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Use of turmeric extract in preparation of products used for preventing drunkenness and alleviating drunkenness and having auxiliary effect on chemical liver injury

A technology for chemical liver injury and turmeric extract, applied in the field of preparation of turmeric extract, can solve the problems of low solubility, limited application, difficulty in extracting turmeric extract and the like

Inactive Publication Date: 2017-04-26
YUNNAN BAIYAO GROUP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the difficulty of extracting turmeric extract, low solubility, poor stability and other characteristics, its application in functional health products is greatly limited, and there are no related reports on the application of turmeric extract in hangover products

Method used

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  • Use of turmeric extract in preparation of products used for preventing drunkenness and alleviating drunkenness and having auxiliary effect on chemical liver injury
  • Use of turmeric extract in preparation of products used for preventing drunkenness and alleviating drunkenness and having auxiliary effect on chemical liver injury
  • Use of turmeric extract in preparation of products used for preventing drunkenness and alleviating drunkenness and having auxiliary effect on chemical liver injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Different Components of Curcuma Longa Anti-drunk Effect Test on Mice

[0018] 1.1 Experimental animals: 100 male Kunming mice were randomly divided into 5 groups according to body weight.

[0019] 1.2 Grouping and treatment: randomly divided into model control group, turmeric (coarse powder) low-dose group, turmeric (coarse powder) high-dose group, turmeric (alcohol extract) group and turmeric (volatile oil) group, a total of 5 groups, each group 20 only.

[0020] 1.3 Implementation method: Each drug administration group was given the corresponding dosage by intragastric administration, once a day for 7 consecutive days, and the model control group was intragastrically administered the same amount of perilla seed oil. 30 minutes after the last administration, the mice in each group were given white wine (17ml / kg, obtained from the preliminary test) by intragastric administration, and the disappearance of the righting reflex of the mice was used as the indicat...

Embodiment 2

[0028] Embodiment 2: Curcuma longa (volatile oil) is to the influence of rat liver tissue alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activity

[0029] 2.1 Experimental animals: 50 male SD rats were randomly divided into 5 groups according to body weight, 10 in each group.

[0030] 2.2 Grouping and treatment: divided into normal control group (N group), model control group (M group), turmeric (volatile oil) low dose group (HF-D group), turmeric (volatile oil) medium dose group (HF-Z group) and Turmeric (volatile oil) high dose group (HF-G group). Each treatment group was intragastrically administered according to the corresponding dose, once a day for 6 consecutive days, and the normal control group and the model control group were intragastrically administered the same amount of perilla seed oil.

[0031] 2.3 Implementation method:

[0032] 30 minutes after the last administration, except the normal control group, the rats in the other groups were give...

Embodiment 3

[0037] Example 3: Study on the protective effect of turmeric (volatile oil) products on subacute alcoholic liver injury in mice

[0038] 3.1 Experimental animals and grouping: male KM mice were randomly divided into 8 groups, 15 in each group, respectively normal control group, model control group, turmeric volatile oil control group (180mg / kg), turmeric volatile oil low-dose group (9mg / kg). kg), turmeric volatile oil middle dose group (90mg / kg) and turmeric volatile oil high dose group (180mg / kg).

[0039] 3.2 Establishment of subacute alcoholic liver injury model

[0040] The mice in each group were given the test samples by oral gavage every day, and the normal control group and the model control group were given perilla seed oil, and the mice were gavaged continuously for 30 days. Animals were weighed twice weekly to adjust test sample doses. The model control group and the sample group were given 35% ethanol by oral gavage every day 14 days before the end of the experimen...

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Abstract

The invention discloses a new use of a turmeric extract in products used for preventing drunkenness and alleviating drunkenness and having auxiliary effect on chemical liver injury, and specifically relates to the use of the turmeric extract in preparation of the products used for preventing drunkenness and alleviating drunkenness and having auxiliary effect on chemical liver injury and a preparation method of the turmeric extract.

Description

technical field [0001] The invention belongs to the field of health care products, and specifically relates to the application of turmeric extract in the preparation of products with auxiliary effects for preventing drunkenness, hangover and chemical liver damage and a preparation method of turmeric extract. Background technique [0002] Turmeric (Latin name: Curcuma longa L.), aliases: tulip, Baodingxiang, millet, yellow ginger, is a perennial herb of the genus Curcuma in the Zingiberaceae family. Often used as a food additive, studies have shown that turmeric has important application value in medicine, nutrition and health care, etc., and is called "plant gold". Have blood dispelling, promoting the circulation of QI, stimulating menstruation, relieving pain. Control confidant's distending pain, arm pain, lump in the abdomen, women's blood stasis amenorrhea, postpartum abdominal pain due to blood stasis, injury from falls, carbuncle. It is used for chest and abdominal pa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16A61P39/02A23L33/105
CPCA23V2002/00A61K36/9066A61K2236/333A61K2236/37A61K2236/51A61K2236/53A23V2200/334
Inventor 王明辉朱兆云王京昆崔涛冯莉萍郭琰孙敏梅双喜苏梅王宁张天财
Owner YUNNAN BAIYAO GROUP
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