Macleaya cordata-scutellaria baicalensis composition for veterinary drugs or drug feed additives and application of macleaya cordata-scutellaria baicalensis composition
A feed additive, Boluohui technology, which is applied in the field of Boluohui, can solve the problems of animal autoimmunity decline, pathogenic adaptive variation, bacterial drug resistance increase, etc., and achieve the improvement of animal growth performance, small side effects, and easy access Effect
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Embodiment 1
[0040] In this experiment, the powder of the above-ground non-fruit parts of Rhizoma baicalensis (including the above-ground parts of Rhizoma rhizomes before flowering and the non-fruit parts of Rhizoma baicalensis after flowering) or its extracts were combined with Scutellaria baicalensis powder or its extracts. Recipe, then measure the content of N-p-coumaryl tyramide and baicalin in its composition, the ratio and content range of each composition are shown in the following table 1
[0041] Table 1 The content ranges of N-p-coumaryl tyramide and baicalin in each composition
[0042]
Embodiment 2
[0044] In vitro inhibition test of Boluohui extract, Scutellaria baicalensis extract and Boluohui-Scutellaria baicalensis combination extract on common pathogenic bacteria in livestock and poultry.
[0045] Choose Boluohui extract (N-p-coumaryl tyramide 0.01%), Scutellaria baicalensis extract (baicalin 1%) and Boluohui-scutellaria baicalensis extract (N-p-coumaryl tyramide 0.01%, baicalin 1%) , the extract was prepared into a solution of equal concentration, and then the in vitro antibacterial tests were carried out on common animal pathogenic bacteria such as Staphylococcus gallinarum, Salmonella pullorum, Salmonella choleraesuis, Escherichia coli and Staphylococcus aureus. According to the aseptic operation procedure, under aseptic conditions, dump the medium plate corresponding to the corresponding strain, and apply the corresponding strain inoculum on it. Paper and tablet are tightly bonded. Three copies of each sample were made, and the results were averaged. Invert cul...
Embodiment 3
[0055] Effect of Boluohui-Scutellaria baicalensis group extract (0.01% N-p-coumaryl tyramide, 1% baicalin) on diarrhea in mice induced by Escherichia coli
[0056] 40 ICR mice, half male and half male, were randomly divided into 5 groups according to sex and body weight, 8 mice in each group, respectively model control group, sulfasalazine group, Boluohui-Scutellaria baicalensis extract low, medium, and In the high-dose group, the mice in each group were intragastrically administered the corresponding drug solution at 0.2mL / 10g, once a day, for 3 consecutive days, and the mice in the model control group were intragastrically administered an equal volume of 0.5% CMC-Na . 30 minutes before the last administration, mice in each group were injected intraperitoneally with 0.6 mL / only 6×10 9 coli solution per mL, observed continuously for 4 hours after injection, and recorded the time of the first loose stool after intraperitoneal injection of Escherichia coli, the diarrhea rate an...
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