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Manufacturing method of fermented ginseng or fermented black-red ginseng extract containing active ginsenoside with improved absorption rate

A technology for fermenting ginseng and a manufacturing method, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, can solve problems such as difficult direct food use and difficult utilization, and achieve the effect of inhibiting anti-cancer and improving anti-fatigue. , the effect of inhibiting cancer metastasis

Inactive Publication Date: 2017-06-09
KOREA BLACK RED JINSENG AGRI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, when producing ginseng extracts with high ginsenoside Rg3 and 20-ginsenoside Rg3 content in the past, the generation of carcinogens such as HMF (hydroxylmethylfurfual) generated during heat treatment cannot be avoided. According to the heat and / or acid treatment process, it is necessary to After the neutralization process, the extraction and refining process needs to be performed separately, so there is a problem that it is not easy to use as a direct food
[0010] In addition, most microorganisms used for bioconverting ginsenosides include inedible Pediococcus sp., Leuconostoc sp., Aspergillus sp., Eubacterium sp. (Eubacterium sp.), Fusobacterium sp. or Bacteroides sp. strains, etc., need to perform ultrafiltration or separation and purification (extraction and purification) process for the metabolites generated thereby, so it is difficult to As a direct food, there is a problem that it is difficult to use in real life

Method used

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  • Manufacturing method of fermented ginseng or fermented black-red ginseng extract containing active ginsenoside with improved absorption rate

Examples

Experimental program
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Effect test

Embodiment 1

[0065] Manufacturing method of fermented black red ginseng extract

[0066] Select ginseng with roots more than 4 years old as raw material ginseng and clean it.

[0067] The raw ginseng is dried to make the moisture content in the ginseng less than 14%.

[0068] Put the dry water formed by the drying into an airtight container and keep 1.0ⅹ10 6 High pressure state of Pa. At this time, water was injected to such an extent that the dried ginseng was not submerged. Then, after heating for a period of 10 hours while maintaining a temperature of 125° C., black red ginseng was formed.

[0069] Then, put the formed black and red ginseng into a pulverizer, pulverize for the first time to particles with a size of 46 μm to 74 μm, put the pulverized material for the first time into an ACM pulverizer, and pulverize for the second time to particles with a size of 13 μm to 23 μm, The second pulverization is put into a polyurethane-coated dry or wet ball mill, and the third pulverizat...

Embodiment 2

[0074] Manufacturing method of fermented American black red ginseng extract

[0075]American ginseng (American ginseng) was used instead of Korean ginseng, and American black red ginseng was produced in the same manner as in Example 1, except that Enterococcus faecalis was used instead of Enterococcus faecium, and the same method as in Example 1 was used. 1 In the same way, American black red ginseng was fermented to produce fermented American black red ginseng.

Embodiment 3

[0077] Manufacturing method of fermented bamboo black red ginseng extract

[0078] Using bamboo ginseng instead of Korean ginseng, after producing bamboo black red ginseng in the same way as in Example 1, except that Enterococcus lactis was used instead of Enterococcus faecium, the same method as in Example 1 was used. Methods Fermented bamboo black red ginseng was produced.

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Abstract

The invention provides a manufacturing method of fermented ginseng or fermented black-red ginseng extract containing active ginsenoside with an improved absorption rate and a black-red ginseng product. The manufacturing method comprises the following steps: step one, grinding ginseng or black-red ginseng, and preparing nano ginseng or black-red ginseng powder; step two, adding water into nano ginseng or black-red ginseng powder, sterilizing the solution, inoculating lactobacillus into the solution; step three, culturing lactobacillus to ferment the nano ginseng or black-red ginseng powder; step four, subjecting the culture solution obtained in the step three to an aging treatment; and step five, sterilizing the aged solution obtained in the step four. The provided method can obtain fermented ginseng and black-red ginseng containing active ginsenosides (Rg2, Rh1, Rg3, and 20-ginsenoside Rg3). The lactobacillus fermentation and low temperature aging method can improve the content of ginsenoside Rg3 and 20-ginsenoside Rg3 having the advantages of relieving fatigue and preventing cancer and cancer metastasis. The steps such as neutralization, extraction, and refining are not needed, and thus the technology is simplified. The fermented ginseng and fermented black-red ginseng can be used to produce food, cosmetics, and medicines.

Description

technical field [0001] The present invention relates to fermented ginseng or fermented black red ginseng extract, and more specifically, relates to a method for producing fermented ginseng or fermented black red ginseng extract containing active ginsenosides that enhance the absorption rate in vivo. Background technique [0002] Ginseng is a perennial perennial grass belonging to the Araliaceae Panax genus in plant taxonomy. There are about 11 species known on the earth. The representative varieties are Korean ginseng (Panax ginseng C.A.Meyer), American ginseng (Panaxquinquefolium L.), (Panaxnotoginseng F.H.Chen), bamboo ginseng (Panaxjaponicus C.A.Meyer). Korean ginseng (Panax ginseng C.A. Meyer) naturally grows in the Far East of Asia (33-48 north latitude, South Korea, northeastern China, and part of Russia), and has excellent medicinal effects. American ginseng (Panaxquinquefolium L.) grows and is cultivated naturally in the United States and Canada, and Tianqi ginseng ...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61P39/00A61P35/04A61P35/00
CPCA61K36/258A61K2236/19
Inventor 李昌远
Owner KOREA BLACK RED JINSENG AGRI CO LTD
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