Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Components and preparation method of leech biological activity small peptide medicine composition

A composition, leech technology, applied in the directions of drug combination, pharmaceutical formula, hydrolyzed protein ingredients, etc., can solve the problems of unsatisfactory use effect, skin redness, itching, and large human body damage, and achieves improvement of elasticity, elimination of facial fine lines, The effect of preventing the formation of melanin

Inactive Publication Date: 2016-05-04
ANHUI BIOLOGICAL PEPTIDE IND RES INST
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the improvement of modern living standards, people's pursuit of beauty is also constantly improving. People, especially women, hope to have a fair complexion and increase self-confidence, thus looking forward to effective whitening and anti-freckle products. And it usually contains chemical ingredients, not only the effect is not ideal, but also the damage to the skin is relatively large
There are some whitening products with remarkable effects on the market, but they are more harmful to the human body. Long-term use will cause redness, swelling, itching and other adverse reactions on the skin of the face, which brings troubles to users.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Components and preparation method of leech biological activity small peptide medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Prescription: leech small peptide 30g, total coumarin of Angelica dahurica 30g, total polysaccharides of aloe vera 20g, total flavonoids of ginkgo biloba 50g, silk fibroin small peptide 10g.

[0058] Preparation method: Preparation of small leech peptides: take leeches, crush them properly, add 5 times the amount of water to homogenate for 15 minutes, heat and boil for 30 minutes, let cool to room temperature, use hydrochloric acid to adjust the pH to 2.0±0.1, and then add 0.5% of the substrate Pepsin, enzymatically hydrolyze at 45°C for 1 hour, then use sodium hydroxide solution to adjust the pH to 7.0±0.1, add trypsin with 0.5% substrate amount, enzymolyze at 55°C for 1 hour, stir constantly and adjust the pH at 7.0±0.1, continue to heat up and boil for 15 minutes after enzymatic hydrolysis, let cool, centrifuge, collect the supernatant, adjust the pH to 7.0±0.1, add 1% activated carbon, stir evenly, filter, the filtrate has a molecular weight cut-off of 3kD The hollo...

Embodiment 2

[0065] Prescription: leech small peptide 60g, total coumarin of Angelica dahurica 60g, total polysaccharide of aloe vera 40g, total flavonoids of ginkgo 100g, silk fibroin small peptide 20g.

[0066] Preparation method: Preparation of small leech peptides: take leeches, crush them properly, add 5 times the amount of water to homogenate for 15 minutes, heat and boil for 30 minutes, let cool to room temperature, use hydrochloric acid to adjust the pH to 2.0±0.1, and then add 0.5% of the substrate Pepsin, enzymatically hydrolyze at 45°C for 1 hour, then use sodium hydroxide solution to adjust the pH to 7.0±0.1, add trypsin with 0.5% substrate amount, enzymolyze at 55°C for 1 hour, stir constantly and adjust the pH at 7.0±0.1, continue to heat up and boil for 15 minutes after enzymatic hydrolysis, let cool, centrifuge, collect the supernatant, adjust the pH to 7.0±0.1, add 1% activated carbon, stir evenly, filter, the filtrate has a molecular weight cut-off of 3kD The hollow fiber...

Embodiment 3

[0073] Prescription: leech small peptide 9kg, total coumarin of Angelica dahurica 10kg, total polysaccharide of aloe vera 5kg, total ginkgo flavonoids 15kg, silk fibroin small peptide 3kg.

[0074] Preparation method: Preparation of small leech peptides: take leeches, crush them properly, add 5 times the amount of water to homogenate for 15 minutes, heat and boil for 30 minutes, let cool to room temperature, use hydrochloric acid to adjust the pH to 2.0±0.1, and then add 0.5% of the substrate Pepsin, enzymatically hydrolyze at 45°C for 1 hour, then use sodium hydroxide solution to adjust the pH to 7.0±0.1, add trypsin with 0.5% substrate amount, enzymolyze at 55°C for 1 hour, stir constantly and adjust the pH at 7.0±0.1, continue to heat up and boil for 15 minutes after enzymatic hydrolysis, let cool, centrifuge, collect the supernatant, adjust the pH to 7.0±0.1, add 1% activated carbon, stir evenly, filter, the filtrate has a molecular weight cut-off of 3kD The hollow fiber m...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a leech small peptide effective part composition with freckle removing and whitening functions and belongs to the field of traditional Chinese medicine. The composition is prepared from leech small peptide extracted from leeches, angelica total coumarins extracted from radix angelicae dahuricae, aloe total polysaccharides extracted from aloe, ginkgo total flavonoids extracted from ginkgo leaves, and silk polypeptide extracted from silks according to a certain matching ratio, conventional auxiliary materials in pharmacy are added, the mixture is prepared into various preparation forms, and the prepared composition can be used for whitening the face and removing freckles.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine effective part composition with freckle-removing and whitening effects and a preparation method thereof, specifically Chinese medicine effective part composition extracted from leech, angelica dahurica, aloe, ginkgo biloba and silk, and a preparation method thereof, belonging to the field of traditional Chinese medicine . Background technique [0002] With the improvement of modern living standards, people's pursuit of beauty is also constantly improving. People, especially women, hope to have a fair complexion and increase self-confidence, thus looking forward to effective whitening and anti-freckle products. And usually contain chemical ingredients, not only the use effect is not ideal, but also relatively large damage to the skin. There are some whitening products with remarkable effect on the market, but they are more harmful to the human body. Long-term use will cause redness, swelli...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K38/01A61P17/00A61K36/896A61K36/886A61K35/62A61K35/64
CPCA61K9/1623A61K9/4858A61K35/62A61K36/16A61K36/232A61K36/886A61K36/896A61K38/012A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2236/55A61K2300/00
Inventor 凌中鑫刘国飞柏道鸣
Owner ANHUI BIOLOGICAL PEPTIDE IND RES INST
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com