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Traditional Chinese medicine ultra-micro powder granules for preventing and treating necrotic enteritis of poultry and preparation method thereof

A technology of necrotic enteritis and superfine powder, which is applied in the direction of medical formula, medical preparations containing active ingredients, and devices for making medicines into special physical or taking forms, which can solve the problem of large dosage of traditional Chinese medicine powders and inability to obtain efficacy Make full use of the problems of high cost and achieve small particle size, improve the palatability of drugs, and improve the water solubility

Inactive Publication Date: 2016-08-24
SHENYANG VICA ANIMAL HUSBANDRY TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The second object of the present invention is to provide a natural medicine powder with no drug residue, no side effects, reduced dosage, and good curative effect in order to overcome the problems of traditional Chinese medicine powders, such as large dosage, high cost, and inability to fully exert the medicinal effect. Preparation method of superfine powder granules of traditional Chinese medicine composition with significant control effect on poultry necrotic enteritis

Method used

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  • Traditional Chinese medicine ultra-micro powder granules for preventing and treating necrotic enteritis of poultry and preparation method thereof
  • Traditional Chinese medicine ultra-micro powder granules for preventing and treating necrotic enteritis of poultry and preparation method thereof
  • Traditional Chinese medicine ultra-micro powder granules for preventing and treating necrotic enteritis of poultry and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A traditional Chinese medicine composition superfine powder granule for preventing and treating poultry necrotic enteritis and a preparation method thereof, the steps are:

[0027] (1) Take the decoction pieces of various components in the prescription, grind them into 100-mesh fine powder respectively, and then pulverize them with a superfine pulverizer until the passing rate of a 500-mesh sieve is ≥ 95%, so as to obtain superfine powders of various components.

[0028] (2) Take the superfine powder of each component by weight, 120g of Andrographis paniculata, 65g of three needles, 65g of purslane, 60g of myrobalan, and 60g of Baibu, and mix for 5-15 minutes until uniform.

[0029] (3) Weigh the superfine powder of each component, ebony 30g, astragalus 30g, chicory 25g, Liushenqu 25g, licorice 20g, mix for 5-15 minutes until uniform.

[0030] (4) Combine the mixture prepared in the above steps (2) and (3) into a mixer, add 450g of powdered sugar and 50g of flavoring ag...

example 1

[0032] Example 1: Pilot clinical trial for the treatment of chicken necrotic enteritis

[0033] 1 Materials and methods

[0034] 1.1 Test drugs

[0035] The traditional Chinese medicine superfine powder granule of the present invention, the recommended dosage is 1kg mixed with water 200kg, or 1kg of mixing material 100kg; contrast drug: 6.5% neomycin sulfate soluble powder.

[0036] 1.2 Test animals

[0037]450 1-day-old healthy white-feathered broiler chicks were purchased from a certain chicken farm in Shenyang, transported to our company's laboratory poultry house for cages, routine management, fed full-price feed until 10 days old, and no E. coli was detected by laboratory testing and other bacterial diseases can be regarded as experimental chickens. Wherein 100 are used for the pre-experiment of the challenge dose, and the remaining 350 test healthy chickens are divided into 7 groups, wherein 1, 2, and 3 groups are respectively the challenge group, and are the high, mi...

example 2

[0071] Example 2: Curative effect on clinically infected chicken necrotic enteritis and its influence on ileal flora

[0072] 1 Materials and methods

[0073] 1.1 Test drugs

[0074] Chinese medicine superfine powder granule of the present invention, recommended dosage 1kg is mixed with water 200kg, or 1kg mixing material 100kg; Contrast drug: the powder (100 order fine powders mixes) of Chinese medicine composition of the present invention, recommended dosage 1kg mixing material 100kg; 6.5% sulfuric acid Neomycin Soluble Powder.

[0075] 1.2 Test animals

[0076] In a broiler farm in Liaozhong County, Shenyang City, Liaoning Province, a 15-day-old commercial white-feather broiler chicken was naturally infected and diagnosed as chicken necrotic enteritis after autopsy and laboratory diagnosis.

[0077] 1.3 Test method

[0078] 330 diseased broilers with a body weight of 0.4-0.5kg were selected clinically from this chicken farm. The diseased chickens were isolated and raise...

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Abstract

The invention discloses traditional Chinese medicine ultra-micro powder granules for preventing and treating necrotic enteritis of poultry and a preparation method thereof, and aims to provide a traditional Chinese medicine composition for preventing and treating necrotic enteritis of chickens caused by clostridium welchii. The traditional Chinese medicine ultra-micro powder granules comprise the following components in mass fraction: common andrographis herb, berberis root, purslane, myrobalam, stemona root, dark plum, astragalus root, licorice, medicated leaven and chicory. The components are pure natural traditional Chinese medicinal materials, resources are wide and sufficient, the preparation is easy, and the cost is low. After the components are subjected to ultra-micro grinding and prepared into the granules, the palatability can be increased. After the granules are mixed or taken by drinking water, the medical effects of the traditional Chinese medicines are increased, and the intestinal flora is regulated, so that the granules have a better curative effect on necrotic enteritis of poultry. Compared with currently common medicines, the granules have the advantages of high safety, good curative effect, no residue and the like and guarantee the animal-derived food safety and human body health, so that the granules are good products for treating necrotic enteritis of poultry.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and relates to a traditional Chinese medicine superfine powder granule preparation, in particular to a traditional Chinese medicine superfine powder granule for preventing and treating poultry necrotic enteritis and a preparation method thereof. Background technique [0002] Clostridium perfringens, also known as Clostridium welchii, is a Gram-positive anaerobic bacillus that widely exists in the surrounding environment of poultry such as soil, water, and air. Clostridium perfringens is a common flora in the intestinal tract of chickens, which can be isolated from chickens of any age, even from chicken feathers and eggshells. Under normal circumstances, Clostridium perfringens will not cause disease when it lives in the intestinal tract, but when the intestinal environment changes or the intestinal tract is damaged, the normal intestinal flora is destroyed, and Clostridium perfringens will prol...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K9/16A61P1/00A61P31/04A61J3/00
Inventor 田凯王洪礼赵宝凯虞正伟
Owner SHENYANG VICA ANIMAL HUSBANDRY TECH
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