Liquid bandage containing povidone iodine and preparation method thereof
A liquid band-aid, povidone-iodine technology, applied in medical science, bandages, absorbent pads, etc., to achieve good bactericidal and bacteriostatic effects, promote wound healing, and have no allergic reactions and drug resistance.
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Embodiment 1
[0048]
[0049] The preparation method is as follows:
[0050] 1. Mix the prescribed amount of polyvinyl butyral, glycerin, menthol, ethyl acetate, and 95% ethanol evenly, and stir for 1 hour at room temperature with a stirrer at a rotation speed of 800 rpm to prepare a mixed solution A.
[0051] 2. Mix the povidone-iodine, 30% hydrogen peroxide and purified water evenly in the prescribed amount, and stir for 15 minutes at room temperature under a stirrer with a rotating speed of 500 rpm to fully dissolve the povidone-iodine. Then add chitosan, and continue to stir at room temperature under a stirrer with a rotating speed of 800 rpm for 45 minutes, so that the chitosan is completely dissolved, and mixed solution B is made.
[0052] 3. Mix the solutions A and B evenly, stir for 15 minutes at room temperature under a stirrer with a rotating speed of 500 rpm, and adjust the pH to 3.0-4.0 to form a liquid wound dressing containing 10% povidone-iodine.
Embodiment 2
[0054]
[0055]
[0056] The preparation method is as follows:
[0057] 1. Mix the prescribed amount of vinylpyrrolidone / vinyl acetate copolymer, glycerin, menthol, ethyl acetate, and 75% ethanol evenly, and stir for 1 hour at room temperature with a stirrer at a speed of 800 rpm to form a mixed Solution A.
[0058] 2. Mix the povidone-iodine, 30% hydrogen peroxide and purified water evenly in the prescribed amount, and stir for 15 minutes at room temperature under a stirrer with a rotating speed of 500 rpm to fully dissolve the povidone-iodine. Then add chitosan, and continue to stir at room temperature under a stirrer with a rotating speed of 800 rpm for 30 minutes, so that the chitosan is completely dissolved, and mixed solution B is made.
[0059] 3. Mix solutions A and B evenly, stir for 15 minutes at room temperature under a stirrer with a rotating speed of 500 rpm, adjust the pH to 3.0-4.0, and then prepare a liquid wound dressing containing 5% povidone-iodine. ...
Embodiment 3
[0061]
[0062]
[0063] Preparation process with reference to embodiment 2
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