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Developing type degradable restoration pancreatic duct bracket

A pancreatic duct and contrast agent technology, applied in the field of developing degradable pancreatic duct stents, can solve the problems of inability to understand the shape and position of implanted materials, vulnerable tissue of patients, low electron density, etc., and achieve controllable degradation time. , reduce scarring, promote healing and repair effect

Pending Publication Date: 2016-10-26
青岛蓝博云健康产业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Most of these materials only contain elements with low electron density and low specific gravity, such as C, H, and O, and cannot be detected by X-rays, which makes it impossible for medical personnel to understand the specific shape and position of implanted materials in the body, and cannot place them accurately. At the lesion site, the patient's tissue is also vulnerable to injury, which brings difficulties to the operation. Therefore, the development-type degradable repair pancreatic duct stent is a current research hotspot. The contrast agents mainly include barium and iodine. Barium is mainly used for Esophagus and gastrointestinal contrast, while iodine is mainly used for contrast of bile duct and gallbladder, renal pelvis and urinary tract, arteries and veins

Method used

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  • Developing type degradable restoration pancreatic duct bracket

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Example 1 Preparation method of developing-type degradable repair of pancreatic duct

[0058] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0059] Cooling: cooling by air cooling.

[0060] Guachuang coating: through automatic dispensing machine and other equipment, glue is applied to the spiral groove of the outer wall of the threaded pipe, dried, washed with absolute ethanol, dried, and the healing and repairing functional material is a colloid solution made of polysaccharide .

[0061] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acyl...

Embodiment 2

[0069] Example 2 Preparation method of developing-type degradable repair of pancreatic duct

[0070] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0071] Cooling: cooling by air cooling.

[0072] Guachuang coating: through automatic dispensing machine and other equipment, glue is applied to the spiral groove of the outer wall of the threaded pipe, dried, washed with absolute ethanol, dried, and the healing and repairing functional material is a colloid solution made of polysaccharide .

[0073] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acyl...

Embodiment 3

[0081] Example 3 Preparation method of developing-type degradable repair of pancreatic duct

[0082] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0083] Cooling: cooling by air cooling.

[0084] Guachuang coating: through automatic dispensing machine and other equipment, glue is applied to the spiral groove of the outer wall of the threaded pipe, dried, washed with absolute ethanol, dried, and the healing and repairing functional material is a colloid solution made of polysaccharide .

[0085] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acyl...

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Abstract

The invention relates to a developing type degradable restoration pancreatic duct bracket, which is prepared from the following ingredients including 50 to 100 weight parts of degradable medical materials A, 0.1 to 50 weight parts of heeling restoration materials B, 0.001 to 0.05 weight part of developing agents C, 0.001 to 0.05 weight part of pancreatitis treating medicine D, or 0.001 to 0.05 weight part of antitumor medicine E. The developing type degradable restoration pancreatic duct bracket has the advantages that the biocompatibility is high; the form and the position of implanting materials can be fast judged; the degrading time is controllable; and in the complicated pancreatic duct rebuilding process, the effects of pressure reduction support, drainage, pancreatic duct heeling facilitation, convenience in pancreatic juice condition observation, postoperative pancreatic ductograph and the like can be achieved.

Description

technical field [0001] The invention belongs to the field of biomedical materials, and relates to a developing-type degradable repairing pancreatic duct stent. Background technique [0002] Interventional radiology is a new branch of the field of radiology, and many of its techniques are derived from surgery, adopted and improved by radiologists. [0003] Interventional therapy comes from interventional radiology. It is an emerging treatment method between surgery and internal medicine. It uses X-ray perspective, CT positioning, B-type ultrasound equipment and other medical imaging equipment as guidance to guide special catheters or instruments through human arteries, The veins, the natural ducts of the digestive system, the pancreatic ducts, or the drainage ducts after surgery reach the lesion area in the body to obtain tissue cells, bacteria or biochemical data, and imaging data can also be obtained through radiography, so as to achieve the purpose of diagnosing the diseas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/18A61L31/16A61L31/14A61L27/54A61L27/58A61L27/50
CPCA61L31/148A61L31/16A61L31/18A61L2300/412A61L2300/416
Inventor 潘学理全志伟
Owner 青岛蓝博云健康产业发展有限公司
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