilles tendons which serve as raw materials are subjected to enzymatic hydrolysis and purification, collagen is prepared through fine extraction, the collagen sponge is obtained after crosslinking and freeze-drying treatment, and the nutrient solution is obtained. The nutrient solution is added while the collagen sponge is implanted in a wound. The collagen material has the advantages that the collagen material is implanted conveniently and easily applied to the surgical operation, the survival of the skin with the degloving injuries and the avulsion injuries is effectively promoted, the early recovery of the functions of the affected limbs is promoted, the necrosis rate of the skin with the degloving injuries or the avulsion injuries is reduced, the situation that multiple operations are caused by the occurrence of skin necrosis and complications of bone-tendon exposure is avoided, and the surgical complications caused by replantation surgery or flap surgery and the like are reduced to the greatest degree; the collagen material is suitable for hand and foot surgery and treatment of degloving injuries and avulsion injuries of the fourlimbs, and applicable to popularization and application.

Description

technical field [0001] The invention relates to the field of medical materials, and more specifically relates to a collagen material that promotes skin survival in degloving wounds and avulsed wounds. Background technique [0002] Severe skin degloving or avulsion injuries of hands, feet and limbs, especially the treatment of retrograde avulsion or avulsion injuries is a difficult problem in orthopedic treatment. In the past, skin replantation or multiple flap repairs were often used. Skin replantation often results in necrosis or partial necrosis of the skin and exposure of the tendons, which requires another or multiple operations; flap repair surgery is difficult, especially for free flaps, and it is traumatic and risky, so it is only suitable for microsurgery Hospitals with strong technical force carry out the treatment. Patients often have long hospital stays, many surgeries, necrosis or bloated skin flaps, and complications such as skin donor site damage, resulting in...

AI Technical Summary

Problems solved by technology

[0004] Therefore, how to solve the problem of degloving wound and avulsion wound skin survival has become a problem to be solved urgently by those skilled in the art