Inactivated type lactic acid bacteria microecological preparation as well as preparation method and application thereof

Abstract

The invention relates to an inactivated type lactic acid bacteria microecological preparation as well as a preparation method and application thereof. The inactivated type lactic acid bacteria microecological preparation comprises inactivated bacteria and auxiliary materials, wherein the inactivated bacteria comprise inactivated bifidobacteria and inactivated bacterium lacticum. The inactivated microecological preparation disclosed by the invention is high in safety, resistant to infection by bacteriophages, free from limit of bacterium quantity, and high in product quality stability, and can be matched with an antibiotic for use; besides, the inactivated type lactic acid bacteria have the efficient capacity of being adhered to epithelial cells of intestinal tracts, and are resistant to high temperature, high acid and bile; when the inactivated type lactic acid bacteria and the antibiotic are in synergic use, the problems of a viable bacteria preparation can be safely and effectively solved; and in addition, the inactivated lactic acid bacteria can generate competitive inhibition on harmful microorganisms, adsorb harmful substances and regulate an immune response reaction, so that the immunity of organisms can be enhanced. The preparation method disclosed by the invention has the characteristics of being simple to operate and mild in conditions, and cost reduction, popularization and production are facilitated.

Description

technical field [0001] The invention relates to the technical field of probiotics, in particular to an inactivated lactic acid bacteria probiotic and its preparation method and application. Background technique [0002] Microecological preparations are living microbial preparations made from normal microorganisms or substances that promote the growth of microorganisms. That is to say, all preparations that can promote the growth and reproduction of normal microflora and inhibit the growth and reproduction of pathogenic bacteria are called "microecological preparations". Its main component, probiotics, is a type of active microorganisms that are beneficial to the host. They are active beneficial microorganisms that colonize the human intestinal tract and reproductive system and can produce definite health effects, thereby improving the host's micro-ecological balance and exerting beneficial effects. Probiotics can help the human body maintain and regulate the balance of inte...

AI Technical Summary

Problems solved by technology

[0003] At present, probiotic preparations are often easily affected by environmental factors such as production and transportation, resulting in loss of vitality, and live bacterial preparations cannot effectively resist the influence of gastric acid and bile salts after entering the digestive tract, and cannot be colonized for a long time to exert their effects

Moreover, the existing probiotic preparations have a single active ingredient, and long-term use can easily lead to an increased risk of phage infection and outbreaks