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A traditional Chinese medicine composition with hypolipidemic effect and its preparation method and application

A technology for lowering blood lipid and composition, which is applied in the field of traditional Chinese medicine composition with blood lipid lowering effect and its preparation field, and can solve the problems of many medicinal flavors, insufficiently rigorous and scientific drug use, large dosage and the like.

Active Publication Date: 2018-10-19
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the current traditional Chinese medicine compound prescriptions have many medicinal flavors and large dosages, and the medication is not rigorous and scientific enough.

Method used

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  • A traditional Chinese medicine composition with hypolipidemic effect and its preparation method and application
  • A traditional Chinese medicine composition with hypolipidemic effect and its preparation method and application
  • A traditional Chinese medicine composition with hypolipidemic effect and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] 1. A Chinese medicine composition with hypolipidemic effect, which is made of rhubarb 24g, astragalus 20g and licorice 12g.

[0091] 2. the preparation method of the medicine with hypolipidemic effect of the present invention, it comprises the following steps:

[0092] (1) Get 24g of rhubarb, 20g of astragalus and 12g of licorice, add 16 times the weight of the medicinal materials, decoct and extract 3 times, each time for 2 hours, combine the extracts, and concentrate to obtain the extract;

[0093] (2) Mix the extract obtained in step (1) with carrier lactose or cornstarch evenly, granulate, and then pack into capsules to make capsules. (Lot number: 001)

Embodiment 2

[0095] 1. A Chinese medicine composition with hypolipidemic effect, which is made of rhubarb 12g, astragalus 40g and licorice 18g.

[0096] 2. the preparation method of the medicine with hypolipidemic effect of the present invention, it comprises the following steps:

[0097] (1) Get 12g of rhubarb, 40g of astragalus and 18g of licorice, add 12 times of the weight of the medicinal material to reflux extraction for 3 times, each time for 2 hours, combine the extracts, and concentrate to obtain an extract;

[0098] (2) Take the extract obtained in step (1), add distilled water to dissolve, filter, adjust the pH value, and make an oral liquid. (Lot No.: 002)

Embodiment 3

[0100] 1. a Chinese medicine composition with hypolipidemic effect, it is made of rhubarb 18g, astragalus 6g and licorice 6g.

[0101] 2. the preparation method of the medicine with hypolipidemic effect of the present invention, it comprises the following steps:

[0102] (1) Get 18g of rhubarb, 60g of Radix Astragali and 6g of Radix Glycyrrhizae, add 10 times of the weight of the medicinal materials to extract under reflux for 3 times, each time for 2 hours, combine the extracts, and concentrate to obtain the extract;

[0103] (2) Take the extract obtained in step (1), add diluent cyclodextrin or cornstarch, mix evenly, granulate, and dry to make granules. (Lot No.: 003)

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PUM

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Abstract

The present invention discloses a traditional Chinese medicinal composition with the effect of lowering blood fat, and a preparation method and application thereof. The composition consists of rheum officinale, Astragalus mongholicus and licorice in the weight ratio of 6:5:3. Based on the theory of syndrome differentiation in traditional Chinese medicine, the present invention conducts a large number of experiments to screen the traditional Chinese medicinal composition with the efficacy of significantly lowering cholesterol (CHO), triglyceride (TG) and high density protein cholesterol (HDL-C); a large number of experiments are conducted to screen the optimal ratio of the three medicinal materials. The traditional Chinese medicinal composition has the advantages of rigorous, scientific and rational administration, clear active ingredients, little side effects and safe and reliable administration, and can be used for prevention and treatment of atherosclerosis and thrombotic diseases.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a traditional Chinese medicine composition with blood lipid-lowering effect and its preparation method and application. Background technique [0002] The substantial improvement in living standards has led to major changes in people's eating habits. Similarly, in terms of blood lipids, it is manifested as: cholesterol (CHO), triglyceride (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and other indicators are generally increased. Among them, the harm of hypercholesterolemia is mainly Atheromatous plaques in large blood vessels can further cause vascular stenosis, coronary artery obstruction, acute myocardial infarction, cerebral infarction, renal arteriosclerosis and other diseases. Triglyceride (TG) is also a risk factor for inducing atherosclerosis and coronary heart disease. It can induce severe acute pancreatitis, high blood pressure, gallstones,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/708A61P3/06A61P9/10A61P7/02A61P1/16
Inventor 吴丽陈志鹏张峰李伟东
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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