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Material distributed control platform and control method based on optical flow vortex array

A technology of distributed control and control methods, applied in chemical instruments and methods, laboratory containers, laboratory stools/laboratory benches, etc., can solve problems such as limited scope of action and distributed capture of difficult materials, and achieve application Wide range of occasions, low cost and simple system architecture

Active Publication Date: 2019-02-26
SOUTH CHINA NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, using one laser beam for excitation can only control the material located in the laser spot, and the range of action is limited. If you want to capture materials in multiple areas at the same time, you need to use multiple laser beams, which also means more experimental equipment and operations. To be done
Therefore, the current laser optical tweezers technology is difficult to realize the distributed capture of materials.

Method used

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  • Material distributed control platform and control method based on optical flow vortex array
  • Material distributed control platform and control method based on optical flow vortex array
  • Material distributed control platform and control method based on optical flow vortex array

Examples

Experimental program
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Effect test

Embodiment 1

[0057] This embodiment shows a distributed optical flow capture technology based on an optical flow vortex array. Such as image 3 As shown in a, the micro-nano material near the vortex will be affected by two forces. The first force is viscous force, whose direction is along the direction of the vortex flow, and the second force is the lift force, whose direction is perpendicular to the direction of the vortex flow and points to the vortex center. Under the action of viscous force and lift force, the micro-nano material will enter the center of the vortex in a spiral trajectory. Therefore, the center of the vortex can act as a stable point for trapping material. Maglani convection can provide four vortex centers, which means that four trapping positions can be provided, thus realizing the distributed trapping technology based on the optical flow vortex array. image 3 b-d show the overall process of vortex 1 and vortex 3 trapping two polystyrene microspheres respectively. ...

Embodiment 2

[0059] This embodiment shows the optical flow manipulation technique by tuning the power of the light source. Such as Figure 4 As shown in a, as the light input power increases, the photothermal heat source on the surface of the microfluid absorbs more light energy, releases more heat energy, and the temperature also increases. In the process, the microfluidics spread the thermal energy farther away, resulting in a wider and faster Marangoni convection. The increased range of convection affects the movement of the vortex center, which eventually guides the captured material away from the photothermal heat source. Conversely, the reduction of power can also guide the capture material closer to the photothermal heat source. Figure 4 b-d shows the experimental process of optical flow manipulation by tuning the light source power. Under the input power of 10mW, two polystyrene microspheres were captured by vortex 2 and vortex 4 respectively and stopped at the center of the vo...

Embodiment 3

[0061] This embodiment shows the optical flow manipulation technique by tuning the position of the photothermal heat source. Such as Figure 5 As shown in (a), under the control of the fine-tuning frame, the photothermal heat source moves from the old position to the new position on the microfluidic surface. The disappearance of the photothermal heat source at the old position leads to the disappearance of Marangoni convection, while the new position is due to the The appearance of photothermal heat source leads to the emergence of Marangoni convection. During this process, the center of the vortex also moves from the old position to the new position, eventually guiding the trapped material from the old position to the new position. Figure 5 (b)-(d) show the experimental process of optical flow manipulation by tuning the position of the photothermal heat source. At t=0s, under the input power of 10mW, four polystyrene microspheres were captured by vortex 1-4 respectively an...

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Abstract

The invention discloses a light stream vortex array based material distributed control platform and a control method. An optothermal heat source on the surface of a microfluid is excited to produce Marangoni convection, the Marangoni convection comprises four vortexes, each vortex rotates in a certain direction, and the speed at the center is the lowest. The center of each vortex provides a stable potential barrier used for capturing a material. Once the material is captured to the center of the vortex, the rotation flow direction of the vortex provides a torque to drive the material to rotate (clockwise or anticlockwise). The vortex array moves along with the movement of micro-nano waveguide in a chip, so that a target is controlled to move directionally in the microfluid. On the basis that particles are captured and rotated through the vortex, the various particles, biological cells and the like, which are originally scattered in the microfluid and are not mutually contacted, are captured in the same vortex through attraction, the rotation of the various materials in the vortex promotes the mutual actions of the materials, so that the materials are induced to achieve the functions of automated assembly, etc.

Description

technical field [0001] The invention belongs to the field of material manipulation, and specifically relates to a multifunctional control platform and control system based on an optical flow vortex array that realizes distributed capture, targeted manipulation, self-rotation, and automatic assembly of micro-nano materials, biological cells and their molecules, etc. method. Background technique [0002] In a microfluidic system, the capture, movement, and arrangement of various materials in fluids are the basic means for material synthesis and analysis. It has wide application value in the field of microsystem and biomedicine. In the past, the operation technology mainly realized the contact operation through the probe of the atomic force microscope. For the biochemical environment, this kind of direct contact is easy to cause mechanical damage and pollution to the sample. Therefore, the use of external equipment to stimulate various fields to realize remote operation has b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L9/02B01L3/00
CPCB01L3/5027B01L3/502707B01L9/02B01L2200/10
Inventor 邢晓波郑嘉鹏周瑞雪张俊优何赛灵杨剑鑫史可樟
Owner SOUTH CHINA NORMAL UNIVERSITY
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