Stomach cleaning combined reagent used for gastroenterology department and preparation method thereof

Abstract

The invention discloses a stomach cleaning combined reagent used for the gastroenterology department. The stomach cleaning combined reagent comprises the following ingredients in parts by weight: 10-20 parts of panax notoginseng, 3-9 parts of radix astragali, 5-15 parts of radix codonopsis, 10-15 parts of Mangnolia officinalis, 8-12 parts of radix glycyrrhizae, 5-15 parts of rhizoma corydalis, 12-20 parts of cistanche salsa, 10-15 parts of bitter gourds, 3-8 parts of honeysuckles, 5-10 parts of endothelium corneum gigeriae galli, 8-10 parts of chrysanthemums, 5-10 parts of fructus forsythia, 3-7 parts of royal jelly, 2-8 parts of honey, 5-10 parts of rhizoma cyperi, 5-15 parts of fresh ginger, 10-15 parts of barleys, 50-100 parts of normal saline and 50-100 parts of 10% potassium chloride.Compared with the prior art, the stomach cleaning combined reagent has the beneficial effects that the incidence rate of complications, that is the incidence rate of hyponatremia and hypokalemia in astomach cleaning process can be reduced; meanwhile, the stomach cleaning combined reagent has an effect of nursing a stomach and is beneficial to later recovery of the stomach.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a stomach cleaning combination medicament for gastroenterology and a preparation method thereof. Background technique [0002] Gastric lavage refers to pouring a certain composition of liquid into the gastric cavity, mixing the contents of the stomach and then drawing it out, and repeating this many times. Its purpose is to remove unabsorbed poison in the stomach or clean the gastric cavity, and it is clinically used for gastric surgery and preparation before examination. For acute poisoning, such as swallowing organic phosphorus, inorganic phosphorus, alkaloids, barbiturates, etc. within a short period of time, gastric lavage is an important rescue measure. Clinically commonly used gastric lavage solution is 37 ℃ ~ 40 ℃ warm water, 1:5000 potassium permanganate and 2% sodium bicarbonate and so on. Among them, 2% sodium bicarbonate is often used for organophosphoru...

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Problems solved by technology

Among them, 2% sodium bicarbonate is often used for organophosphorus pesticide poisoning, not for trichlorfon, salicylate and strong acid poisoning; 1:5000 potassium permanganate has oxidative and detoxifying effects on alkaloids and muscarines , but contraindicated in gastric lavage for parathion poisoning

Warm boiled water at 37°C to 40°C is widely used, but when gastric lavage with warm boiled water is used, a large amount of clear water enters the gastrointestinal tract in a short period of time, resulting in a large amount of water absorption, a significant increase in the amount of extracellular fluid, a decrease in plasma osmotic pressure, and water from the cells. This is one of the causes of hypokalemia and hyponatremia; another reason is that the nausea, vomiting, and loss of fasting occurred after the patient was poisoned. Sodium and potassium are lost; and clinically, diuretics are used to accelerate the loss of sodium and potassium; in a state of stress during poisoning, abnormal secretion of antidiuretic hormone causes water and sodium retention, resulting in dilutional hyponatremia and hypokalemia

Hyponatremia and hypokalemia will cause listlessness, drowsiness, weakness of limbs, pale complexion, nausea, vomiting and other symptoms that are easily regarded as poisoning provinces, so it is easy to miss diagnosis. Serum myocardial enzymes will show CK elevation, and sometimes Misdiagnosis, affecting treatment effect

[0003] Moreover, due to the need to insert a gastric lavage tube into the stomach during gastric lavage, and repeated cleaning, it is easy to cause damage to the gastric mucosa, etc., so there is an urgent need for a device that has a wide range of applications, can balance gastric electrolytes, and has nursing and recuperative effects on the stomach. stomach wash

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