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Traditional Chinese medicine composition for reducing blood viscosity and preparing method thereof

A technology of blood viscosity and composition, which is applied in the field of traditional Chinese medicine composition for reducing blood viscosity and its preparation, can solve problems such as poor effect and high price, and achieve increased blood fluidity, low cost, and relief of discomfort The effect of symptoms

Inactive Publication Date: 2016-03-23
青岛友诚高新技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many traditional Chinese medicine formulas for treating hyperlipidemia in the market, but most of them are ineffective and expensive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] (1) A traditional Chinese medicine for reducing blood viscosity, which is formed by proportioning the following raw materials by weight:

[0038] 30 parts of leech, 25 parts of tortoise shell, 20 parts of peach seven, 15 parts of lotus seed heart, 15 parts of honeysuckle, 10 parts of Bugwort, 10 parts of Milletah, 10 parts of manjusri, 10 parts of cassia seed, 5 parts of pig tooth soap, angelica 5 servings.

[0039] (2) Preparation method:

[0040] In the first step, tortoiseshell and Taoerqi are mixed in proportion, extracted 2-4 times with n-propanol whose alcohol concentration is 70-80% equivalent to 2-3 times the mass of the mixture, combined the filtrates, concentrated under reduced pressure, dried and Pulverize into powder, then purify with ethanol for 1-2 times, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize into powder;

[0041] In the second step, the lotu...

Embodiment 2

[0045] (1) A Chinese medicine for reducing blood viscosity, which is formed by the proportioning of the following crude drugs in parts by weight: the same as in Example 1.

[0046] (2) Preparation method:

[0047] In the first step, tortoiseshell and Taoerqi are mixed in proportion, extracted 2-4 times with n-propanol whose alcohol concentration is 70-80% equivalent to 2-3 times the mass of the mixture, combined the filtrates, concentrated under reduced pressure, dried and Pulverize into powder, then purify with ethanol for 1-2 times, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize into powder;

[0048] In the second step, the lotus seed heart, honeysuckle, spruce, and spaghetti are extracted 2-3 times with n-propanol with an alcohol concentration of 80-90%, and the extracts are combined, concentrated under reduced pressure, dried, and pulverized into powder. Add the pulver...

Embodiment 3

[0052] 1. Long-term toxicity test process:

[0053] Apply Wistar rats (Beijing Weitong Lihua Experimental Animal Technology Co., Ltd. provides) experimental medicine is set to high, medium and low three dosages, be respectively the capsule 8g / kg, 4g / kg, 2g of embodiment 1 formula / kg. Calculated according to the human dose of 0.1g / kg / day tablet, it is 80 times, 40 times and 20 times of the effective dose for human respectively; another control group is set up, which is given continuously for 90 days and 180 days by intragastric administration and part of the animals are withdrawn for 10 days. Days later, the effects on various physiological and biochemical indicators of rats were observed. The experimental results show that: continuous oral administration of different doses to rats for 180 days has no effect on the food intake and weight growth of the rats. No significant toxic effects were found on liver and kidney function. There was no obvious effect on blood routine, bl...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for effectively reducing blood viscosity. The traditional Chinese medicine composition is prepared from leeches, tortoise shells, sinopodophyllum hexandrum, lotus plumule, honeysuckle, stellaria uliginosa, caulis spatholobi, crinum asiaticum, semen cassiae, fructus gleditsiae and radix angelica sinensis. The invention further discloses a preparing method for the traditional Chinese medicine composition. The traditional Chinese medicine composition has the advantages of being good in curative effect, low in cost, high in cure rate and free of adverse reaction in the aspect of reducing blood viscosity. The traditional Chinese medicine composition can enhance the body physique of patients, improve blood mobility, reduce blood viscosity, and relieve various discomfort symptoms caused by blood viscosity; moreover, the preparing technology is simple, the toxic and side effect is small, the composition is easy to prepare, the raw materials are low in price, the preparing method is simple, and the traditional Chinese medicine composition has the good effects of reducing the blood viscosity and can be applied to clinical practice on a large scale.

Description

technical field [0001] The invention relates to a medical preparation, in particular to a traditional Chinese medicine composition for reducing blood viscosity and a preparation method thereof. Background technique [0002] Blood stickiness is also called blood thickening. It is called hyperviscosity in medicine, and middle-aged and elderly people are prone to suffer from it. It can be diagnosed by hemorheology examination. The main factors affecting blood viscosity are: blood cell factors, such as blood cell number, size, shape, red blood cell deformability, platelet function, etc. Plasma factors, such as plasma proteins (especially fibrinogen, immunoglobulin), blood sugar, blood lipids, fibrinolytic activity, etc. Vascular factors, such as vessel length, diameter, and intimal smoothness. [0003] Blood thickening is not an independent disease, but there are many clinical diseases, such as arteriosclerosis, cerebral thrombosis, myocardial infarction, hypertension, diabet...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P3/06A61K35/62A61K35/586
CPCA61K36/88A61K9/0019A61K9/08A61K9/1652A61K35/586A61K35/62A61K36/232A61K36/29A61K36/355A61K36/36A61K36/482A61K36/483A61K36/486A61K36/62A61K47/02A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 不公告发明人
Owner 青岛友诚高新技术有限公司
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