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Preparation method and application for Mn-doped ZnS quantum-dot surface imprinting fluorescent probe

A fluorescent probe, surface imprinting technology, applied in fluorescence/phosphorescence, chemical instruments and methods, luminescent materials, etc., can solve the problems of poor selectivity, low sensitivity, complicated acrylamide operation, etc., and achieve fast fluorescence decay and luminous efficiency. High, improve the recognition efficiency and the effect of combining speed

Active Publication Date: 2016-01-13
JIANGSU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome defects such as complex detection of acrylamide in the prior art, low sensitivity, and poor selectivity, and provide a preparation method and application of a molecularly imprinted fluorescent probe on the surface of Mn-doped ZnS quantum dot graphene oxide

Method used

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  • Preparation method and application for Mn-doped ZnS quantum-dot surface imprinting fluorescent probe
  • Preparation method and application for Mn-doped ZnS quantum-dot surface imprinting fluorescent probe
  • Preparation method and application for Mn-doped ZnS quantum-dot surface imprinting fluorescent probe

Examples

Experimental program
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Effect test

Embodiment 1

[0033] (1) In a 250mL three-necked flask, add 3.594g of ZnSO4 ·7H 2 O, 0.198gMnC1 2 4H 2 O, add 80mL deionized water to dissolve, mix and stir for 20min at room temperature under nitrogen atmosphere, then add 10mL containing 3gNa dropwise 2 S·9H 2 O aqueous solution, the mixed solution was continuously stirred for 18h, and after centrifugation, the precipitate was obtained as Mn:ZnS quantum dots, and then the product was washed and dried with ethanol, and the 1gMn:ZnS quantum dots prepared above were dispersed in 40mL ethanol solution, gradually stirring under constant stirring. Add 1mL dropwise gamma -Mercaptopropyltriethoxysilane (KH-580), reflux at 80°C for 6 hours to obtain KH-580 modified Mn:ZnS quantum dots, wash the product with ethanol and dry it for later use.

[0034] (2) In a 100mL three-neck flask, add 50mgGO, then add 25mL ethanol for dissolution, stir well, add 0.5mL KH-580, stir at 50°C, then wash the product with ethanol, and dry it in a vacuum oven. Dispe...

Embodiment 2

[0042] (1) In a 250mL three-necked flask, add 3.594g of zinc sulfate (ZnSO 4 ·7H 2 O), 0.297g manganese chloride (MnCl 2 4H 2 (0), add 80mL deionized water to dissolve, mix and stir for 25min under room temperature nitrogen atmosphere, then add dropwise 10mL containing 3.0g sodium sulfide (Na 2 S·9H 2 (2) aqueous solution, the mixed solution is continuously stirred for 20h, and after centrifugation, the precipitation is obtained as Mn:ZnS quantum dots, then the product is washed and dried with ethanol, and then 1g of the above-mentioned Mn:ZnS quantum dots is dispersed in 42mL ethanol solution, and continuously Add 2 mL dropwise with stirring gamma -Mercaptopropyltriethoxysilane (KH-580), reflux reaction at 85°C to obtain KH-580 modified Mn:ZnS quantum dots, wash the product with ethanol and dry it for later use.

[0043] (2) In a 100mL three-neck flask, add 50mgGO, then add 25mL ethanol for dissolution, stir well, add 0.75mL KH-580, stir at 50°C, then wash the product wi...

Embodiment 3

[0048] (1) In a 250mL three-necked flask, add 3.594g of zinc sulfate (ZnSO 4 ·7H 2 O), 1.596g manganese chloride (MnCl 2 4H 2 (0), add 80mL deionized water to dissolve, mix and stir for 30min under room temperature nitrogen atmosphere, then add dropwise 10mL containing 3.0g sodium sulfide (Na 2 S·9H 2 (2) aqueous solution, the mixed solution is continuously stirred for 24h, and the precipitation is obtained after centrifugation as Mn:ZnS quantum dots, then the product is washed and dried with ethanol, and then 1g of the above-mentioned Mn:ZnS quantum dots obtained is dispersed in 45mL ethanol solution, continuously Add 3mL dropwise with stirring gamma -Mercaptopropyltriethoxysilane (KH-580), reflux reaction at 82°C to obtain KH-580 modified Mn:ZnS quantum dots, wash the product with ethanol and dry it for later use.

[0049] (2) In a 100mL three-neck flask, add 50mgGO, then add 25mL ethanol for dissolution, stir well, add 1mL KH-580, stir at 50°C, then wash the product wi...

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Abstract

The invention relates to a preparation method and application for a Mn-doped ZnS quantum-dot surface imprinting fluorescent probe, and belongs to the technical field of preparation of environment functional materials. By utilizing a free radical polymerization method and taking propionamide as a molecular imprinting polymer dummy template, methacrylic acid (MAA) as a functional monomer, Mn-doped ZnS quantum dot graphene oxide (Mn:ZnS@GO) as a matrix material, ethylene dimethacrylate (EGDMA) as a cross-linking agent, azodiisobutyronitrile (AIBN) as an initiator and N,N-dimethyl formamide (DMF) as a solvent, the surface imprinting fluorescent probe is synthesized and is used for enriching detection on acrylamide in food. The fluorescent probe prepared by employing the method embodiments advantages of surface molecular imprinting, avoids the molecule embedding excessive-deep problem of a molecular imprinting polymer template prepared by employing a conventional method, improves identification efficiency and combination speed, and also gives consideration to advantages of high luminescence efficiency, fast fluorescence attenuation and the like of the doped quantum dot, and improves detection rate and sensitivity.

Description

technical field [0001] The invention relates to a preparation method and application of a Mn-doped ZnS quantum dot surface imprinted fluorescent probe, in particular to a preparation method of a fluorescent acrylamide virtual molecular imprinted polymer based on Mn-doped ZnS quantum dots on the surface of graphene oxide and applications, belonging to the technical field of preparation of environmental functional materials. Background technique [0002] Acrylamide is a water-soluble neurotoxic substance that is carcinogenic to rodents. At present, some high-carbohydrate foods have been found to produce different levels of acrylamide after high-temperature cooking such as frying, roasting, and frying. And its content increases with the increase of processing temperature, which is a potential hazard to human health. In addition, polyacrylamide prepared by polymerization of acrylamide can be added to water as a flocculant to absorb and remove impurities in water, but a very sma...

Claims

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Application Information

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IPC IPC(8): C08F220/56C08F220/06C08F222/14C08F2/44C08K9/06C08K3/08C08K3/30B01J20/26B01J20/30C09K11/54C09K11/57C09K11/02G01N21/64
Inventor 刘燕仇健倪良孟祥国
Owner JIANGSU UNIV
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