Supermicro powder for treating lamb diarrhoea and preparation method thereof

A technology of ultra-micro and powder, applied in the field of pharmaceutical preparations, can solve the problems of poor efficacy of lamb diarrhea, and achieve the effects of no acute toxicity and side effects, short course of treatment, and low cost

Inactive Publication Date: 2015-10-28
ANHUI AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the deficiencies in the prior art, provide a kind of superfine powder for the treatment of lamb diarrhea and preparation method thereof, to provide a kind of formula from a brand-new angle, solve the bacterial infection caused by various antibacterial drugs Antimicrobial resistance, and technical issues such as the increasingly ineffective use of antimicrobial western medicines in the treatment of lamb diarrhea

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1. Formula ingredients

[0020] By weight, take 3 parts of Schizonepeta charcoal, 1 part of Bupleurum bupleuri, 1 part of Comfrey, 2 parts of Jiaozhizi, 2 parts of Aurantium citrus charcoal and 1 part of potassium permanganate.

[0021] 2. Preparation method

[0022] (1) Preliminary pulverization: take by weighing the various Chinese herbal medicines except potassium permanganate according to the formula, mix, and make coarse powder with an ordinary pulverizer;

[0023] (2) Superfine pulverization: the coarse powder made in step (1) is added in proportion to potassium permanganate, and a cell-grade pulverizer is used for superfine pulverization to obtain ultrafine powders with a fineness of 300 mesh and above, namely The ultrafine powder.

[0024] 3. Clinical verification

[0025] Select 28 diseased lambs aged 5 to 15 days with the clinical manifestations of diarrhea, paralysis, and loss of appetite. Use 4 g of the ultrafine powder prepared by the above-mentioned met...

Embodiment 2

[0027] 1. Formula ingredients

[0028] By weight, 5 parts of Nepeta charcoal, 4 parts of Bupleurum bupleuri, 4 parts of Zicao, 4 parts of Jiaozhizi, 3 parts of Zhishi charcoal and 2 parts of potassium permanganate were taken.

[0029] 2. Preparation method

[0030] (1) Preliminary pulverization: take by weighing the various Chinese herbal medicines except potassium permanganate according to the formula, mix, and make coarse powder with an ordinary pulverizer;

[0031] (2) Superfine pulverization: the coarse powder made in step (1) is added in proportion to potassium permanganate, and a cell-grade pulverizer is used for superfine pulverization to obtain ultrafine powders with a fineness of 300 mesh and above, namely The ultrafine powder.

[0032] 3. Clinical verification

[0033] Select 39 diseased lambs aged 5 to 15 days with the clinical manifestations of diarrhea, paralysis, and loss of appetite. Use 4 g of the ultrafine powder prepared by the above-mentioned method per l...

Embodiment 3

[0035] 1. Formula ingredients

[0036] By weight, 7 parts of Schizonepeta Charcoal, 6 parts of Bupleurum, 6 parts of Comfrey, 7 parts of Jiaozhizi, 6 parts of Citrus Citrus Charcoal and 6 parts of Potassium Permanganate were taken.

[0037] 2. Preparation method

[0038] (1) Preliminary pulverization: take by weighing the various Chinese herbal medicines except potassium permanganate according to the formula, mix, and make coarse powder with an ordinary pulverizer;

[0039] (2) Superfine pulverization: the coarse powder made in step (1) is added in proportion to potassium permanganate, and a cell-grade pulverizer is used for superfine pulverization to obtain ultrafine powders with a fineness of 300 mesh and above, namely The ultrafine powder.

[0040] 3. Clinical verification

[0041] Select 31 diseased lambs aged 5 to 15 days with the clinical manifestations of diarrhea, paralysis, and loss of appetite. Use 4 g of the ultrafine powder prepared by the above-mentioned method...

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Abstract

The invention discloses a supermicro powder for treating lamb diarrhoea; the supermicro powder comprises the components by weight: 3-7 parts of schizonepetae herba carbonisata, 1-6 parts of radix bupleuri, 1-6 parts of lithospermum erythrorhizon, 2-7 parts of fructus gardeniae praeparatus, 2-6 parts of fructus aurantii immaturus carbonisata, and 1-6 parts of potassium permanganate. The supermicro powder has antibacterial, antiviral, anti-inflammatory, antidiarrheic and antipyretic effects, has the cure rate on lamb diarrhoea of more than or equal to 90%, and is remarkable in curative effect and short in drug use curative course; the supermicro powder formula components take the traditional Chinese medicines as the main components, so that the supermicro powder is high in safety, does not easily produce drug resistance on pathogenic bacteria, can be directly made into an oral preparation, is administrated by way of gavage, is direct to act and convenient to use, and has no acute toxicity and side effects; and in addition, the preparation method of the supermicro powder is simple, low in cost, and suitable for industrialized mass production.

Description

technical field [0001] The invention relates to a pharmaceutical preparation, in particular to an ultrafine powder for treating lamb diarrhea and a preparation method thereof. Background technique [0002] Lamb diarrhea is the main disease that causes a large number of lambs to die and hinders the growth and development of lambs. The disease has acute onset, strong infectivity, and high mortality; it is characterized by severe diarrhea, and in recent years there has been a syndrome of general paralysis; the etiology of the disease is complex, and the incidence and prevalence have no obvious seasonality and regularity. The common causes of the disease are as follows: lambs are malnourished due to improper feeding and management, and the body's disease resistance is poor; pathogenic factors such as bacteria, viruses, and parasites take the opportunity to invade the intestinal tract, directly stimulate the gastrointestinal mucosa, and disrupt the normal secretion of the gastroi...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/14A61P1/12A61K33/32
Inventor 韩春杨刘翠艳于海康佑汐陈华闫先超陈四玉刘亚云刘洪瑜高辉
Owner ANHUI AGRICULTURAL UNIVERSITY
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