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Pharmaceutical composition for treating diabetes combined with renal fibrosis

A technology of renal fibrosis and composition, which is applied in the field of pharmaceutical composition for treating diabetes combined with renal fibrosis and its preparation, can solve problems such as unsatisfactory therapeutic effect and side effects of chemical drugs, and achieve good therapeutic effect and reasonable prescription

Inactive Publication Date: 2016-02-03
QINGDAO MERRITT MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the therapeutic effect of clinically used drugs for diabetes complicated with renal fibrosis is not satisfactory, and chemical drugs often cause serious side effects in the course of medication. Therefore, it is necessary to find a therapeutic drug that can effectively treat diabetes complicated with renal fibrosis and has less side effects. Become an urgent need in the industry

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 A pharmaceutical composition for treating diabetes complicated with renal fibrosis and its preparation method

[0021] A pharmaceutical composition for treating diabetes complicated with renal fibrosis, which is prepared from the following traditional Chinese medicine components in weight Kg: Codonopsis 45Kg, Cimicifuga 5.5Kg, oyster 30Kg, Pueraria 25Kg, Huai Dihuang 30Kg, Polygonatum 85Kg, Corydalis 15Kg , Curculigo 12Kg, Xu Changqing 5Kg, Herb 9Kg, Ginkgo biloba 10Kg, Guizhi 6Kg, Rhizoma Chuanxiong 10Kg.

[0022] A preparation method for treating diabetes mellitus with renal fibrosis, comprising the steps of:

[0023] (1) Soak oysters, rehmannia glutinosa, Curculigo curculigo, vanilla and ginkgo leaves in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then clathrate it with β-cyclodextrin, Prepare clathrate, clathrate and dregs for subsequent use;

[0024] ...

Embodiment 2

[0027] Embodiment 2 A kind of pharmaceutical composition and preparation method thereof for the treatment of diabetes complicated with renal fibrosis

[0028] A pharmaceutical composition for treating diabetes complicated with renal fibrosis, which is prepared from the following traditional Chinese medicine components in weight Kg: Codonopsis 60Kg, Cimicifuga 7Kg, oyster 40Kg, Pueraria 30Kg, Huai Dihuang 35Kg, Polygonatum 90Kg, Corydalis 20Kg, 15Kg curculigo, 10Kg Xu Changqing, 15Kg thin stem vanilla, 15Kg ginkgo biloba, 9Kg cassia twig, 15Kg Chuanxiong.

[0029] A preparation method for treating diabetes mellitus with renal fibrosis, comprising the steps of:

[0030] (1) Soak oysters, rehmannia glutinosa, Curculigo curculigo, vanilla and ginkgo leaves in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then clathrate it with β-cyclodextrin, Prepare clathrate, clathrate and dreg...

Embodiment 3

[0034] Example 3 A pharmaceutical composition for treating diabetes complicated with renal fibrosis and its preparation method

[0035] A pharmaceutical composition for treating diabetes mellitus complicated with renal fibrosis, which is prepared from the following traditional Chinese medicine components in weight Kg: Codonopsis 52.5Kg, Cimicifuga 6.5Kg, oyster 35Kg, Pueraria 27.5Kg, Huaidihuang 32.5Kg, Polygonatum 87.5Kg Kg, Corydalis 17.5Kg, Curculigo 13.5Kg, Xu Changqing 7.5Kg, Herb 12Kg, Ginkgo biloba 12.5Kg, Guizhi 7.5Kg, Rhizoma Chuanxiong 12.5Kg.

[0036] A preparation method for treating diabetes mellitus with renal fibrosis, comprising the steps of:

[0037] (1) Soak oysters, rehmannia glutinosa, Curculigo curculigo, vanilla and ginkgo leaves in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then clathrate it with β-cyclodextrin, Prepare clathrate, clathrate and dregs...

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Abstract

The invention belongs to the field of traditional Chinese medicines, relates to a pharmaceutical composition for treating diabetes combined with renal fibrosis and a preparation method for the pharmaceutical composition, and solves a problem that conventional medicines are poor in curative effect on diabetes combined with renal fibrosis. The traditional Chinese medicine composition for treating diabetes combined with renal fibrosis is prepared from the following traditional Chinese medicine components in parts by weight: 45-60 parts of radix codonopsitis, 5.5-7 parts of rhizoma cimicifugae, 30-40 parts of oyster, 25-30 parts of kudzuvine roots, 30-35 parts of rehmannia glutinosa libosch, 85-90 parts of rhizoma polygonati, 15-20 parts of corydalis tuber, 12-15 parts of curculigo orchioides, 5-10 parts of paniculate swallowwort roots, 9-15 parts of lysimachia capillipes hemsl, 10-15 parts of gingko leaves, 6-9 parts of cassia twig, and 10-15 parts of szechuan lovage rhizome. The pharmaceutical composition can improve clinical symptoms of a patient suffering from diabetes combined with renal fibrosis, and can remarkably reduce blood sugar and renal fibrosis indexes, so that the pharmaceutical composition is suitable for being popularized and applied in clinic.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating diabetes complicated with renal fibrosis and a preparation method thereof. Background technique [0002] Diabetes mellitus (DM) has an extremely high incidence rate and has become a worldwide disease. In addition to the disorder of glucose and lipid metabolism caused by the disease itself, various chronic complications in the eyes, kidneys, cardiovascular system, and nervous system have brought great pain to patients and even threatened their lives. Numerous studies in recent years have found that nitric oxide (NO) is closely related to the occurrence and development of DM and its complications. During the pathogenesis of DM, the body has obvious abnormal NO metabolism and enhanced lipid peroxidation, indicating that DM Various organ damages during the occurrence and development are related to abnormal NO metabolism and lipid pe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P3/10A61P13/12A61K35/618
Inventor 吴兴连
Owner QINGDAO MERRITT MEDICAL TECH CO LTD
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