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System and method for preparing microcapsules

A preparation system and microcapsule technology, applied in the field of materials, can solve the problems of the influence of material activity, the difficulty of encapsulating solid materials by emulsification method, and the complicated operation of self-assembly technology.

Inactive Publication Date: 2015-09-30
ANHUI UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides a system and method for preparing microcapsules, which can solve the complex problem of self-assembly technology operation, can solve the problem that the emulsification method is difficult to encapsulate solid materials, and can also solve the side-by-side high-voltage electrospray method. problems affecting the activity of the material,

Method used

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  • System and method for preparing microcapsules

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Experimental program
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Effect test

Embodiment 1

[0029] The preparation of embodiment 1 single-component microcapsules

[0030] First prepare the single-component microfluidic chip 7, then insert the micro-spray head 9 into the micro-fluidic chip 7 for output, and fix the micro-spray head through the set screw 8 of the spray head, and seal the port with UV glue; The four corners of the microfluidic chip 7 are fixed on the plane of the chip mounting bracket 5 with four screws 6, and the tail of the mounting bracket 5 is connected with the piezoelectric ceramic 3 by connecting bolts, and the piezoelectric ceramic 3 is fixed on the fixing seat 2, and the piezoelectric ceramic Ceramic 3 is connected with driving power 1 . The single-component solution is pumped into the microfluidic chip 7 from the inlet B of the first core material solution on the chip through the micropump, and the sodium alginate solution of the wall material is pumped into the microfluidic chip 7 from the inlet A of the wall material solution through the mic...

Embodiment 2

[0031] The preparation of embodiment 2 two-component microcapsules

[0032] First prepare the two-component microfluidic chip 7, then insert the micro-spray head 9 into the micro-fluidic chip 7 for output, and fix the micro-spray head through the set screw 8 of the print head, and seal the port with UV glue; The four corners of the microfluidic chip 7 are fixed on the plane of the chip mounting bracket 5 with four screws 6, and the tail of the mounting bracket 5 is connected with the piezoelectric ceramic 3 by connecting bolts, and the piezoelectric ceramic 3 is fixed on the fixing seat 2, and the piezoelectric ceramic Ceramic 3 is connected with driving power 1 . The two-component solution is pumped into the microfluidic chip 7 from the first core material solution inlet B and the second core material solution inlet C on the chip through the micropump, and the wall material sodium alginate solution is pumped from the wall material solution inlet A through the micropump. Inse...

Embodiment 3 3

[0033] The preparation of embodiment 3 three-component microcapsules

[0034]First prepare the two-component microfluidic chip 7, then insert the micro-spray head 9 into the micro-fluidic chip 7 for output, and fix the micro-spray head through the set screw 8 of the print head, and seal the port with UV glue; The four corners of the microfluidic chip 7 are fixed on the plane of the chip mounting bracket 5 with four screws 6, and the tail of the mounting bracket 5 is connected with the piezoelectric ceramic 3 by connecting bolts, and the piezoelectric ceramic 3 is fixed on the fixing seat 2, and the piezoelectric ceramic Ceramic 3 is connected with driving power 1 . The three-component solutions are pumped into the microfluidic chip 7 from the first core material solution inlet B, the second core material solution inlet C, and the third core material solution inlet D on the chip through the micropump, and the wall material sodium alginate solution is passed through the microflu...

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Abstract

The present invention provides a system and a method for preparing microcapsules, and relates to the technical field of materials. The system comprises a drive power supply, a piezoelectric ceramic, a bracket, a microfluidic chip, a micro pump, a micro spraying nozzle and a wall material reaction vessel. The method further comprises: injecting at least a solution to be prepared to the preparing system; emulsifying the injected solution to be prepared, such that the solution is in the micro-droplet form; and jetting the obtained solution having the micro-droplet form into the wall material solution so as to form the microcapsules through the reaction. According to the present invention, the microfluidic chip technology and the micro-jetting technology are firstly combined to carry out the metronomic microcapsule preparation, such that the mixing uniformity of the single component or multi-component solution and the capsule wall solution is enhanced, and the assurance is provided for the metronomic jetting of the microcapsules; and the microcapsule component configuration is flexible, wherein only the number of the inlet channels on the microfluidic chip and the channel geometry are changed so as to flexibly configure the number of the microcapsule components.

Description

technical field [0001] The invention relates to the field of material technology, in particular to a system and method for preparing microcapsules. Background technique [0002] Capsule or microcapsule reactor has broad application prospects in organic chemistry, analytical chemistry, molecular biology, medicinal chemistry, polymer chemistry, and nanomaterial preparation due to its unique structure and the special microenvironment it can provide. Its core idea is to construct a cell structure similar to living organisms consisting of molecularly recognized capsules and intracapsular cavities containing reaction media. In microcapsules, microparticles can be actively cultivated and proliferated, reducing the amount of exogenous environment. Effects on microparticles, such as cell particles. With the development of biological microcapsules, biologically active substances such as cells, enzymes, proteins and nucleic acids can be encapsulated in selectively permeable membranes....

Claims

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Application Information

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IPC IPC(8): B01J13/02
Inventor 穆莉莉荣莉郭书恒
Owner ANHUI UNIV OF SCI & TECH
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