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Allergy and Congestion Relief composition and preparation method thereof

A technology of bulorenine tablets and compositions, which is applied in the field of medicine and achieves the effects of complete dissolution, good product stability, and simple and easy production operation.

Inactive Publication Date: 2018-04-20
长春海悦药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, ephedrines are precursor chemicals

Method used

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  • Allergy and Congestion Relief composition and preparation method thereof
  • Allergy and Congestion Relief composition and preparation method thereof
  • Allergy and Congestion Relief composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] prescription

[0071]

[0072] Preparation

[0073] (1) Pass ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, lanine, instant sorbitol, lubricant, and disintegrant through a 100-mesh sieve respectively, and set aside;

[0074] (2) Mix ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, lanine, instant sorbitol, and disintegrating agent, spray adhesive while mixing, make soft material, dry , to obtain the dried particles;

[0075] (3) Lubricant was added, mixed and granulated, dried at 40°C, and compressed into tablets to obtain bronolactin-pheniramine tablets.

Embodiment 2

[0077] prescription

[0078]

[0079] Preparation

[0080] (1) Pass ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, lanine, instant sorbitol, lubricant, and disintegrant through a 100-mesh sieve respectively, and set aside;

[0081] (2) Mix ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, lanine, instant sorbitol, and disintegrating agent, spray adhesive while mixing, make soft material, dry , to obtain the dried particles;

[0082] (3) Lubricant was added, mixed and granulated, dried at 40°C, and compressed into tablets to obtain bronolactin-pheniramine tablets.

Embodiment 3

[0084] prescription

[0085]

[0086] Preparation

[0087] (1) Pass ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, lanine, instant sorbitol, lubricant, and disintegrant through a 100-mesh sieve respectively, and set aside;

[0088] (2) Mix ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, lanine, instant sorbitol, and disintegrating agent, spray adhesive while mixing, make soft material, dry , to obtain the dried particles;

[0089] (3) Lubricant was added, mixed and granulated, dried at 40°C, and compressed into tablets to obtain bronolactin-pheniramine tablets.

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PUM

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Abstract

The invention belongs to the technical field of medicine, and particularly relates to an Allergy and Congestion Relief composition and a preparation method thereof, wherein the Allergy and CongestionRelief composition contains ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, lysine, instant sorbitol, a binder, a lubricant, and a disintegrant. According to the present invention, the product has advantages of good stability, complete dissolution and good quality; and the production method has the simple and easy-performing operation, and is suitable for industrial production.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a composition of bronvirin tablets and a preparation method thereof. Background technique [0002] Influenza is clinical common disease and frequently-occurring disease. At present, the treatment of cold is still based on symptomatic treatment. Due to the diversity of cold symptoms, a single drug is often ineffective. However, compound preparations can target multiple cold symptoms at the same time and have the advantage of comprehensive control. They have gradually become mainstream products in the market. [0003] The components of common anti-cold medicines mainly include antipyretic and analgesic drugs, vasoconstrictor drugs, antihistamines, antitussive and expectorant drugs and antiviral drugs. Among them, the first choice of vasoconstrictor drugs is ephedrine drugs. However, ephedrines are precursor chemicals. The use of ephedrine compound preparations to ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K31/137A61K31/192A61K31/4402A61K47/18A61K47/10A61P11/00
CPCA61K9/2013A61K31/137A61K31/192A61K31/4402A61K2300/00
Inventor 董伟刘春梅邓雪马小涛
Owner 长春海悦药业股份有限公司
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