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Short wavelength laser chiral Raman spectrometer

A Raman spectrometer and short-wavelength technology, applied in the field of short-wavelength laser chiral Raman spectrometer, can solve the problem that chiral Raman spectroscopy is easily interfered by fluorescence, research on Raman optical activity of difficult chiral samples, and chiral Raman spectroscopy Problems such as low signal sensitivity

Active Publication Date: 2017-03-29
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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Problems solved by technology

Chiral Raman spectroscopy is susceptible to fluorescence interference, and the sensitivity of chiral Raman spectroscopy signals is very low, making it difficult to study the Raman optical activity of chiral samples at low concentrations

Method used

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Embodiment 1

[0016] as attached figure 1 As shown, a short-wavelength laser chiral Raman spectrometer (short-wavelength laser Raman optical activity spectrometer), consists of a laser excitation light source with a wavelength between 325nm and 532nm, a linearly polarized light uniform system, a circularly polarized light converter, and a sample Pool, circular polarized light splitter, double-beam bifurcated fiber, Rayleigh line filter, imaging spectrometer, charge-coupled device short-wavelength wide-range sensitive CCD, and computer.

[0017] The excitation light source is mainly composed of DPSS lasers with different wavelengths. The output power of the 457nm laser is greater than 300mW, and the output power of the 532nm laser is greater than 1000mW. The output power and mode are stable, meeting the needs of chiral Raman spectroscopy.

[0018] The laser light emitted by the short-wavelength laser passes through the linearly polarized uniform system, and after being collimated and focuse...

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Abstract

The invention relates to a short wavelength laser chiral Raman spectrometer, which comprises a laser excitation light source having a wavelength of 325-532 nm, a linearly polarized light uniformization system, a circularly polarized light converter, a sample pool, a circularly polarized light separator, double light beam forking optical fiber, a Rayleigh line filter, an imaging spectrometer, a short-wavelength, wide-range and sensitive charge coupled device (CCD), and a computer. According to the present invention, the short wavelength laser chiral Raman spectrometer is used for the determination of the chiral absolute configuration of chiral molecules and biomolecules, and is the powerful tool for the absolute configuration and conformation analysis of the chiral molecules in the fields of chemistry, biologly, and medicine.

Description

technical field [0001] A short-wavelength laser chiral Raman spectrometer (short-wavelength laser Raman optical activity spectrometer), consisting of a laser excitation light source with a wavelength between 325nm and 532nm, a linearly polarized light uniform system, a circularly polarized light converter, a sample cell, and a circular It is composed of polarized light separator, double-beam bifurcated optical fiber, Rayleigh line filter, imaging spectrometer, charge-coupled device, CCD with short wavelength and wide range sensitivity, and computer. The short-wavelength chiral Raman spectrometer can be used for chiral Raman spectroscopy of gas, liquid and solid samples, namely Raman optical activity spectroscopy, to obtain information on their absolute configuration and conformation. Background technique [0002] The chiral Raman spectrometer, that is, the Raman optical activity spectrometer, determines the chiral Raman signal, that is, the Raman optical activity signal, thr...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65
CPCG01N21/65G01J3/44G01N21/21G01N2021/216G01J3/10G01J2003/104G01J3/0224G01J3/0218
Inventor 李灿冯兆池王鹏张莹唐宇轩
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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