Traditional Chinese medicine composition for treating tuberculosis and preparation method thereof

A composition and tuberculosis technology, applied in the direction of drug combination, medical formula, drug delivery, etc., can solve the problems of large side effects, fast effect of western medicine, liver damage, etc., and achieve the effect of not easy to relapse, reliable curative effect, and low cost

Inactive Publication Date: 2016-07-06
青岛友诚高新技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the current treatment methods for tuberculosis are western medicines, which are quick in effect but have great side effects and cause varying degrees of damage to the stomach and liver

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] (1) A traditional Chinese medicine for the treatment of pulmonary tuberculosis, which is formed by the proportioning of the following raw materials by weight:

[0033] 30 parts of orchid, 25 parts of lotus, 20 parts of Anemarrhena, 15 parts of double kidney ginseng, 15 parts of round-leaf mallow, 10 parts of water umbrella, 10 parts of cinnamon, 10 parts of ginseng, 10 parts of wild watermelon seedlings, 5 parts of stone rice, 5 parts of astragalus.

[0034] (2) Preparation method:

[0035] In the first step, the lotus and Anemarrhena are mixed in proportion, extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then used Purify 1-2 times with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize int...

Embodiment 2

[0040] (1) a kind of Chinese medicine for the treatment of pulmonary tuberculosis is formed by the proportioning of following raw materials by weight: with embodiment 1.

[0041] (2) Preparation method:

[0042] In the first step, the lotus and Anemarrhena are mixed in proportion, extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then used Purify once with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize into powder;

[0043]In the second step, double kidney ginseng, mallow round leaf, shuiluo umbrella, and cinnamon are extracted twice with n-propanol with an alcohol concentration of 80%, and the extracts are combined, concentrated under reduced pressure, dried, and pulverized into powder, and the p...

Embodiment 3

[0047] 1. Long-term toxicity test process:

[0048] Apply Wistar rats (Beijing Weitong Lihua Experimental Animal Technology Co., Ltd. provides) experimental medicine is set to high, medium and low three dosages, be respectively the capsule 8g / kg, 4g / kg, 2g of embodiment 1 formula / kg. Calculated according to the human dose of 0.1g / kg / day tablet, it is 80 times, 40 times and 20 times of the effective dose for human respectively; another control group is set up, which is given continuously for 90 days and 180 days by intragastric administration and part of the animals are withdrawn for 10 days. Days later, the effects on various physiological and biochemical indicators of rats were observed. The experimental results show that: continuous oral administration of different doses to rats for 180 days has no effect on the food intake and weight growth of the rats. No significant toxic effects were found on liver and kidney function. There was no obvious effect on blood routine, bl...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating tuberculosis. The traditional Chinese medicine composition comprises goodyera schlechtendaliana, auriculateleaf aster, rhizoma anemarrhenae, toothed habenaria tuber, malva neglecta, fordia cauliflora, cinnamomum cassia, arenaria barbata, hibiscus trionum seed, all-grass of farges epigeneium and radix astragali. The invention also discloses a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the functions of nourishing yin and moistening lung, tonifying qi and consolidating exterior, invigorating spleen and removing dampness and promoting fluid production and resolving phlegm, realizes reliable curative effect at low cost, avoids toxic and side effects, rarely causes relapse and is suitable for tuberculosis.

Description

technical field [0001] The invention relates to a medical preparation, in particular to a traditional Chinese medicine composition for treating pulmonary tuberculosis and a preparation method thereof. Background technique [0002] Tuberculosis is an infectious disease of the lungs caused by Mycobacterium tuberculosis. The source of infection of Mycobacterium tuberculosis is mainly pulmonary tuberculosis patients who excrete bacteria, and it is transmitted through the respiratory tract. Healthy people infected with tuberculosis do not necessarily have the disease, only when the body's immunity is weakened. The patient had symptoms of tuberculosis poisoning, fever in the afternoon, accompanied by hot flushes on the cheeks, palms, and soles of the feet, night sweats, cough, expectoration, hemoptysis, chest pain, and dyspnea in severe cases. At present, most of the methods for treating tuberculosis are western medicines, which are quick in effect but have great side effects, w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/48A61K9/08A61P11/00A61P31/06
CPCA61K36/898A61K9/0019A61K9/08A61K9/4858A61K36/185A61K36/28A61K36/36A61K36/48A61K36/481A61K36/54A61K36/8964A61K47/02A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 不公告发明人
Owner 青岛友诚高新技术有限公司
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