Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of traditional Chinese medicine composition in Japanese encephalitis

A kind of Japanese encephalitis, composition technology, applied in the application field of ginkgolide composition in the prevention/treatment of Japanese encephalitis

Active Publication Date: 2018-05-04
JIANGSU KANION PHARMA CO LTD
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are no related reports that Ginkgo biloba extract can treat or prevent Japanese encephalitis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of traditional Chinese medicine composition in Japanese encephalitis
  • Application of traditional Chinese medicine composition in Japanese encephalitis
  • Application of traditional Chinese medicine composition in Japanese encephalitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0015] Hereinafter, the present invention will be described in more detail through specific embodiments, so as to better understand the solutions of the present invention and the advantages of various aspects thereof. However, the content of the specific embodiments described below is only for the purpose of illustration, rather than limiting the present invention.

[0016] It should be noted that if the specific conditions are not specified, they are carried out according to the conventional conditions or the conditions suggested by the manufacturer. The raw materials or excipients used, as well as the reagents or instruments used without indicating the manufacturer, can be obtained from the market. conventional products. All percentages, ratios, proportions or parts are by weight unless otherwise indicated.

[0017] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as commonly understood by those skilled in the art. In addit...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of a bilobalide composition in the preparation of a drug for treating Japanese encephalitis. An in-vitro experiment shows that the bilobalide composition is capable of inhibiting the pathological change of a cell BHK-21 infected by JEV. Furthermore, by applying the composition, neurobehavioral symptoms of a suckling mouse can be obviously improved, and the volume and water content of an infected region are reduced to different degrees. Besides, the bilobalide composition is further capable of reducing the expression of TNF-alpha and IL-2 in a dose-dependentmanner. Therefore, the experiment proves that the bilobalide composition is capable of treating / preventing Japanese encephalitis.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to the application of a ginkgolide composition in preventing / treating Japanese encephalitis. Background technique [0002] Japanese encephalitis virus (JEV) is the pathogen of Japanese encephalitis, first discovered in Japan in 1870, also known as Japanese encephalitis virus. JE is a zoonotic natural foci disease, and it is the main viral encephalitis in Pacific countries. The third generation of Culex rhinorrhea is the main vector. When the immunity is weak, the virus can destroy the blood-brain barrier and invade the central nervous system, showing symptoms such as high fever, convulsions, convulsions, disturbance of consciousness and respiratory failure. Globally, about 30,000 to 50,000 people are infected every year, and 10,000 to 15,000 people die. About 5% to 20% of severe patients have neurological sequelae. According to the report of the Ministry of Health, in 2015, a to...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/365A61P31/14
CPCA61K31/365Y02A50/30
Inventor 萧伟李良王振中刘秋许治良周军周建明章晨峰王团结胡晗绯
Owner JIANGSU KANION PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com