A kind of liquid gel and preparation method thereof
A gel and liquid technology, used in liquid delivery, pharmaceutical formulations, emulsion delivery, etc., can solve the problems of ineffective relief, imbalance of vaginal flora, and insignificant curative effect, and achieves improvement of vaginal cleanliness and reduction of vaginal pH value. , the effect of reducing the amount of vaginal secretions
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Embodiment 1
[0017] The composition of the gel comprises: 2 parts by weight of chitosan, 2 parts by weight of hypromellose, 2 parts by weight of polyethylene glycol 6000, 0.2 part by weight of chlorhexidine acetate, 0.15 parts by weight of carbomer, and 0.15 parts by weight of propylene glycol 2 parts by weight of hawthorn core, 1.5 parts by weight of hyaluronic acid, 0.02 part by weight of miconazole nitrate, 55 parts by weight of purified water, and a pH value of 6.5.
[0018] Specific steps include:
[0019] (1) Dissolve chitosan in purified water according to the formula ratio, and wait for use after fully swelling;
[0020] (2) Dissolve hyaluronic acid substances in purified water according to the formula ratio, fully swell and set aside;
[0021] (3) Mix the remaining other components in the formula ratio evenly;
[0022] (4) Add the solution obtained in steps (1)-(3) into the same container, stir and mix well, and adjust the pH value to obtain a gel product.
[0023] The sum of t...
Embodiment 2
[0025] The composition of the gel comprises: 1.5 parts by weight of chitosan, 1 part by weight of hypromellose, 1 part by weight of polyethylene glycol 6000, 0.2 parts by weight of chlorhexidine acetate, 0.3 parts by weight of carbomer, and 0.8 parts by weight of propylene glycol 1 part by weight of hawthorn core, 1 part by weight of hyaluronic acid, 0.025 part by weight of miconazole nitrate, 60 parts by weight of purified water, and a pH value of 77.
[0026] Method is with embodiment 1.
Embodiment 3
[0028] The composition of the gel comprises: 2 parts by weight of chitosan, 3 parts by weight of hypromellose, 2.5 parts by weight of polyethylene glycol 6000, 0.20 parts by weight of chlorhexidine acetate, 0.20 parts by weight of carbomer, and 0.6 parts by weight of propylene glycol Parts, 0.6 parts by weight of hawthorn core, 1.0 parts by weight of hyaluronic acid substances, 0.05 parts by weight of miconazole nitrate, 55 parts by weight of purified water, pH value 6.
[0029] Method is with embodiment 1.
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