A traditional Chinese medicine compound composition with the effect of treating hypertension and diabetes mellitus and its preparation method and application

Abstract

The invention discloses a traditional Chinese medicine compound composition capable of treating hypertensive patients with diabetes as well as a preparation method and application thereof. The traditional Chinese medicine compound composition is prepared from 15-45 parts of codonopsis pilosula, 15-45 parts of rehmannia root, 10-30 parts of danshen root, 10-30 parts of sophora flower bud, 10-30 parts of common lophatherum herb, 10-30 parts of reed rhizome, 10-30 parts of kudzuvine root, and 10-30 parts of perilla seed. The traditional Chinese medicine compound composition provided by the invention adopts a theory of treatment according to syndrome differentiation to have a prescription, and clinical experimental results show that the traditional Chinese medicine compound composition provided by the invention has comprehensive effects of multiple links and multiple targets, can improve clinical symptoms of hypertensive patients with diabetes, has the effects of lowering blood pressure and blood sugar and improving insulin resistance, and can be used for preventing and treating the hypertensive patients with diabetes; and the clinical experimental results show that the traditional Chinese medicine compound provided by the invention has no adverse reaction after long-term use and is safer to use.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a compound traditional Chinese medicine composition capable of treating hypertension combined with diabetes, a preparation method and application thereof. Background technique [0002] The incidence of essential hypertension (Essentia hypertension, EH) combined with type 2 diabetes mellitus (Type 2 Diabetes Mellitus, T2DM) is increasing year by year, and the incidence of hypertension combined with diabetes accounts for as high as 20% to 40% of the hypertensive population. The co-morbidity of EH and T2DM greatly increases the incidence of cardiovascular and cerebrovascular events and kidney damage, seriously infringing on the physical and mental health of patients. [0003] At present, there are many drugs for the treatment of hypertension combined with diabetes. Although the western medicines used clinically have certain curative effects, most of them have relatively lar...

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Problems solved by technology

[0003] At present, there are many drugs for the treatment of hypertension combined with diabetes. Although the western medicines used clinically have certain curative effects, most of them have relatively large adverse reactions, such as rebound after drug withdrawal, liver and kidney damage, rhabdomyolysis and other side effects. TCM has unique advantages in the treatment of hypertension combined with diabetes. There are many prescriptions and medicines for the prevention and treatment of hypertension combined with diabetes, and the curative effect is relatively long-lasting, and most of them have no obvious side effects. Prefer unilateral and proven prescriptions, lack of systematic and comprehensive clinical efficacy research, and the basis of traditional Chinese medicine prescriptions is different, and the treatment principles are not uniform

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