Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Measuring method for total cardiac glycoside content in Zhuang medicine streptocaulon griffithii

A determination method, the technology of vine sophora flavescens, applied in the field of medicine, can solve the problems that there is no detection method for the content of active ingredients, and it is difficult to comprehensively and accurately control the quality of medicinal materials, and achieve the effect of simple method, good reproducibility and stability

Pending Publication Date: 2018-01-23
PHARMA FACTORY OF GUANGXI TRADITIONAL CHINESE MEDICAL UNIV
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Fuji Sophora flavescens is included in local standards such as "Guangxi Standards of Traditional Chinese Medicinal Materials" (1990 edition), "Compilation of Quality Standards for Guangxi Zhuang Medicinal Materials (Volume I)", but the original quality standards only have simple microscopic identification, while Without a detection method for the content of active ingredients, it is difficult to comprehensively and accurately control the quality of medicinal materials

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments, so that those skilled in the art can better understand the present invention, but the present invention is not limited thereto.

[0017] Materials and Instruments

[0018] Rattan Sophora flavescens was purchased from Nanning Jingchang Traditional Chinese Medicine Pieces Co., Ltd., and the production batch number is 20160401. The digoxin reference substance was purchased from the China Institute for the Control of Pharmaceutical and Biological Products, the production batch number was 100015-200709, and the reagents used were of analytical grade.

[0019] Instrument analytical balance (ME104E), 725-type UV-visible spectrophotometer (Shanghai Sunny Hengping Scientific Instrument Co., Ltd.).

[0020] Specific steps are as follows:

[0021] Preparation of reference substance solution: Accurately weigh 10 mg of digoxin reference substance, put it in...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a measuring method for total cardiac glycoside content in Zhuang medicine streptocaulon griffithii. According to the method, color-developing agents are added into samples, thecontent of total cardiac glycoside in the streptocaulon griffithii is measured by an ultraviolet spectrophotometry after the samples develop color, test conditions include that Digoxin serves as a reference substance, alkaline picric acid solution serves as the color-developing agents, detection is performed under the wave length of 415nm, the content of the reference substance and the absorbancehave a good linear relation within the range of 0-0.08mg / ml, a regression equation y=14.968x+0.008 (r=0.9969), accuracy RSD=0.1%, average sample recovery ratio is 95.51%, RSD is 2.16% (n=6), and thetotal cardiac glycoside content in the streptocaulon griffithii is 2.07mg / g. The method is simple, rapid, accurate and good in repeatability and can be used for measuring the total cardiac glycoside content in the streptocaulon griffithii, and quality basis is provided for evaluation and control of the streptocaulon griffithii.

Description

technical field [0001] The invention relates to a method for detecting active components in vine flavescens, a strong medicinal material, specifically a method for determining the content of total cardiac glycosides in active components in vine flavescens, belonging to the technical field of medicine. Background technique [0002] Radix Streptocaulonis (RADIX STREPTOCAULONIS) is the dry root of Streptocaulonjuventas (Lour.) Merr., a plant of the Astragalus family. It is called "goubaa" in the Zhuang language. Vietnam, Myanmar, Laos, Cambodia, Malaysia and other places; aliases Guyangteng, Laoyazui, Maoqingcai, Southern Sophora flavescens, Milk Vine, Motor, Red Horse Saddle, Tiger Yinteng, Laoyazui. Its woody roots are used to treat colds and fevers, enteritis, dysentery, stomachaches, bruises, and snake bites. Vine sophora flavescens is a characteristic, bulk, and Zhuang Yao medicinal material in Guangxi. It is the main prescription of the national standard national medicin...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N21/33
Inventor 罗宇东谭安蔷吴玉强朱智德
Owner PHARMA FACTORY OF GUANGXI TRADITIONAL CHINESE MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com