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Active external essence solution with functions of diminishing inflammation, facilitating skin reparation and regeneration and whitening skin and preparation method of essence solution

A skin repair and essence technology, applied in the direction of medical preparations containing active ingredients, skin care preparations, anti-inflammatory agents, etc., can solve skin redness, suppuration or pain, pathogenic bacteria are prone to drug resistance, and skin irritation Major problems, achieve the effect of restoring skin health, promoting the formation of new epidermis, and strict compatibility

Inactive Publication Date: 2017-09-22
宁波烯谷科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, cosmetics for treating acne on the market are mostly added with chemical fungicides, hormones, astringents, anti-inflammatory agents, etc. Although they can kill bacteria or eliminate inflammation in a short period of time, they are very irritating to the skin, and long-term use will increase the burden on the skin. And it is easy to cause allergic symptoms such as skin redness, suppuration or pain, and because the pathogenic bacteria are prone to drug resistance, puberty will relapse soon, and it is easy to form epilepsy marks or pigmentation

Method used

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  • Active external essence solution with functions of diminishing inflammation, facilitating skin reparation and regeneration and whitening skin and preparation method of essence solution
  • Active external essence solution with functions of diminishing inflammation, facilitating skin reparation and regeneration and whitening skin and preparation method of essence solution
  • Active external essence solution with functions of diminishing inflammation, facilitating skin reparation and regeneration and whitening skin and preparation method of essence solution

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The preparation of embodiment 1 plant extract

[0039] (1) Wash, dry and pulverize the nine plant raw materials of Akebia vine, Angelica dahurica, Sophora japonica, Trichosanthes pollen, Nocturnal vine, Polygonum cuspidatum, Selaginella chinensis, Aloe vera and Mint, and pass through a 20-mesh sieve to obtain The powder is extracted according to steps (2)-(4) respectively;

[0040] (2) Carry out reflux extraction with 90% ethanol by volume at 80°C, the mass volume ratio of crude drug to ethanol g / mL is 1:20, reflux extraction for 4 hours, a total of 4 times, and then combine the extracts;

[0041] (3) The remaining residue is leached 3 times with hot water, 4 hours each time, the extract is combined with the extract of step (2) and then cooled to 20°C to 30°C, filtered through a 100-mesh filter cloth to obtain the filtrate;

[0042] (4) in the filtrate that step (3) obtains, add the 1,3-butanediol miscibility of the same volume as ethanol, concentrate under reduced pre...

Embodiment 2

[0045] Embodiment 2 has anti-inflammation, promotes the active external application essence of skin repair regeneration and whitening effect

[0046] 1. Formula

[0047] Calculated by weight percentage, glycerin stearate 3.5%, polydimethylsiloxane 2.0%, isononyl isononanoate 1.5%, jojoba oil 1.5%, Moroccan argan oil 1.5%, tamanu oil 4.0% , Isopropyl Myristate 1.5%, Octyl Stearate 2.5%, Linoleic Acid 1.5%, Caprylic / Capric Triglyceride 2.0%, Xanthan Gum 0.1%, Propylene Glycol 2.0%, Butylene Glycol 1.5%, Seaweed Sugar 0.5%, L-pyrrolidone sodium carboxylate 1.0%, hydrogenated castor oil 1.5%, Va palmitate 0.5%, Ve acetate 0.1%, hyaluronic acid 0.3%, the plant extract prepared in Example 1 5.0%, tobacco Amide 2.0%, preservative (phenoxyethanol) 0.1%, water make up 100%.

[0048] The hyaluronic acid consists of large molecular weight hyaluronic acid with a molecular weight of 1 800 000 to 2 200 000 Da, medium molecular weight hyaluronic acid with a molecular weight of 1 000 000 to...

experiment example 1

[0059] Anti-inflammatory activity evaluation of plant extract part in Experimental Example 1 product of the present invention

[0060] Hyaluronidase and trypsin are important enzymes in the occurrence and development of inflammation. Reducing or inhibiting the activity of these two enzymes is an effective way to prevent inflammation. This example studies the effect of the product of the present invention on hyaluronidase To illustrate the anti-inflammatory effect of the plant extract part in the product of the present invention.

[0061] Experimental group I: plant extract I, prepared according to the method of Example 1

[0062] Experimental group II: plant extract II, prepared according to the method of Example 1, the difference is that it does not contain Akebia extract

[0063] Experimental group II: Akebia extract, prepared according to the method in Example 1

[0064] The above plant extracts were dissolved by adding 10 times the weight of distilled water, and prepared...

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Abstract

The invention discloses an active externally applied essence with the functions of anti-inflammation, promoting skin repair and regeneration and whitening and a preparation method thereof. The cosmetic preparation of the present invention contains natural plant extract components, and the plant extracts are composed of Akebia extract, Angelica dahurica extract, Sophora japonica extract, Trichosanthes extract, Nocturna vine extract, Polygonum cuspidatum extract, Jiangnan roll Cypress Extract, Aloe Vera Extract and Peppermint Extract. Experiments have proved that the product of the invention is safe and non-irritating to the skin, has significant anti-inflammatory effects, promotes skin repair and regeneration, and has whitening effects, thereby achieving the purpose of treating acne. The raw material of the invention is easy to obtain, the preparation method is simple and convenient, green and safe, and has good application prospect and market prospect.

Description

technical field [0001] The invention relates to an active externally applied essence and a preparation method thereof, in particular to an active externally applied essence with the functions of reducing inflammation, promoting skin repair and regeneration, and whitening and a preparation method thereof. The invention belongs to the technical field of cosmetics. Background technique [0002] Acne, also known as acne, acne or acne, is a chronic inflammatory skin disease of the pilosebaceous unit, mainly occurring in adolescents. The clinical manifestations are characterized by pleomorphic skin lesions such as acne, papules, pustules, and nodules that are prone to occur on the face. [0003] The occurrence of acne is mainly closely related to factors such as excessive sebum secretion, pilosebaceous gland duct blockage, bacterial infection and inflammatory response. After entering puberty, the level of androgen in the human body, especially testosterone, increases rapidly, wh...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61K8/9741A61K8/92A61K8/73A61K8/67A61Q19/00A61Q19/02A61K36/886A61K36/896A61P17/10A61P17/00A61P29/00
CPCA61K8/97A61K8/675A61K8/735A61K8/922A61K36/11A61K36/185A61K36/232A61K36/428A61K36/489A61K36/534A61K36/704A61K36/886A61K36/896A61K2236/333A61K2236/39A61K2236/51A61Q19/00A61Q19/02
Inventor 刘芮孜
Owner 宁波烯谷科技有限公司
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