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Calcium carbonate vitamin C effervescent tablet with good effervescent effect and making method of effervescent tablet

A production method and technology of calcium carbonate are applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., and can solve the problems of discoloration, effervescent effect, bag swelling, inedible, etc.

Active Publication Date: 2016-11-23
贵州汉方药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to treat osteoporosis and other diseases, there are many effervescent tablets made of vitamin C as the main raw material on the market. However, when the existing effervescent tablets are made, the process parameters are not very reasonable, which makes the effervescent tablets made stable. No, it is prone to problems such as bag swelling, discoloration and effervescent effect decay after listing
In addition, the existing effervescent tablets made of vitamin C also contain sugar, pigments, flavors, etc.
It cannot be eaten by diabetics who need to supplement vitamin C and calcium, and most of the pigments and flavors are chemical additives, which are harmful to health

Method used

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  • Calcium carbonate vitamin C effervescent tablet with good effervescent effect and making method of effervescent tablet
  • Calcium carbonate vitamin C effervescent tablet with good effervescent effect and making method of effervescent tablet
  • Calcium carbonate vitamin C effervescent tablet with good effervescent effect and making method of effervescent tablet

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0130] Formula: vitamin C 1000g, calcium carbonate 250g, mannitol 1100g, anhydrous citric acid 1000g, sodium bicarbonate 600g, cyclamate 156g, leucine 125g.

[0131] Process: It includes the following steps: in an environment with a temperature of 18-26°C and a relative humidity below 45%, dry the silica gel particles at 100°C for 5 hours and seal them, and let them cool to room temperature. Mixed, airtight, dried at 40°C for 18 hours, sieved to remove silica gel particles, obtained. The prepared sodium bicarbonate is ready for use; vitamin C, citric acid, calcium carbonate, leucine, and cyclamate are respectively dried for 2 hours at a vacuum degree of >0.87Mmpa and a temperature of 40°C, sealed, and placed at room temperature. The prepared vitamin C, citric acid, calcium carbonate, leucine, and cyclamate are sealed and reserved; the prepared sodium bicarbonate and the prepared vitamin C, calcium carbonate, mannitol, anhydrous citric acid, and cyclamate Mix evenly, dry granu...

experiment example 2

[0134] Formula: vitamin C 800g, calcium carbonate 300g, mannitol 900g, anhydrous citric acid 800g, sodium bicarbonate 500g, cyclamate 100g, leucine 100g.

[0135] Manufacturing process: with embodiment 1.

[0136] Usage is the same as embodiment 1.

experiment example 3

[0138]Formula: vitamin C 1200g, calcium carbonate 400g, mannitol 1300g, anhydrous citric acid 1200g, sodium bicarbonate 700g, cyclamate 200g, leucine 150g.

[0139] Manufacturing process: with embodiment 1.

[0140] Usage is the same as embodiment 1.

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PUM

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Abstract

The invention discloses a calcium carbonate vitamin C effervescent tablet with a good effervescent effect and a making method of the effervescent tablet. The effervescent tablet is prepared from vitamin C, calcium carbonate, mannitol, anhydrous citric acid, sodium bicarbonate, sodium cyclamate and leucine. The prepared effervescent tablet is sour, sweet, delicious, good in effervescent effect, wide in applicable crowd, free from sugar, pigments and essence, suitable for diabetic patients and harmless to fitness, and effervesced solution is clear.

Description

Field of invention: [0001] The invention relates to a calcium carbonate vitamin C effervescent tablet with good effervescent effect and a preparation method thereof, belonging to the technical field of medicines. technical background: [0002] Vitamin C is an essential vitamin for the body that supports the body's defense system. Everyone cannot lack vitamin C, especially smokers, athletes, pregnant and lactating women need to increase vitamin C supplements. Calcium is an essential element for living organisms. For the human body, Ca is available in muscles, nerves, body fluids and bones 2 + bound protein. Calcium is the main inorganic component of human bones and teeth, and is also an essential element for nerve transmission, muscle contraction, blood clotting, hormone release and milk secretion. Calcium accounts for about 1.4% of the body's mass and participates in metabolism. Calcium must be supplemented every day; insufficient or excess calcium in the human body wil...

Claims

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Application Information

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IPC IPC(8): A61K9/46A61K33/10A61K47/26A61K47/18A61K47/02A61P19/10A61P3/02A61K31/375
CPCA61K9/0007A61K9/2009A61K9/2013A61K9/2018A61K31/375A61K33/10A61K2300/00
Inventor 张仕林杨祖发刘莉王海洋尚秘刘倩倩蒙正晴
Owner 贵州汉方药业有限公司
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