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Traditional Chinese medicine preparation for treating gastric ulcer, and preparation method and medicinal application thereof

A traditional Chinese medicine preparation and gastric ulcer technology, applied in the field of medical applications, can solve problems affecting patient compliance, serious adverse drug reactions, gastric mucosal damage, etc., and achieve the effect of relieving abdominal pain, no toxic side effects, and fast onset

Inactive Publication Date: 2017-07-11
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) Hormone replacement drugs such as indomethacin and phenylbutazone are hormone replacement drugs, which can directly damage the gastric mucosa and cause acute gastric ulcer
(5) Anti-inflammatory drugs such as erythromycin, acetylspiramycin and other macrolide antibiotics can easily cause stomach discomfort
[0017] Because peptic ulcer is a long-term and highly recurrent disease, with the promotion of triple therapy in the treatment of Hp infection clinically, Hp drug resistance is becoming more and more serious. The adverse reactions of the drug itself are serious, which affects the patient's compliance

Method used

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  • Traditional Chinese medicine preparation for treating gastric ulcer, and preparation method and medicinal application thereof
  • Traditional Chinese medicine preparation for treating gastric ulcer, and preparation method and medicinal application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] It consists of the following raw materials in parts by weight: 20 parts of Scutellaria baicalensis, 20 parts of Radix Paeoniae Alba, 20 parts of Burnet, 20 parts of Licorice, 4 parts of Ginger, 20 parts of Bupleurum, 20 parts of Corydalis Corydalis, 1 part of Fangji, and 1 part of Red Ginseng;

[0038] The preparation method of the traditional Chinese medicine preparation for treating gastric ulcer, the specific steps are as follows: Weigh each raw medicinal material according to the weight part; grind red ginseng and Fangji into fine powder respectively; Inside, add 3 times the amount of water and decoct twice, each time for 2 hours, filter the decoction, combine the filtrates, concentrate to a relative density of 1.05-1.10 (60°C); add 5 times the amount of 75% ethanol, stir well, and let stand , filtered, and the ethanol was recovered from the filtrate, concentrated to an appropriate amount to obtain a thick paste. The thick paste is mixed with the above powder and an...

Embodiment 2

[0041] It consists of the following raw materials in parts by weight: 25 parts of Scutellaria baicalensis, 25 parts of Radix Paeoniae Alba, 25 parts of Burnet, 5 parts of Licorice, 5 parts of Ginger, 25 parts of Bupleurum, 25 parts of Corydalis Corydalis, 1.5 parts of Fangji, and 1.5 parts of Red Ginseng;

[0042] The preparation method of the traditional Chinese medicine preparation for treating gastric ulcer, the specific steps are as follows: Weigh each raw medicinal material according to the weight part; grind red ginseng and Fangji into fine powder respectively; Inside, add 3 times the amount of water and decoct twice, each time for 2 hours, filter the decoction, combine the filtrates, concentrate to a relative density of 1.05-1.10 (60°C); add 5 times the amount of 75% ethanol, stir well, and let stand , filtered, and the ethanol was recovered from the filtrate, concentrated to an appropriate amount to obtain a thick paste. The thick paste is mixed with the above powder a...

Embodiment 3

[0045] It consists of the following raw materials in parts by weight: 30 parts of Scutellaria baicalensis, 30 parts of Radix Paeoniae Alba, 30 parts of Burnet, 30 parts of Licorice, 6 parts of Ginger, 30 parts of Bupleurum, 30 parts of Corydalis Corydalis, 2 parts of Fangji, and 2 parts of Red Ginseng;

[0046] The preparation method of the traditional Chinese medicine preparation for treating gastric ulcer, the specific steps are as follows: Weigh each raw medicinal material according to the weight part; grind red ginseng and Fangji into fine powder respectively; Inside, add 3 times the amount of water and decoct twice, each time for 2 hours, filter the decoction, combine the filtrates, concentrate to a relative density of 1.05-1.10 (60°C); add 5 times the amount of 75% ethanol, stir well, and let stand , filtered, and the ethanol was recovered from the filtrate, concentrated to an appropriate amount to obtain a thick paste. The thick ointment is mixed with the above powder a...

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating gastric ulcer and a preparation method and medicinal application thereof, belonging to the field of medical technology. The traditional Chinese medicine preparation comprises 20 to 30 parts of root of large-flowered skullcap, 20 to 30 parts of white peony root, 20 to 30 parts of garden burnet, 20 to 30 parts of licorice root, 4 to 6 parts of ginger, 20 to 30 parts of Radix Bupleuri, 20 to 30 parts of corydalis tuber, 1 to 2 parts of root of fangji and 1 to 2 parts of red ginseng. The traditional Chinese medicine preparation provided by the invention has the advantages of fast action, definite therapeutic effect, high security and simple medication through synergism of bulk drugs; the preparation method is simple and friendly to environment; and the traditional Chinese medicine preparation can effectively alleviate symptoms like abdominal pain, sour regurgitation, heart burnt, swelling of the upper abdomen, nausea, vomiting and anorexia caused by gastric ulcer, is free of toxic and side effect and provides a novel option for clinical alleviation of a variety of symptoms caused by gastric ulcer.

Description

technical field [0001] The invention relates to the technical field of medical application, in particular to a traditional Chinese medicine preparation for treating gastric ulcer and its preparation method and application. Background technique [0002] Ulcer disease or peptic ulcer is a common digestive tract disease that can occur in the esophagus, stomach or duodenum, and can also occur near the gastro-jejunum anastomosis or in Meckel's diverticulum containing gastric mucosa, because gastric ulcer and Duodenal ulcer is the most common, so the so-called peptic ulcer generally refers to gastric ulcer and duodenal ulcer. [0003] The reason why it is called peptic ulcer is that gastric ulcer and duodenal ulcer were previously thought to be formed due to gastric acid and pepsin digesting the mucosa itself. In fact, gastric acid and pepsin are only one of the main causes of ulcer formation. There are other reasons why peptic ulcers can form. Because the etiology and clinical ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/48A61K47/36A61P1/04
CPCA61K36/9068A61K9/4866A61K36/233A61K36/258A61K36/484A61K36/539A61K36/59A61K36/65A61K36/66A61K36/71A61K36/739A61K2236/331A61K2236/39A61K2236/51A61K2236/53
Inventor 王丹郑炳珍祁增刘传贵王放刘金平
Owner JILIN UNIV
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