Composition of probiotic-fermented corn stigma as well as preparation method and application of composition

A technology of corn silk and a composition, applied in the field of biological fermentation, can solve the problems of not using human probiotics fermentation technology, etc., and achieve the effects of easy to accept taste, improve constipation, and increase absorption

Inactive Publication Date: 2016-10-26
SANZHU FUER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above studies and relevant literature mainly involve the use of relevant equipment or organic solvents and related enzymes for the extraction of chemical components of corn silk, pharmacological effects, and research on antioxidant activity. They do not use human probiotic fermentation technology to improve the active components of corn silk. research on efficacy

Method used

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  • Composition of probiotic-fermented corn stigma as well as preparation method and application of composition
  • Composition of probiotic-fermented corn stigma as well as preparation method and application of composition
  • Composition of probiotic-fermented corn stigma as well as preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: Preparation of composition A of probiotic fermented corn silk

[0031]Dry corn silk, crush it, pass through a 65-mesh sieve, weigh 20 g of corn silk powder, add water 15 times the weight of medicinal materials, 70 µg of sodium selenite, 155 µg of chromium trichloride hexahydrate, 100 mg of dipotassium hydrogen phosphate, and 100 mg of dihydrogen phosphate Potassium 100mg, soak for 1.0 hour, adjust the pH value to 7.0, and sterilize at 115°C for 50 minutes; when the temperature drops to 39°C, insert the pre-cultured Bifidobacterium breve (AS 1.2213) bacterial solution, and the inoculation amount is 1% ( Volume / volume), cultured at 37°C for 16 hours, then inoculated with Lactobacillus acidophilus (AS 1.1854) and Lactobacillus plantarum (AS 1.19) bacteria solution, the inoculum volume was 0.5% (volume / volume). Continue to cultivate at 37°C until the pH value of the fermentation broth is 4.0, adjust the pH value of the fermentation broth to 5.0 with sterile so...

Embodiment 2

[0032] Example 2: Preparation of Composition B of Probiotic Fermented Corn Silk

[0033] Dry the corn silk, crush it, pass it through a 80-mesh sieve, weigh 15g of the corn silk powder, add water 15 times the weight of the medicinal material, 70 µg of sodium selenite, 155 µg of chromium trichloride hexahydrate, 100 mg of dipotassium hydrogen phosphate, and 100 mg of dihydrogen phosphate Potassium 100mg, soak for 1.0 hour, adjust the pH value to 7.0, and sterilize at 115°C for 50 minutes; when the temperature drops to 39°C, insert the pre-cultured Bifidobacterium longum subsp. 1% (volume / volume), cultured at 37°C for 16 hours, then inoculated with Lactobacillus delbrueckii (AS1.1480) and Lactobacillus rhamnosus (AS1.22), the inoculum was 0.5% (volume / volume) volume). Continue to cultivate at 37°C until the pH value of the fermentation broth is 4.0, adjust the pH value of the fermentation broth to 5.0 with sterile sodium hydroxide, continue to ferment until the pH value is 4.0,...

Embodiment 3

[0034] Example 3: Preparation of Composition C of Probiotic Fermented Corn Silk

[0035] Dry the corn silk, crush it, pass through a 100-mesh sieve, weigh 25g of the corn silk powder, add water 15 times the weight of the medicinal material, 70 µg of sodium selenite, 155 µg of chromium trichloride hexahydrate, 100 mg of dipotassium hydrogen phosphate, and 100 mg of dihydrogen phosphate Potassium 100mg, soak for 1.0 hour, adjust the pH value to 7.0, and sterilize at 115°C for 50 minutes; when the temperature drops to 39°C, insert the pre-cultured Bifidobacterium adolescentis (AS 1.2190) bacterial solution, and the inoculation amount is 1% ( volume / volume), cultured at 37°C for 16 hours, then inoculated with Lactobacillus salivarius subsp. Continue to cultivate at 37°C until the pH value of the fermentation broth is 4.0, adjust the pH value of the fermentation broth to 5.0 with sterile sodium hydroxide, continue to ferment until the pH value is 4.0, adjust the fermentation temper...

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Abstract

The invention discloses a composition of probiotic-fermented corn stigma as well as a preparation method of the composition. The composition is prepared by the following steps: drying and crushing the corn stigma, soaking the corn stigma, conducting probiotic fermentation, and adding a sweetening agent. The corn stigma, through the probiotic fermentation, is relatively high in content of corn stigma total saponins and relatively low in molecular weight of corn stigma polysaccharides; and the fermented corn stigma can take such effects on lowering blood glucose, reducing blood fat, relieving swelling and inducing diuresis, clearing away heat and toxic materials, calming liver and benefiting gallbladders, improving constipation and the like. The composition of the probiotic-fermented corn stigma disclosed by the invention has easily acceptable taste and the composition is non-irritant to gastrointestinal tracts; and meanwhile, the composition, which contains probiotics and metabolites thereof, is capable of conditioning the environment of the gastrointestinal tracts and enhancing drug absorption.

Description

technical field [0001] The invention relates to a fermentation composition prepared by co-fermentation of probiotics and corn silk and its application in the field of functional health care products or medicines, belonging to the technical field of biological fermentation. technical background [0002] Corn silk (Stigma Maydis) is the style and stigma of corn. The earliest medicinal records can be found in "Southern Yunnan Wood Grass" in 1476. Approved by the Health Supervision Letter [2012] No. 306, corn silk is managed as a common food. Since the 1920s, domestic and foreign scholars have begun to study the chemical composition of corn silk, and found that corn silk contains polysaccharides, alkaloids, flavonoids, saponins, bitter glycosides, sterols, polypentose , volatile substances, amino acids, mineral elements and other chemical components have antibacterial, anti-tumor, hypoglycemic, blood lipid, diuretic, antihypertensive, and immune-enhancing effects. [0003] Cor...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K47/02A61K47/26A61P3/10A61P3/06A61P7/10A61P29/00A61P1/16A61P1/10A23L33/00
CPCA61K36/899A61K47/02A61K47/26A61K2236/19A61K2236/51A61K2236/53
Inventor 吴炳新孙筱林陆继臣褚新红
Owner SANZHU FUER PHARMA
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